Bibliografía

Ajedrea

  • Águila N, Cases M. Compuestos volátiles identificados en plantas in vitro de Satureja fruticosa L. (Ajedrea blanca). Madrid: Instituto de Investigaciones Agrarias (INIA); 1997.
  • Díaz R, Quevedo S, Ramos Cormenzana A. Phytochemical and antibacterial screening of some species of Spanish Lamiceae. Fitoterapia. 1988;59:4.
  • Fierascu I, Dinu-Pirvu CE, Fierascu RC, Velescu BS, Anuta V, Ortan A, et al. phytochemical profile and biological activities of Satureja hortensis L.: A review of the last decade. Molecules. 2018;23(10). pii: E2458.
  • Hajhashami V, Sadraei H, Ghannadi A, Mohseni M. Antiespasmodic and antidiarrhoeal effect of Satureja hortensis essential oil. J Ethnopharmacol. 2000;71:187-92.
  • Panizzi L, Flamini G, Cioni P, Morelli I. Composition and antimicrobial properties of essential oils of four Mediterranean Lamiaceae. J Ethnopharmacol. 1993;39:167-70.
  • Souza Brito ARM, Soua Brito AA. Medicinal plant research in Brazil: data from regional and national meetings. En: Balick MJ, Elisabetsky E, Laird SA, editores. Medicinal Resources of the Tropical Forest. New York: Columbia University Press; 1996.
  • Stanic G, Samarzija I. Diuretic effect on rats from Satureja montana L. Phytother Res. 1993;7:363.
  • Tepe B, Cilkiz M. A pharmacological and phytochemical overview on Satureja. Pharm Biol. 2016;54:375-412.

Ajo

  • Ahmad MS, Pischetsrieder M, Ahmed N. Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation products. Eur J Pharmacol 2007; 561: 32-38.
  • Ahmadian F, Mozaffari-Khosravi H, Azaraein MH, Faraji R, Zavar-Reza J. The effect of consumption of garlic tablet on proteins oxidation biomarkers in postmenopausal osteoporotic women: A randomized clinical trial. Electron Physician. 2017; 9 (11): 5670-5675. doi: 10.19082/5670.
  • Allison GL, Lowe GM, Rahman K. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms. J Nutr 2006; 136: 782S-788S.
  • Atkin M, Laight D, Cummings MH. The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial. J Diabetes Complications. 2016; 30 (4): 723-7. doi: 10.1016/j.jdiacomp.2016.01.003.
  • Berginc K, Milisav I, Kristl A. Garlic flavonoids and organosulfur compounds: impact on the hepatic pharmacokinetics of saquinavir and darunavir. Drug Metab Pharmacokinet 2011; 25:521-30.
  • Budoff M. Aged garlic extract retards progression of coronary artery calcification. J Nutr 2006; 136: 741S-744S.
  • Chan KC, Yin MC, Chao WJ. Effect of diallyl trisulfide-rich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats. Food Chem Toxicol 2007; 45: 502-507.
  • Choi S, Oh DS, Jerng UM. A systematic review of the pharmacokinetic and pharmacodynamic interactions of herbal medicine with warfarin. PLoS One. 2017;12(8):e0182794.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Allium sativum L., bulbus. Draft. London: EMA. Doc. Ref.: EMA/HMPC/7685/2013. Adopted: 12 July 2016.
  • Felix TC, de Brito Röder DVD, Dos Santos Pedroso R. Alternative and complementary therapies for vulvovaginal candidiasis. Folia Microbiol (Praha). 2018 Sep 30.
  • Hannan A, Ikramullah M, Usman M, Hussain S, Absar M, Javed K. Anti-mycobacterial activity of garlic (Allium sativum) against multi-drug resistant and non-multi-drug resistant mycobacterium tuberculosis. Pak J Pharm Sci. 2011; 24: 81-85.
  • Howard EW, Ling MT, Chua CW, Cheung HW, Wang X, Wong YC. Garlic-derived S-allylmercaptocysteine is a novel in vivo antimetastatic agent for androgen-independent prostate cancer. Clin Cancer Res 2007; 13: 1847-1856.
  • Jung ES, Park SH, Choi EK, Ryu BH, Park BH, Kim DS, et al. Reduction of blood lipid parameters by a 12-wk supplementation of aged black garlic: a randomized controlled trial. Nutrition. 2014; 30 (9): 1034-9. doi: 10.1016/j.nut.2014.02.014.
  • Li Z, Ying X, Shan F, Ji J. The association of garlic with Helicobacter pylori infection and gastric cancer risk: A systematic review and meta-analysis. Helicobacter. 2018;23(5):e12532.
  • Matsumoto S, Nakanishi R, Li D, Alani A, Rezaeian P, Prabhu S, et al. Aged Garlic Extract Reduces Low Attenuation Plaque in Coronary Arteries of Patients with Metabolic Syndrome in a Prospective Randomized Double-Blind Study. J Nutr. 2016; 146 (2): 427S-432S. doi: 10.3945/jn.114.202424.
  • Navarro MC. Posibilidades terapéuticas del bulbo de ajo (Allium sativum). Revista de Fitoterapia 2007; 7: 131-151.
  • Pardo de Santayana M, Morales R. - Fitoterapia popular. Plantas medicinales de uso tradicional en la península ibérica. En: Fresquet JL, Aguirre CP (Eds.). 5th European Colloquium on Ethnopharmacology - The cultural interbreeding in ethnopharmacology: from indigenous to scientific knowledges. Revista de Fitoterapia 2005; 5 (Supl 1): 212-226.
  • Percival SS. Aged Garlic Extract Modifies Human Immunity. J Nutr. 2016;146 (2): 433S-436S. doi: 10.3945/jn.115.210427.
  • Rahman K, Lowe GM. Garlic and cardiovascular disease: A critical review. J Nutr 2006; 136: 736S-740S.
  • Ried K, Frank OR, Stocks NP. Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial. Eur J Clin Nutr. 2013; 67 (1): 64-70. doi: 10.1038/ejcn.2012.178.
  • Ried K, Travica N, Sali A. The effect of aged garlic extract on blood pressure and other cardiovascular risk factors in uncontrolled hypertensives: the AGE at Heart trial. Integr Blood Press Control. 2016; 9: 9-21. doi: 10.2147/IBPC.S93335.
  • Rohner A, Ried K, Sobenin IA, Bucher HC, Nordmann AJ. A systematic review and metaanalysis on the effects of garlic preparations on blood pressure in individuals with hypertension. Am J Hypertens. 2015; 28 (3): 414-23. doi: 10.1093/ajh/hpu165.
  • Ryu JH, Kang D. Physicochemical properties, biological activity, health benefits, and general limitations of aged black garlic: a review. Molecules. 2017;22(6). pii: E919.
  • Sobenin IA, Pryanishnikov VV, Kunnova LM, Rabinovich YA, Martirosyan DM, Orekhov AN. The effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery disease. Lipids Health Dis 2010; 9:119 -124.
  • Son EW, Mo SJ, Rhee DK, Pyo S. Inhibition of ICAM-1 expression by garlic component, allicin, in γ-irradiated human vascular endothelial cells via downregulation of the JNK signalling pathway. Int Immunopharmacol 2006; 6: 1788-1795.
  • Stevinson C, Pittler MH, Ernst E. Garlic for treating hypercholesterolemia. A meta-analysis of randomised clinical trials. Ann Intern Med 2000; 19: 420-429.
  • Sun YE, Wang W, Qin J. Anti-hyperlipidemia of garlic by reducing the level of total cholesterol and low-density lipoprotein: A meta-analysis. Medicine (Baltimore). 2018;97(18):e0255.
  • Varshney R, Budoff MJ. Garlic and Heart Disease. J Nutr. 2016; 146 (2): 416S-421S. doi: 10.3945/jn.114.202333.
  • Watson CJ, Grando D, Fairley CK, Chondros P, Garland SM, Myers SP, et al. The effects of oral garlic on vaginal candida colony counts: a randomised placebo controlled double-blind trial. BJOG. 2014; 121 (4): 498-506. doi: 10.1111/1471-0528.12518.
  • Williams MJA, Sutherland HF, McCormick MP, de Jong DJ, de Jong S. Aged garlic extract improves endothelial function in men with coronary artery disease. Phytother Res 2005; 19: 314-319.
  • Zeb I, Ahmadi N, Nasir K, Kadakia J, Larijani VN, Flores F, et al. Aged garlic extract and coenzyme Q10 have favorable effect on inflammatory markers and coronary atherosclerosis progression: A randomized clinical trial. J Cardiovasc Dis Res. 2012; 3 (3): 185-90. doi: 10.4103/0975-3583.98883.
  • Zeng T, Zhang CL, Zhao XL, Xie KQ. The roles of garlic on the lipid parameters: a systematic review of the literature. Crit Rev Food Sci Nutr. 2013; 53 (3): 215-30. doi: 10.1080/10408398.2010.523148.

Albahaca

  • Bower A, Marquez S, de Mejia EG. The health benefits of selected culinary herbs and spices found in the traditional Mediterranean diet. Crit Rev Food Sci Nutr. 2016;56(16):2728-46.
  • Mehriardestani M, Aliahmadi A, Toliat T, Rahimi R. Medicinal plants and their isolated compounds showing anti-Trichomonas vaginalis- activity. Biomed Pharmacother. 2017;88:885-893.
  • Sestili P, Ismail T, Calcabrini C, Guescini M, Catanzaro E, Turrini E, et al. The potential effects of Ocimum basilicum on health: a review of pharmacological and toxicological studies. Expert Opin Drug Metab Toxicol. 2018;14(7):679-692.

Alcachofera

  • Barrat E, Zaïr Y, Ogier N, Housez B, Vergara C, Maudet C, et al. A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial. Int J Food Sci Nutr. 2013; 64 (7): 882-9. doi: 10.3109/09637486.2013.809405.
  • Barrat E, Zaïr Y, Sirvent P, Chauveau P, Maudet C, Housez B, et al. Effect on LDL-cholesterol of a large dose of a dietary supplement with plant extracts in subjects with untreated moderate hypercholesterolaemia: a randomised, double-blind, placebo-controlled study. Eur J Nutr. 2013; 52 (8): 1843-52. doi: 10.1007/s00394-012-0486-2.
  • Brown JE, Rice-Evans CA. Luteolin-rich Artichoke extract protects low density lipoprotein from oxidation in vitro. Free Rad Res 1998, 29: 247-255.
  • Bundy R, Walker AF, Middleton RW, Wallis C, Simpson HC. Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trial. Phytomedicine 2008; 15: 668-75.
  • Emendörfer F, Emendörfer F, Bellato F, Noldin VF, Cechinel-Filho V, Yunes RA, Delle Monache F, Cardozo AM. Antispasmodic activity of fractions and cynaropicrin from Cynara scolymus on guinea-pig ileum. Biol Pharm Bull. 2005; 28: 902-4.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European herbal monograph on Cynara cardunculus (syn. Cynara scolymus L.), folium. London: EMA. Doc. Ref.: EMA/HMPC/194014/2017. Adopted: 27/3/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Assessment report on Cynara cardunculus (syn. Cynara scolymus L.), folium. London: EMA. Doc. Ref.: EMA/HMPC/194013/2017. Adopted: 27/3/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). List of references supporting the assessment report on Cynara cardunculus (syn. Cynara scolymus L.), folium. London: EMA. Doc. Ref.: EMA/HMPC/194012/2017. Adopted: 27/3/2018.
  • Fantini N, Colombo G, Giori A, Riva A, Morazzoni P, Bombardelli E, Carai MA. Evidence of glycemia-lowering effect by a Cynara scolymus L. extract in normal and obese rats. Phytother Res 2010; 25: 463-6.
  • Gebhardt R. Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L) against hydoperoxide-induced oxidative stress in cultured rat hepatocytes. Toxicol Applied Pharmacol 1997; 144: 279-286.
  • Gebhardt R. Inhibition of cholesterol biosynthesis in primary cultured rat hepatocytes by artichoke (Cynara scolymus L) extracts. J. Pharm. Exp. Ther. 1998, 286: 1122-1128.
  • Holtmann G, Adam B, Haag S, Collet W, Grünewald E, Windeck T. Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial. Aliment Pharmacol Ther 2003; 18: 1099-105.
  • Huber R, Müller M, Naumann J, Schenk T, Lüdtke R. Artichoke leave extract for chronic hepatitis C - a pilot study. Phytomedicine 2009; 16: 801-4.
  • Huber R, Müller M, Naumann J, Schenk T, Lüdtke R. Artichoke leave extract for chronic hepatitis C — a pilot study. Phytomedicine. 2009;16:801-4.
  • Küçükgergin C, Aydin AF, Ozdemirler-Erata G, Mehmetçik G, Koçak-Toker N, Uysal M. Effect of artichoke leaf extract on hepatic and cardiac oxidative stress in rats fed on high cholesterol diet. Biol Trace Elem Res. 2010;135:264-74.
  • Küskü-Kiraz Z, Mehmetçik G, Dogru-Abbasoglu S, Uysal M. Artichoke leaf extract reduces oxidative stress and lipoprotein dyshomeostasis in rats fed on high cholesterol diet. Phytother Res. 2010;24:565-70.
  • Mehmetçik G, Ozdemirler G, Koçak-Toker N, Cevikbaş U, Uysal M. Effect of pretreatment with artichoke extract on carbon tetrachloride-induced liver injury and oxidative stress. Exp Toxicol Pathol. 2008;60:475-80.
  • Panahi Y, Kianpour P, Mohtashami R, Atkin SL, Butler AE, Jafari R, et al. Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial. Phytother Res. 2018;32(7):1382-1387.
  • Pérez García F, Marín E, Adzet T, Cañigueral S. Activity of artichoke leaf extract on reactive oxygen species. Free Rad Res. 2000;33:661-5.
  • Pittler MH, Verster JC, Ernst E. Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials. BMJ. 2005;331:1515-8.
  • Rangboo V, Noroozi M, Zavoshy R, Rezadoost SA, Mohammadpoorasl A. The effect of artichoke leaf extract on alanine aminotransferase and aspartate aminotransferase in the patients with nonalcoholic steatohepatitis. Int J Hepatol. 2016;2016:4030476.
  • Rondanelli M, Giacosa A, Morazzoni P, Guido D, Grassi M, Morandi G, et al. MediterrAsian diet products that could raise hdl-cholesterol: a systematic review. Biomed Res Int. 2016;2016:2025687.
  • Rondanelli M, Giacosa A, Orsini F, Opizzi A, Villani S. Appetite control and glycaemia reduction in overweight subjects treated with a combination of two highly standardized extracts from Phaseolus vulgaris and Cynara scolymus. Phytother Res. 2011;25:1275-82.
  • Rondanelli M, Monteferrario F, Perna S, Faliva MA, Opizzi A. Health-promoting properties of artichoke in preventing cardiovascular disease by its lipidic and glycemic-reducing action. Monaldi Arch Chest Dis. 2013;80(1):17-26.
  • Rondanelli M, Opizzi A, Faliva M, Sala P, Perna S, Riva A, et al. Metabolic management in overweight subjects with naive impaired fasting glycaemia by means of a highly standardized extract from Cynara scolymus: a double-blind, placebo-controlled, randomized clinical trial. Phytother Res. 2014;28:33-41.
  • Salekzamani S, Ebrahimi-Mameghani M, Rezazadeh K. The antioxidant activity of artichoke (Cynara scolymus): A systematic review and meta-analysis of animal studies. Phytother Res. 2018 Oct 22.
  • Sannia A. Phytotherapy with a mixture of dry extracts with hepato-protective effects containing artichoke leaves in the management of functional dyspepsia symptoms. Minerva Gastroenterol Dietol. 2010;56:93-9.
  • Santos HO, Bueno AA, Mota JF. The effect of artichoke on lipid profile: A review of possible mechanisms of action. Pharmacol Res. 2018;137:170-178.
  • Speroni E, Cervellati R, Govoni P, Guizzardi S, Renzulli C, Guerra MC. Efficacy of different Cynara scolymus preparations on liver complaints. J Ethnopharmacol. 2003;86:203-11.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Walker A, Middleton R, Petrowicz O. Artichoke leaf extract reduces symptoms of irritable bowel syndrome in a post-marketing surveillance study. Phytother Res. 2001;15:58-61.
  • Wider B, Pittler MH, Thompson-Coon J, Ernst E. Artichoke leaf extract for treating hypercholesterolaemia. Cochrane Database Syst Rev. 2009;(4):CD003335.

Amapola

  • Gamboa PM, Jauregui I, Urrutia I, Gonzalez G, Barturen P, Antepara I. Allergic contact urticaria from poppy flowers (Papaver rhoeas). Contact Dermatitis. 1997; 37 (3): 140-1.
  • Schaffer S, Schmitt-Schillig S, Müller WE, Eckert GP. Antioxidant properties of Mediterranean food plant extracts: geographical differences. J Physiol Pharmacol. 2005; 56 (Suppl 1): 115-24.
  • Soulimani R, Younos C, Jarmouni-Idrissi S, Bousta D, Khalouki F, Laila A. Behavioral and pharmaco-toxicological study of Papaver rhoeas L. in mice. Journal of Ethnopharmacology 2001; 74: 265-274.

Anís Estrellado

  • Alós Almiñana M, Marco Peiró S, Beltrán Martinavarro B, Intoxicación por anís estrellado. Información Farmacoterapéutica de la Comunitat Valenciana 2010; vol. 2 (6): 3-4.
  • Bhadra S, Mukherjee PK, Kumar NS, Bandyopadhyay A, Anticholinesterase activity of standardized extract of Illicium verum Hook. F. Fruits. Fitoterapia 2011; 82: 342-346.
  • Madden GR, Schmitz KH, Fullerton K. A case of infantile star anise toxicity. Pediatr Emerg Care. 2012; 28 (3): 284-5. doi: 10.1097/PEC.0b013e3182495ba7.

Anís Verde

  • European Medicines Agency (EMA)-Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Pimpinella anisum L. aetheroleum. London: EMA. Doc. Ref: EMEA/HMPC/263273/2006. Adopted: 17/6/2014.
  • Ghoshegir SA, Mazaheri M, Ghannadi A, Feizi A, Babaeian M, Tanhaee M, et al. Pimpinella anisum in the treatment of functional dyspepsia: A double-blind, randomized clinical trial. J Res Med Sci. 2015; 20 (1): 13-21.
  • Ghoshegir SA, Mazaheri M, Ghannadi A, Feizi A, Babaeian M, Tanhaee M, et al. Pimpinella anisum in modifying the quality of life in patients with functional dyspepsia: A double-blind randomized clinical trial. J Res Med Sci. 2014; 19 (12): 1118-23.
  • Mosaffa-Jahromi M, Lankarani KB, Pasalar M, Afsharypuor S, Tamaddon AM. Efficacy and safety of enteric coated capsules of anise oil to treat irritable bowel syndrome. J Ethnopharmacol. 2016 Dec 24;194:937-946. doi: 10.1016/j.jep.2016.10.083.
  • Nahidi F, Kariman N, Simbar M, Mojab F. The Study on the Effects of Pimpinella anisum on Relief and Recurrence of Menopausal Hot Flashes. Iran J Pharm Res. 2012; 11 (4): 1079-85.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia 2014; 14 (1): 5–36.

Arenaria

  • Al-Qura'n S. Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan Ethnopahrmacology 2009; 123:45-50.
  • Wojnicz D, Kucharska AZ, Sokół-Łętowska A, Kicia M, Tichaczek-Goska D. Medicinal plants extracts affect virulence factors expression and biofilm formation by the uropathogenic Escherichia coli. Urol Res 2012; 40 (6): 683-97. doi: 10.1007/s00240-012-0499-6.

Arnica

  • Chaiet SR, Marcus BC. Perioperative Arnica montana for reduction of ecchymosis in rhinoplasty surgery. Ann Plast Surg. 2016 May;76(5):477-82. doi: 10.1097/SAP.0000000000000312.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Arnica montana L., flos. London: EMA. Doc. Ref. EMA/HMPC/198793/2012. Adopted: 6 May 2014.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Herbal medicine: summary for the public. Arnica flower (Arnica montana L., flos). London: EMA. Doc. Ref. EMA/654173/2016. Adopted: 22 November 2016.
  • Jäger C, Hrenn A, Zwingmann J, Suter A, Merfort I. Phytomedicines prepared form Arnica flowers inhibit the transcription factors AP-1 and NF-kappaB and modulate the activity of MMP1 and MMP13 in human and bovine chondrocytes. Planta Med 2009; 75 (12): 1319-1325.
  • Klaas CA, Wagner G, Laufer S, Sosa S, Della Loggia R,Bomme U, et al. Studies on the anti-inflammatory activity of phytopharmaceuticals prepared form arnica flowers. Planta Med 2002; 68 (5): 385-391.
  • Knuesel O, Weber M, Suter A. Arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial. Adv Ther 2002, 19 (5): 209-218. Leu S, Havey J, White LE, Martin N, Yoo SS, Rademaker AW, et al. Accelerated resolution of laser-induced bruising with topical 20% arnica: a rater-blinder randomized controlled trial. Br J Dermatol 2010; 163 (3): 557-563.
  • Lyss G, Knorre A, Schimidt TJ, Pahl HL, Merfort I. The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65. J Biol Chem 1998; 273 (50): 33508-33516.
  • Ross SM. Osteoarthritis: a proprietary Arnica gel is found to be as effective as ibuprofen gel in osteoarthritis of the hands. Holist Nurs Pract. 2008; 22 (4): 237-9. doi: 10.1097/01.HNP.0000326007.03429.3e.
  • Verma N, Tripathi SK, Sahu D, Das HR, Das RH. Evaluation of inhibitory activites of plant extracts on production of LPS-stimulated pro-inflammatory mediators in J774 murine macrophagues. Mol Cell Biochem 2010; 336 (1-2): 127-135.
  • Widrig R, Suter A, Saller R, Melzer J. Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomized, double-blind study. Rheumatol Int 2007; 27 (6): 585-591.
  • Widrig R, Suter A, Saller R, Melzer J. Estudio clínico comparativo: gel de árnica frente a gel de ibuprofeno en el tratamiento tópico de la osteoartritis de la mano. Revista de Fitoterapia 2007; 7 (2): 101-112.
  • Wijnsma R; Woerdenbag HJ; Busse W. Die Bedeutung von Arnika-Arten in der Phytotherapie. Z. Phytotherapie 1995; 16:48-62.

Azahar

  • Akhlaghi M, Shabanian G, Rafieian-Kopaei M, Parvin N, Saadat M, Akhlaghi M. Citrus aurantium blossom and preoperative anxiety. Rev Bras Anestesiol. 2011; 61 (6): 702-12. doi: 10.1016/S0034-7094(11)70079-4.
  • Astell KJ, Mathai ML, Su XQ. A review on botanical species and chemical compounds with appetite suppressing properties for body weight control. Plant Foods Hum Nutr. 2013; 68 (3): 213-21. doi: 10.1007/s11130-013-0361-1.
  • Bent S, Padula A, Neuhaus J. Safety and efficacy of Citrus aurantium for weight loss. Am J Cardiol 2004; 94 (10): 1359-61.
  • Carvalho-Freitas MI, Costa M. Anxiolytic and sedative effects of extracts and essential oil from Citrus aurantium L. Biol Pharm Bull 2002; 25 (12): 1629-33.
  • Dosoky NS, Setzer WN. Biological activities and safety of Citrus spp. essential oils. Int J Mol Sci. 2018;19(7). pii: E1966. doi: 10.3390/ijms19071966.
  • Farshbaf-Khalili A, Kamalifard M, Namadian M. Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women: A triple-blind, randomized, controlled clinical trial. Complement Ther Clin Pract. 2018;31:132-138. doi: 10.1016/j.ctcp.2018.02.004.
  • Haaz S, Fontaine KR, Cutter G, Limdi N, Perumean-Chaney S, et al. Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. Obes Rev 2006; 7 (1): 79-88.
  • Heydari N, Abootalebi M, Jamalimoghadam N, Kasraeian M, Emamghoreishi M, Akbarzadeh M. Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students: A clinical trial study. Complement Ther Clin Pract. 2018;32:1-5.
  • Matsuzaki K, Miyazaki K, Sakai S, Yawo H, Nakata N, Moriguchi S, et al. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. Eur J Pharmacol 2008; 578 (2-3): 194-200.
  • Haaz S, Fontaine KR, Cutter G, Limdi N, Perumean-Chaney S, Allison DB. Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. Obes Rev. 2006; 7 (1): 79-88.
  • Heydari N, Abootalebi M, Jamalimoghadam N, Kasraeian M, Emamghoreishi M, Akbarzadeh M. Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students: A clinical trial study. Complement Ther Clin Pract. 2018;32:1-5. doi: 10.1016/j.ctcp.2018.04.006.
  • Morand C, Dubray C, Milenkovic D, Lioger D, Martin JF, Scalbert A, et al. Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers. Am J Clin Nutr. 2011; 93 (1): 73-80.
  • Preuss HG, Di Ferdinando D, Bagchi M, Bagchi D. Citrus aurantium as a thermogenic, weight-reduction replacement for ephedra: an overview. J Med 2002; 33 (1-4): 247-64.
  • Ratamess NA, Bush JA, Kang J, Kraemer WJ, Stohs SJ, Nocera VG, et al. The Effects of supplementation with p-synephrine alone and in combination with caffeine on metabolic, lipolytic, and cardiovascular responses during resistance exercise. J Am Coll Nutr. 2016; 35 (8): 657-669.
  • Seifert JG, Nelson A, Devonish J, Burke ER, Stohs SJ. Effect of acute administration of an herbal preparation on blood pressure and heart rate in humans. Int J Med Sci. 2011; 8 (3): 192-7.
  • Shara M, Stohs SJ, Mukattash TL. Cardiovascular safety of oral p-synephrine (bitter orange) in healthy subjects: a randomized placebo-controlled cross-over clinical trial. Phytother Res. 2016; 30 (5): 842-7. doi: 10.1002/ptr.5590.
  • Spencer JP. The impact of fruit flavonoids on memory and cognition. Br J Nutr 2010; 104 Suppl 3: S40-7.
  • Stohs SJ. Safety, Efficacy, and Mechanistic Studies regarding Citrus aurantium (bitter orange) extract and p-synephrine. Phytother Res. 2017; 31 (10): 1463-1474. doi: 10.1002/ptr.5879.
  • Stohs SJ, Preuss HG, Keith SC, Keith PL, Miller H, Kaats GR. Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. Int J Med Sci. 2011; 8 (4): 295-301.
  • Stohs SJ, Preuss HG, Shara M. A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects. Oxid Med Cell Longev. 2011; 2011: 482973. doi: 10.1155/2011/482973.
  • Stohs SJ, Preuss HG, Shara M. The safety of Citrus aurantium (bitter orange) and its primary protoalkaloid p-synephrine. Phytother Res. 2011; 25 (10): 1421-8. doi: 10.1002/ptr.3490.
  • Suntar I, Khan H, Patel S, Celano R, Rastrelli L. An overview on Citrus aurantium L.: its functions as food ingredient and therapeutic agent. Oxid Med Cell Longev. 2018;2018:7864269. doi: 10.1155/2018/7864269.

Boldo

  • Backhouse N, Delporte C, Givernau M, Cassels BK, Valenzuela A, Speisky H. Anti-inflammatory and antipyretic effects of boldine. Agents Actions 1994, 42: 114-117.
  • Braga AC, Oliveira MB, Feliciano GD, Reiniger IG, Oliveira JF., Silva CR, et al. The effect of drugs on the labeling of blood elements with technetium-99m. Curr. Pharm Des 2000, 6: 1179-1191.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Peumus boldus Molina, folium. London: EMA. Doc. Ref.: EMA/HMPC/453725/2016. Adopted: 22 November 2016.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final assessment report on Peumus boldus Molina, folium. London: EMA. Doc. Ref.: EMA/HMPC/453726/2016. Adopted: 22 November 2016.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final list of references supporting the assessment of Peumus boldus Molina, folium. London: EMA. Doc. Ref.: EMA/HMPC/747075/2016. Adopted: 22 November 2016.
  • Kubinova R, Machala M, Minksova K, Neca J, Suchy V Chemoprotective activity of boldine: modulation of drug-metabolizing enzymes. Pharmazie 2001, 56: 242-243.
  • OBrien P, Carrasco-Pozo C, Speisky H. Boldine and its antioxidant or health-promoting properties. Chem Biol Interact 2006; 159 (1): 1-17.
  • Schmeda-Hirschmann G, Rodriguez JA, Theoduloz C, Astudillo SL, Feresin GE, Tapia A. Free-radical scavengers and antioxidants from Peumus boldus Mol. ("Boldo"). Free Radic Res 2003; 37 (4): 447-52.
  • Speisky H, Cassels BK. Boldo and boldine: an emerging case of natural drug development. Pharmacol Res. 1994, 29: 1-12.
  • /Vila R, Valenzuela L, Bello H, Cañigueral S, Montes M, Adzet T. Composition and antimicrobial activity of the essential oil of Peumus boldus leaves. Planta Med 1999, 65: 178-179.

Brezo

  • Referencias incluidas en la Bibliografía General.

Caléndula

  • Akihisa T, Yasukawa K, Oinuma H, Kasahara Y, Yamanouchi S, Takido M, Kumaki K, Tamura T. Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects. Phytochemistry 1996; 43 (6): 1255-1260.
  • Amirghofran Z, Azadbarkht M, Karimi MH. Evaluation of the immunomodulatory effects of five herbal plants. Journal of Ethnopharmacology 2000; 72: 167-172.
  • Bezakova L, Masterov I, Paulikora I, Psenak M. Inhibitory activity of isorrhammnetin glycosides from Calendula officinalis L. on the activity of lipooxygenase. Pharmazie 1996; 51:126-127.
  • Boucaud-Maitre Y, Algernon O, Raynaud J. Cytotoxic and antitumoral activity of Calendula officinales extract. Pharmazie 1998; 43: 220-221.
  • Chandran PK, Kuttan R. Effect of Calendula officinalis flower extract on acute phase proteins, antioxidante defense mechanisms and granuloma formation during termal burns. J Clin Biochem Nutr 2008; 43: 58-64.
  • Cordova C, Siqueira I, Netto C, Yunes R, Volpato A, Filho V, Curi-Pedrosa, Creczynski-Pasa T. Protective properties of butanolic extract of the Calendula officinalis L. (marigold) against lipid peroxidation of rat liver microsimes and action as free radical scavenger. Redox Rep 2002; 7 (2): 95-102.
  • Duran V, Matic M,Jovanové M, Mimica N, Gajinow Z, Poljacki M, Boza P. Results of the clinical examination of an ointment with marigold (Calendula officinalis) extract in the treatment of venous leg ulcers. Int J Tissue React 2005; 27 (3): 101-106.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final assessment report on Calendula officinalis L., flos - Revision 1. London: EMA. Doc. Ref.: EMA/HMPC/603409/2017. Adopted: 14/6/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final European Union herbal monograph on Calendula officinalis L., flos - Revision 1. London: EMA. Doc. Ref.: EMA/HMPC/437450/2017. Adopted: 22/6/2018.
  • Fronza M, Heinzmann B, Hamburger M, Laufer S, Merfort I. Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts. J Ethnopharmacol 2009; 126 (3): 463-467.
  • Fonseca YM, Catini CD, Vicentini FT, Nomizo A, Gerlach RF, Fonseca MJ. Protective effect of Calendula officinalis extract against UVB-induced oxidative stress in skin: evaluation of reduced glutathione levels and matrix metalloproteinase secretion. J Ethnopharmacol 2010; 127 (3): 596-601.
  • Fonseca YM, Catini CD, Vicentini FT, Cardoso JC, Cavalcanti De Alburquerque Junior RL, Vieria Fonseca MJ. Efficacy of marigold extract-loaded formulations against UV-induced oxidative stress. J Pharm Sci 2010. Doi 10.1002/jps.22438.
  • Fuchs J. Potentials and limitations of the natural antioxidants RRR-alpha-tocopherol, L-ascorbic acid and ß-carotene in cutaneous photoprotection. Free Radical Biol Med 1998. 25 (7): 848-873.
  • Fuchs SM, Schliemann-Willers S, Fischer TW, Elsner P. Protective effects of different marigold (Calendula officinalis L.) and rosemary cream preparations against sodium-lauryl-sulfate-induced irritant contact dermatitis. Skin Pharmacol Physiol 2005; 18: 195-200.
  • Guinot P, Gargadennec A, Valette G, Fruchier A, Andary C. Primary flavonoides in marigold dye: extraction, structure and involvement in the dyeing process. Phytochem. Anal. 2008; 19 (1): 46- 51.
  • Hamburger M, Adler S, Baumann D; Förg A, Weinreich B. Preparative purification of the major antiinflammatory triterpenoid ester from Marigold (Calendula officinalis). Fitoterapia 2003; 74 (4): 328-338.
  • Herold A, Cremer L, Calugaru A, Tamas V, Ionescu F, Manea S, Szegli G. Hydroalcoholic plant extracts with anti-inflammatory activity. Roum Arch Microbiol Immunol 2003; 62 (1-2):117-129.
  • Jiménez-Medina E, García-Lora A, Paco L, Algarra I, Collado A, Garrido F. A new extract of the plant Calendula officinalis producesa dual in vitro effect: cytotoxic anti-tumor activiy and lymphocyte activation. BMC Cancer 2006; 6: 119-132.
  • Kalvatchev Z, Walder R, Garzaro D. Anti-HIV activity of extract from Calendula officinales flowers. Biomedicine & Pharmacotherapy 1997; 51 (4): 176-180.
  • Kurkin VA, Sharova OV. Flavonoids from Calendula officinalis flowers. Chem Nat Compounds 2007; 43 (2): 216-217.
  • Neukirch H, D'Ambrosio M, Sosa S, Altinier G, Della Loggia R, Guerriero A. Improved antiinflammatory activity of three new terpenoids derived, by systematic chemical modifications,from the abundant triterpenes of the flowery plant Calendula officinalis. Chem Biodiv 2005; 2: 657-671.
  • Panahi Y, Sharif MR, Sharif A, Beiraghdar F, Zahiri Z, Amirchoopani G, et al. A randomized comparative trial on the therapeutic efficacy of topical aloe vera and Calendula officinalis on diaper dermatitis in children. Scientific World Journal. 2012; 2012: 810234. doi: 10.1100/2012/810234.
  • Patrick KFM, Kumar S, Edwardson PAD, Hutchinson JJ. Induction of vascularisation by an aqueous extract of the flowers of Calendula officinalis L. the European marigold. Phytomedicine 1996; 3 (1): 11-18.
  • Pazhohideh Z, Mohammadi S, Bahrami N, Mojab F, Abedi P, Maraghi E. The effect of Calendula officinalis versus metronidazole on bacterial vaginosis in women: A double-blind randomized controlled trial. J Adv Pharm Technol Res. 2018; 9 (1): 15-19. doi: 10.4103/japtr.JAPTR_305_17.
  • Pommier P, Gomez F, Sunyach MP D'Hombres A, Carrie C, Montbarbon X. Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. J Clin Oncol 2004; 22 (8): 1447-1453.
  • Pommier, P., Gomez, F., Sunyach, M. P., D'Hombres, A., Carrie, C., and Montbarbon, X. Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. J Clin Oncol 2004, 22(8):1447-1453.
  • Preethi KC, Kuttan R. Wound healing activity of flower extract of Calendula officinalis. J Basic Clin Physiol Pharmacol 2009; 20 (1): 73-79.
  • Schmidgall J, Schnetz E, Hensel A. Evidence for bioadhesive effects of polysaccharides and polysacchride-containing herbs in and ex vivo bioadhesion assay on buccal membranes. Planta Medica 2000; 66 (1): 48-53.
  • Stivala LA, Savio M, Cazzalini O, Pizzala R, Rehak L, Bianchi L, Vannini V, Prosperi E. Effect of ß-carotene on cell cycle progression of human fibroblast. Carcinogenesis 1996; 17 (11): 2395-2401.
  • Ukiya M, Akihisa T, Yasukawa K, Tokuda H, Suzuki t, Kimurai Y. Anti-inflammatory, anti-tumor-promoting, and cytotoxic activities of constituents of marigold (Calendula officinalis) flowers. J Nat Prod 2006; 69: 1692-1696.
  • Wagner H, Proksch A, Riess-Maurer I, Vollmar A, Odenthal S, Stuppner H, Jurcic K, Le Turdu M, Fang JN. Immunostimulating action of polysaccharides (heteroglycans) form higher plants. Arzneimittel-Forschung 1985; 35 (7): 1069-1075.
  • Woodall AA, Lee SWL, Weesie R, Jackson MJ, Britton G. Oxidation of carotenoids by free radicals: relationship between structure and reactivity. Biochim Biophys Acta 1997; 1336: 33-42.
  • Yoshikawa M, Murakami T, Kishi A, Kageura T, Matsuda H. Medicinal flowers. III) Marigold. (1): hypoglycaemic, gastric emptying inhibitory, and gastroprotective principles and new oleanetype triterpene oligolycosides, calendasaponins A, B, C and D, from Egyptian Calendula officinalis.
  • Zitterl-Eglseer K, Sosa S, Jurenitsch J, Schubert-Zsilavecz M, Della Loggia R, Tubaro A, Bertoldi M, Franz C. Anti-oedematous activities of the main triterpendiol esters of marigold (Calendula officinalis L.). Journal of Ethnopharmacology 1997; 57: 139-144.

Canela

  • Akilen R, Tsiami A, Devendra D, Robinson N. Cinnamon in glycaemic control: Systematic review and meta analysis. Clin Nutr 2012; 31: 609-615.
  • Akilen R, Tsiami A, Devendra D, Robinson N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet Med. 2010; 27 (10): 1159-67. doi: 10.1111/j.1464-5491.2010.03079.x.
  • Askari F, Rashidkhani B, Hekmatdoost A. Cinnamon may have therapeutic benefits on lipid profile, liver enzymes, insulin resistance, and high-sensitivity C-reactive protein in nonalcoholic fatty liver disease patients. Nutr Res. 2014; 34 (2): 143-8. doi: 10.1016/j.nutres.2013.11.005.
  • Beejmohun V, Peytavy-Izard M, Mignon C, Muscente-Paque D, Deplanque X, Ripoll C, et al. Acute effect of Ceylon cinnamon extract on postprandial glycemia: alpha-amylase inhibition, starch tolerance test in rats, and randomized crossover clinical trial in healthy volunteers. BMC Complement Altern Med. 2014; 14: 351. doi: 10.1186/1472-6882-14-351.
  • Costello RB, Dwyer JT, Saldanha L, Bailey RL, Merkel J, Wambogo E. Do cinnamon supplements have a role in glycemic control in type 2 diabetes? a narrative review. J Acad Nutr Diet. 2016; 116 (11): 1794-1802. doi:10.1016/j.jand.2016.07.015.
  • Crawford P, Thai C, Obholz J, Schievenin J, True M, Shah SA, et al. Assessment of the effect of lifestyle intervention plus water-soluble cinnamon extract on lowering blood glucose in pre-diabetics, a randomized, double-blind, multicenter, placebo controlled trial: study protocol for a randomized controlled trial. Trials. 2016; 17: 9. doi: 10.1186/s13063-015-1138-7.
  • Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009; 22 (5): 507-12.
  • Davis PA, Yokoyama W. Cinnamon intake lowers fasting blood glucose: meta-analysis. J Med Food 2011; 14: 884-889.
  • Leach MJ, Kumar S. Cinnamon for diabetes mellitus. Cochrane Database Syst Rev 2012; 9: CD007170.
  • Donald G, Barceloux MD. Cinnamon (Cinnamomum Species). Dis Mon 2009; 55: 327-335.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Cinnamomum verum J.S. Presl, cortex. London: EMA. Doc. Ref.: EMA/HMPC/246774/2009. Adopted: 10 May 2011.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Cinnamomum verum J.S. Presl, corticis aetheroleum. London: EMA. Doc. Ref.: EMA/HMPC/706229/2009. Adopted: 10 May 2011.
  • Gruenwald J, Freder J, Armbruester N. Cinnamon and health. Crit Rev Food Sci Nutr 2010; 50 (9): 822-34.
  • Gupta Jain S, Puri S, Misra A, Gulati S, Mani K. Effect of oral cinnamon intervention on metabolic profile and body composition of Asian Indians with metabolic syndrome: a randomized double -blind control trial. Lipids Health Dis. 2017; 16 (1): 113. doi: 10.1186/s12944-017-0504-8.
  • Kirkham S, Akilen R, Sharma S, Tsiami A. The potential of cinnamon to reduce blood glucose levels in patients with type 2 diabetes and insulin resistance. Diabetes Obes Metab 2009; 11 (12): 1100-13.
  • Kort DH, Lobo RA. Preliminary evidence that cinnamon improves menstrual cyclicity in women with polycystic ovary syndrome: a randomized controlled trial. Am J Obstet Gynecol. 2014; 211 (5): 487.e1-6. doi: 10.1016/j.ajog.2014.05.009.
  • Liu Y, Cotillard A, Vatier C, Bastard JP, Fellahi S, Stévant M, et al. Dietary supplement containing cinnamon, chromium and carnosine decreases fasting plasma glucose and increases lean mass in overweight or obese pre-diabetic subjects: a randomized, placebo-controlled trial. PLoS One. 2015; 10 (9): e0138646. doi: 10.1371/journal.pone.0138646.
  • Ríos JL, Francini F, Schinella GR. Natural products for the treatment of type 2 diabetes mellitus. Planta Med 2015; 81 (12-13): 975-94. doi: 10.1055/s-0035-1546131.
  • Rios JL, Schinella GR, Francini F. Productos naturales para el tratamiento de la diabetes (1): Mecanismos de acción. Revista de Fitoterapia 2016; 16 (1): 17-31.
  • Rios JL, Schinella GR, Francini F. Drogas vegetales para el tratamiento de la diabetes (II): ensayos clínicos. Revista de Fitoterapia 2016; 16 (2); 101-121.
  • Roussel AM, Hininger I, Benaraba R, Ziegenfuss TN, Anderson RA. Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J Am Coll Nutr. 2009; 28 (1): 16-21.
  • Sharma NK, Rani Y, Chauhan VS. Therapeutic Significance of Spices in daily dietary regimen: An Ayurvedic Perspective. En: Fresquet JL, Aguirre CP (Eds.). 5th European Colloquium on Ethnopharmacology - The cultural interbreeding in ethnopharmacology: from indigenous to scientific knowledges. Revista de Fitoterapia 2005; 5 (Supl 1): 256-257.
  • Singh G, Maurya S, deLampasona MP, Catalan C. A comparison of chemical, antioxidant and antimicrobial studies of cinnamon leaf and bark volatile oils, oleoresins and their constituents. Food Chem Toxicol 2007; 45: 1650-1661.
  • Unlu M, Ergene E, Unlu GV, Zeytinoglu HS, Vural N. Composition, antimicrobial activity and in vitro cytotoxicity of essential oil from Cinnamomum zeylanicum Blume (Lauraceae). Food Chem Toxicol 2010; 48: 3274-3280.

Cardamomo

  • Aghasi M, Ghazi-Zahedi S, Koohdani F, Siassi F, Nasli-Esfahani E, Keshavarz A, et al. The effects of green cardamom supplementation on blood glucose, lipids profile, oxidative stress, sirtuin-1 and irisin in type 2 diabetic patients: a study protocol for a randomized placebo-controlled clinical trial. BMC Complement Altern Med. 2018; 18 (1): 18. doi: 10.1186/s12906-017-2068-6.
  • Al-Bataina BA, Maslat AO, Al-Kofahil MM. Element analysis and biological studies on ten oriental spices using XRF and Ames test. J Trace Elem Med Biol 2003; 17: 85-90.
  • Al-Zuhair H, el-Sayeh B, Ameen HA, al-Shoora H. Pharmacological studies of cardamom oil in animals. Pharmacol Res 1996; 34: 79-82.
  • Azimi P, Ghiasvand R, Feizi A, Hariri M, Abbasi B. Effects of Cinnamon, Cardamom, Saffron, and Ginger Consumption on Markers of Glycemic Control, Lipid Profile, Oxidative Stress, and Inflammation in Type 2 Diabetes Patients. Rev Diabet Stud. 2014; 11 (3-4): 258-66. doi: 10.1900/RDS.2014.11.258.
  • Azimi P, Ghiasvand R, Feizi A, Hosseinzadeh J, Bahreynian M, Hariri M, Khosravi-Boroujeni H. Effect of cinnamon, cardamom, saffron and ginger consumption on blood pressure and a marker of endothelial function in patients with type 2 diabetes mellitus: A randomized controlled clinical trial. Blood Press. 2016; 25 (3): 133-40. doi: 10.3109/08037051.2015.1111020.
  • Bhaswant M, Poudyal H, Mathai ML, Ward LC, Mouatt P, Brown L. Green and Black Cardamom in a Diet-Induced Rat Model of Metabolic Syndrome. Nutrients. 2015; 7 (9): 7691-707. doi: 10.3390/nu7095360.
  • Bhattacharjee S, Rana T, Sengupta A. Inhibition of lipid peroxidation and enhancement of GST activity by cardamom and cinnamon during chemically induced colon carcinogenesis in Swiss albino mice. Asian Pac J Cancer Prev 2007; 8: 578-82.
  • EMA-HMPC. Public statement on the use of herbal medicinal products containing methyleugenol. Doc Ref: EMEA/HMPC/138363/2005.
  • Gilani AH, Jabeen Q, Khan AU, Shah AJ. Gut modulatory, blood pressure lowering, diuretic and sedative activities of cardamom. J Ethnopharmacol 2008; 115: 463-72.
  • Jamal A, Javed K, Aslam M, Jafri MA. Gastroprotective effect of cardamom, Elettaria cardamomum Maton. fruits in rats. J Ethnopharmacol 2006; 103: 149-53.
  • Kazemi S, Yaghooblou F, Siassi F, Rahimi Foroushani A, Ghavipour M, Koohdani F, et al. Cardamom supplementation improves inflammatory and oxidative stress biomarkers in hyperlipidemic, overweight, and obese pre-diabetic women: a randomized double-blind clinical trial. J Sci Food Agric. 2017; 97 (15): 5296-5301. doi: 10.1002/jsfa.8414.
  • Lawrence HA, Palombo EA. Activity of essential oils against Bacillus subtilis spores. J Microbiol Biotechnol 2009; 19: 1590-5.
  • Mahady GB, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR. In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother Res 2005; 19: 988-91.
  • Majdalawieh AF, Carr RI. In vitro investigation of the potential immunomodulatory and anti-cancer activities of black pepper (Piper nigrum) and cardamom (Elettaria cardamomum). J Med Food 2010, 13:371-81.
  • Marongiu B, Piras A, Porcedda S. Comparative analysis of the oil and supercritical CO2 extract of Elettaria cardamomum (L.) Maton. J Agric Food Chem 2004; 52: 6278-82.
  • Sengupta A, Ghosh S, Bhattacharjee S. Dietary cardamom inhibits the formation of azoxymethane-induced aberrant crypt foci in mice and reduces COX-2 and iNOS expression in the colon. Asian Pac J Cancer Prev 2005; 6(2): 118-22.
  • Vasudevan K, Vembar S, Veeraraghavan K, Haranath PS. Influence of intragastric perfusion of aqueous spice extracts on acid secretion in anesthetized albino rats. Indian J Gastroenterol 2000; 19: 53-6.
  • Verma SK, Jain V, Katewa SS. Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum). Indian J Biochem Biophys 2009, 46: 503-6.

Cardo Mariano

  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final European Union herbal monograph on Silybum marianum (L.) Gaertn., fructus. Doc. Ref.: EMA/HMPC/294187/2013. Adopted: 19/9/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final Assessment report on Silybum marianum (L.) Gaertn., fructus. Doc. Ref.: EMA/HMPC/294188/2013. Adopted: 19/9/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final list of references supporting the assessment of Silybum marianum (L.) Gaertn., fructus. Doc. Ref.: EMA/HMPC/278220/2015. Adopted: 19/9/2018.

Castañas de Indias

  • Aesculus hippocastanum (Horse chestnut). Monograph. Altern Med Rev. 2009; 14 (3): 278-83.
  • Bombardelli E, Morazzoni P, Griffini AA. Review: Aesculus hippocastanum L, Fitoterapia 67:483-511, 1996.
  • Bustamante SE, Torres R, Morales MA. Fitofármacos en el tratamiento de la insuficiencia venosa crónica. Revista de Fitoterapia 2009; 9 (1): 35-51.
  • Dickson S, Gallagher J, McIntyre L, Suter A, Tan J. An open study to assess the safety and efficacy of Aesculus hippocastanum tablets (Aesculaforce 50 mg) in the treatment of chronic venous insufficiency. J Herb Pharmacother. 2004; 4( 2): 19-32.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Aesculus hippocastanum L., cortex. London: EMA. Doc. Ref.: EMA/HMPC/354156/2011. Adopted: 22/5/2012.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Aesculus hippocastanum L., semen. London: EMA. Doc. Ref.: EMEA/HMPC/225319/2008. Adopted: 16/7/2009.
  • Ottillinger B, Greeske K. Rational therapy of chronic venous insufficiency--chances and limits of the therapeutic use of horse-chestnut seeds extract. BMC Cardiovasc Disord. 2001; 1: 5.
  • Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Nov 14;11:CD003230. doi: 10.1002/14651858.CD003230.pub4.
  • Simini, B. Horse-Chestnut Seed Extract for Chronic Venous Insufficiency, Lancet, 1996, 347: 1182-3.
  • Sirtori C.R. Aescin: Pharmacology, pharmacokinetics and therapeutic profile. Pharmacol Res. 2001, 44: 183-193.
  • Suter A, Bommer S, Rechner J. Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: a review of 5 clinical studies. Adv Ther. 2006; 23 (1): 179-90.

Cayena

  • Anónimo. Final report on the safety assessment of Capsicum annuum extract, Capsicum annuum fruit extract, Capsicum annuum resin, Capsicum annuum fruit powder, Capsicum frutescens fruit, Capsicum frutescens fruit extract, Capsicum frutescens resin, and capsaicin. Int J Toxicol 2007: 26 (Suppl 1): 3-106.
  • Bernstein JA, Davis BP, Picard JK, Cooper JP, Zheng S, Levin LS. A randomized, double-blind, parallel trial comparing capsaicin nasal spray with placebo in subjects with a significant component of nonallergic rhinitis. Ann Allergy Asthma Immunol. 2011; 107 (2): 171-8. doi: 10.1016/j.anai.2011.05.016
  • Bortolotti M, Porta S. Effect of red pepper on symptoms of irritable bowel syndrome: preliminary study. Dig Dis Sci. 2011; 56 (11): 3288-95. doi: 10.1007/s10620-011-1740-9.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Capsicum annuum L. var. minimum (Miller) Heiser and small fruited varieties of Capsicum frutescens L., fructus. London: EMA. Doc. Ref.: EMA/HMPC/674139/2013. Adopted: 5 May 2015.
  • Gagnier JJ, van Tulder MW, Berman B, Bombardier C. Herbal medicine for low back pain: a Cochrane review. Spine (Phila Pa 1976. 2007; 32(1): 82-92.
  • Robbins W. Clinical applications of capsaicinoides. Clin J Pain 2000; 16 (2 suppl): S86-89.

Cola de Caballo

  • Álvarez Padin P, Masferrer Serra J, Eneriz Calvo A, de Araoz Sánchez-Dopico P. Hipopotasemia extrema por cola de caballo. Galicia Clin 2010; 71 (2): 56-58.
  • Asgharikhatooni A, Bani S, Hasanpoor S, Mohammad Alizade S, Javadzadeh Y. The effect of equisetum arvense (horse tail) ointment on wound healing and pain intensity after episiotomy: a randomized placebo-controlled trial. Iran Red Crescent Med J. 2015; 17 (3):e25637. doi: 10.5812/ircmj.25637.
  • Cantoresi F, Sorgi P, Arcese A, Bidoli A, Bruni F, Carnevale C, et al. Improvement of psoriatic onychodystrophy by a water-soluble nail lacquer. J Eur Acad Dermatol Venereol. 2009; 23 (7): 832-4.
  • Carneiro DM, Freire RC, Honório TC, Zoghaib I, Cardoso FF, Tresvenzol LM, et al. Randomized, double-blind clinical trial to assess the acute diuretic effect of Equisetum arvense (field horsetail) in healthy volunteers. Evid Based Complement Alternat Med. 2014; 2014: 760683. doi: 10.1155/2014/760683.
  • Do Monte FH, dos Santos JG Jr, Russi M, Lanziotti VM, Leal LK, Cunha GM. Antinociceptive and anti-inflammatory properties of the hydroalcoholic extract of stems from Equisetum arvense L. in mice. Pharmacol Res 2004; 49 (3): 239-43.
  • Dragos D, Gilca M, Gaman L, Vlad A, Iosif L, Stoian I, Lupescu O. Phytomedicine in Joint Disorders. Nutrients. 2017;9(1). pii: E70. doi: 10.3390/nu9010070.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Equisetum arvense L., herba. London: EMA. Doc. Ref.: EMA/HMPC/278091/2015. 2 February 2016.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Species diureticae. London: EMA. Doc. Ref.: EMA/HMPC/224755/2016. Adopted: 21/7/2016.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Equisiti herba (Equisetum Stem). Exeter: ESCOP; 2018.
  • Gründemann C., Lengen K., Sauer B., Garcia-Käufer M., Zehl M., Huber R. Equisetum arvense (common horsetail) modulates the function of inflammatory immunocompetent cells. BMC Complement. Altern. Med. 2014;14:283 doi: 10.1186/1472-6882-14-283.
  • Guilherme dos Santos J Jr, Hoffmann Martins do Monte F, Marcela Blanco M, Maria do Nascimento Bispo Lanziotti V, Damasseno Maia F, Kalyne de Almeida Leal L. Cognitive enhancement in aged rats after chronic administration of Equisetum arvense L. with demonstrated antioxidant properties in vitro. Pharmacol Biochem Behav 2005; 81 (3): 593-600.
  • Mekhfi H, El Haouari M, Legssyer A, Bnouham M, Aziz M, Atmani F, et al. Platelet anti-aggregant property of some Moroccan medicinal plants. J Ethnopharmacol 2004; 94 (2-3): 317-22.
  • Mimica-Dukic N, Simin N, Cvejic J, Jovin E, Orcic D, Bozin B. Phenolic compounds in field horsetail (Equisetum arvense L.) as natural antioxidants. Molecules 2008; 13 (7): 1455-64.
  • Soleimani S, Azarbaizani FF, Nejati V. The effect of Equisetum arvense L. (Equisetaceae) in histological changes of pancreatic ß-cells in streptozotocin-induced diabetic in rats. Pak J Biol Sci 2007; 10 (23): 4236-40.
  • Oh H, Kim DH, Cho JH, Kim YC. Hepatoprotective and free radical scavenging activities of phenolic petrosins and flavonoids isolated from Equisetum arvense. J Ethnopharmacol 2004; 95 (2-3): 421-4.
  • Ozay Y, Ozyurt S, Guzel S, Cimbiz A, Olgun EG, Cayci MK. Effects of Equisetum arvense ointment on dermal wound healing in rats. Wounds Compend Clin Res Prac. 2010; 22 (10): 261–7.
  • Radulović N, Stojanović G, Palić R. Composition and antimicrobial activity of Equisetum arvense L. essential oil. Phytother Res 2006; 20 (1): 85-8.
  • Stajner D, Popović BM, Canadanović-Brunet J, Anackov G. Exploring Equisetum arvense L., Equisetum ramosissimum L. and Equisetum telmateia L. as sources of natural antioxidants. Phytother Res 2009; 23 (4): 546-50.

Comino

  • Allahghadri T, Rasooli I, Owlia P, Nadooshan MJ, Ghazanfari T, Taghizadeh M, Astaneh SD. Antimicrobial property, antioxidant capacity, and cytotoxicity of essential oil from cumin produced in Iran. J Food Sci 2010; 75: H54-61.
  • Chauhan PS, Satti NK, Suri KA, Amina M, Bani S. Stimulatory effects of Cuminum cyminum and flavonoid glycoside on Cyclosporine-A and restraint stress induced immune-suppression in Swiss albino mice. Chem Biol Interact 2010; 185: 66-72.
  • Dhandapani S, Subramanian R, Rajagopal S, Namasivayam N. Hypolipidemic effect of Cuminum cyminum L. on alloxan-induced diabetic rats. Pharmacol Res 2002; 46 (3): 251-255.
  • Gavanji S, Zaker SR, Nejad ZG, Bakhtari A, Bidabadi ES, Larki B. Comparative efficacy of herbal essences with amphotricin B and ketoconazole on Candida albicans in the in vitro condition. Integr Med Res. 2015; 4 (2): 112-118. doi: 10.1016/j.imr.2015.01.003.
  • Hajlaoui H, Mighri H, Noumi E, Snoussi M, Trabelsi N, Ksouri R, Bakhrouf A. Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: A high effectiveness against Vibrio spp. strains. Food Chem Toxicol 2010; 48: 2186-2192.
  • Jafari S, Sattari R, Ghavamzadeh S. Evaluation the effect of 50 and 100 mg doses of Cuminum cyminum essential oil on glycemic indices, insulin resistance and serum inflammatory factors on patients with diabetes type II: A double-blind randomized placebo-controlled clinical trial. J Tradit Complement Med. 2016; 7 (3): 332-338. doi: 10.1016/j.jtcme.2016.08.004.
  • Jagtap AG, Patil PB. Antihyperglycemic activity and inhibition of advanced glycation end product formation by Cuminum cyminum in streptozotocin induced diabetic rats. Food Chem Toxicol 2010; 48: 2030-6.
  • Kapoor LD. Handbook of Ayurvedic Medicinal Plants.CRC Press LLC., 2001, pp. 145.
  • Minooeianhaghighi MH, Sepehrian L, Shokri H. Antifungal effects of Lavandula binaludensis and Cuminum cyminum essential oils against Candida albicans strains isolated from patients with recurrent vulvovaginal candidiasis. J Mycol Med. 2017; 27 (1): 65-71. doi: 10.1016/j.mycmed.2016.09.002.
  • Nickavar B, Abolhasani FA. Screening of antioxidant properties of seven Umbelliferae fruits from Iran. Pak J Pharm Sci 2009; 22: 30-35.
  • Samani Keihan G, Gharib MH, Momeni A, Hemati Z, Sedighin R. A Comparison between the effect of Cuminum cyminum and vitamin e on the level of leptin, paraoxonase 1, hba1c and oxidized ldl in diabetic patients. Int J Mol Cell Med. 2016; 5 (4): 229-235.
  • Sharma NK, Rani Y, Chauhan VS. - Therapeutic Significance of Spices in daily dietary regimen: An Ayurvedic Perspective. En: Fresquet JL, Aguirre CP (Eds.). 5th European Colloquium on Ethnopharmacology - The cultural interbreeding in ethnopharmacology: from indigenous to scientific knowledges. Revista de Fitoterapia 2005; 5 (Supl 1): 256-257.
  • Shirke SS, Jagtap AG. Effects of methanolic extract of Cuminum cyminum on total serum cholesterol in ovariectomized rats. Indian J Pharmacol 2009; 41: 92-93.
  • Taghizadeh M, Memarzadeh MR, Abedi F, Sharifi N, Karamali F, Fakhrieh Kashan Z, et al. The effect of Cuminum cyminum L. plus lime administration on weight loss and metabolic status in overweight subjects: a randomized double-blind placebo-controlled clinical trial. Iran Red Crescent Med J. 2016; 18 (8): e34212.
  • Taghizadeh M, Memarzadeh MR, Asemi Z, Esmaillzadeh A. Effect of the Cuminum cyminum L. intake on weight loss, metabolic profiles and biomarkers of oxidative stress in overweight subjects: a randomized double-blind placebo-controlled clinical trial. Ann Nutr Metab. 2015;66(2-3):117-24. doi: 10.1159/000373896.
  • Zare R, Heshmati F, Fallahzadeh H, Nadjarzadeh A. Effect of cumin powder on body composition and lipid profile in overweight and obese women. Complement Ther Clin Pract. 2014; 20 (4): 297-301. doi: 10.1016/j.ctcp.2014.10.001.

Cúrcuma

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  • Alonso Osorio MJ, Allué Creus J. Fitosomas: un desarrollo tecnológico para mejorar la biodisponibilidad de los extractos vegetales. Revista de Fitoterapia 2015; 15 (2): 109-119.
  • Amro MS, Teoh SL, Norzana AG, Srijit D. The potential role of herbal products in the treatment of Parkinson's disease. Clin Ter. 2018; 169 (1): e23-e33. doi: 10.7417/T.2018.2050.
  • Chainani-Wu N, Madden E, Lozada-Nur F, Silverman S Jr. High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus. J Am Acad Dermatol. 2012; 66 (5): 752-60. doi: 10.1016/j.jaad.2011.04.022.
  • Chainani-Wu N, Silverman S Jr, Reingold A, Bostrom A, Mc Culloch C, Lozada-Nur F, et al. A randomized, placebo-controlled, double-blind clinical trial of curcuminoids in oral lichen planus. Phytomedicine 2007; 14: 437-446.
  • Daily JW, Yang M, Park S. Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Med Food. 2016; 19 (8): 717-29.
  • Demmers A, Korthout H, van Etten-Jamaludin FS, Kortekaas F, Maaskant JM. Effects of medicinal food plants on impaired glucose tolerance: A systematic review of randomized controlled trials. Diabetes Res Clin Pract. 2017; 131: 91-106. doi: 10.1016/j.diabres.2017.05.024.
  • Di Mario F, Cavallaro LG, Nouvenne A, Stefani N, Cavestro GM, Iori V et al. A curcumin-based 1-week triple therapy for eradication of Helicobacter pylori infection: something to learn from failure? Helicobacter 2007; 12: 238-243.
  • El-Moselhy MA, Taye A, Sharkawi SS, El-Sisi SF, Ahmed AF. The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids. Food Chem Toxicol. 2011; 49 (5): 1129-40. doi: 10.1016/j.fct.2011.02.004.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final European Union herbal monograph on Curcuma longa L., rhizoma - Revision 1. London: EMA. Doc. Ref.: EMA/HMPC/329755/2017. Publicación: 24/1/2019.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Draft assessment report on Curcuma longa L. (C. domestica Valeton), rhizome – Revision 1. London: EMA. Doc. Ref.: EMA/HMPC/749518/2016. Publicación: 8/12/2017.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Draft list of references supporting the assessment of Curcuma longa L. (C. domestica Valeton), rhizome – Revision 1. London: EMA. Doc. Ref.: EMA/434955/2017. Publicación: 8/12/2017.
  • Feng T, Wei Y, Lee RJ, Zhao L. Liposomal curcumin and its application in cancer. Int J Nanomedicine. 2017; 12: 6027-6044. doi: 10.2147/IJN.S132434.
  • Forouzanfar F, Hosseinzadeh H. Medicinal herbs in the treatment of neuropathic pain: a review. Iran J Basic Med Sci. 2018 Apr;21(4):347-358. doi: 10.22038/IJBMS.2018.24026.6021.
  • Gilhotra N, Dhingra D. GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice. Brain Res 2010; 1352: 167-175.
  • Haroyan A, Mukuchyan V, Mkrtchyan N, Minasyan N, Gasparyan S, Sargsyan A, et al. Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study. BMC Complement Altern Med. 2018; 18 (1): 7. doi: 10.1186/s12906-017-2062-z.
  • Hu RW, Carey EJ, Lindor KD, Tabibian JH. Curcumin in hepatobiliary disease: pharmacotherapeutic properties and emerging potential clinical applications. Ann Hepatol. 2017; 16 (6): 835-841. doi: 10.5604/01.3001.0010.5273. Ann Hepatol. 2017; 16 (6): 835-841. doi: 10.5604/01.3001.0010.5273.
  • Jamwal R. Bioavailable curcumin formulations: A review of pharmacokinetic studies in healthy volunteers. J Integr Med. 2018 Jul 4. pii: S2095-4964(18)30077-3. doi: 10.1016/j.joim.2018.07.001.
  • Jiang S, Han J, Li T, Xin Z, Ma Z, Di W, et al. Curcumin as a potential protective compound against cardiac diseases. Pharmacol Res. 2017; 119: 373-383. doi: 10.1016/j.phrs.2017.03.001.
  • Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev 2009; 14: 141-153.
  • Khayat S, Fanaei H, Kheirkhah M, Moghadam ZB, Kasaeian A, Javadimehr M. Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial. Complement Ther Med. 2015; 23 (3): 318-24. doi: 10.1016/j.ctim.2015.04.001.
  • Kuptniratsaikul V, Thanakhumtorn S, Chinswangwatanakul P, Wattanamongkonsil L, Thamlikitkul V. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med 2009; 15: 891-897.
  • Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ. Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis. Br J Sports Med. 2018; 52 (3): 167-175. doi: 10.1136/bjsports-2016-097333.
  • Moragrega I, Ríos JL. Depresión e inflamación: potencial terapéutico de curcumina. Revista de Fitoterapia 2018; 18 (1): 35-51.
  • Neto FC, Marton LT, de Marqui SV, Lima TA, Barbalho SM. Curcuminoids from Curcuma longa: new adjuvants for the treatment of Crohn's disease and ulcerative colitis? Crit Rev Food Sci Nutr. 2018:1-36. doi: 10.1080/10408398.2018.
  • Panahi Y, Khalili N, Sahebi E, Namazi S, Karimian MS, Majeed M, Sahebkar A. Antioxidant effects of curcuminoids in patients with type 2 diabetes mellitus: a randomized controlled trial. Inflammopharmacology. 2017; 25 (1): 25-31. doi: 10.1007/s10787-016-0301-4.
  • Panahi Y, Khalili N, Sahebi E, Namazi S, Reiner Ž, Majeed M, et al. Curcuminoids modify lipid profile in type 2 diabetes mellitus: A randomized controlled trial. Complement Ther Med. 2017; 33: 1-5. doi: 10.1016/j.ctim.2017.05.006.
  • Peddada KV, Brown A, Verma V, Nebbioso M. Therapeutic potential of curcumin in major retinal pathologies. Int Ophthalmol. 2018 Feb 5. doi: 10.1007/s10792-018-0845-y.
  • Pinsornsak P, Niempoog S. The efficacy of Curcuma Longa L. extract as an adjuvant therapy in primary knee osteoarthritis: a randomized control trial. J Med Assoc Thai. 2012; 95 Suppl 1: S51-8.
  • Rasyid A, Rahman AR, Jaalam K, Lelo A. Effect of different curcumin dosages on human gall bladder. Asia Pac J Clin Nutr 2002; 11: 314-318.
  • Ringman JM, Frautschy SA, Teng E, Begum AN, Bardens J, Beigi M, et al. Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study. Alzheimers Res Ther. 2012; 4 (5): 43. doi: 10.1186/alzrt146.
  • Sarris J. Herbal medicines in the treatment of psychiatric disorders: 10-year updated review. Phytother Res. 2018 Mar 25. doi: 10.1002/ptr.6055.
  • Simadibrata M, Halimkesuma CC, Suwita BM. Efficacy of curcumin as adjuvant therapy to induce or maintain remission in ulcerative colitis patients: an evidence-based clinical review. Acta Med Indones. 2017; 49 (4): 363-368. 9.
  • Sindhu S, Chempakam B, Leela NK, Suseela Bhai R. Chemoprevention by essential oil of turmeric leaves (Curcuma longa L.) on the growth of Aspergillus flavus and aflatoxin production. Food Chem Toxicol. 2011; 49 (5): 1188-92. doi: 10.1016/j.fct.2011.02.014.
  • Soleimani V, Sahebkar A, Hosseinzadeh H. Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review. Phytother Res. 2018 Feb 26. doi: 10.1002/ptr.6054.
  • Srivastava S, Fatima M, Mondal AC. Important medicinal herbs in Parkinson's disease pharmacotherapy. Biomed Pharmacother. 2017; 92: 856-863. doi: 10.1016/j.biopha.2017.05.137.
  • Srivastava S, Saksena AK, Khattri S, Kumar S, Dagur RS. Curcuma longa extract reduces inflammatory and oxidative stress biomarkers in osteoarthritis of knee: a four-month, double-blind, randomized, placebo-controlled trial. Inflammopharmacology. 2016; 24 (6): 377-388.
  • Taylor RA, Leonard MC. Curcumin for inflammatory bowel disease: a review of human studies. Altern Med Rev. 2011; 16 (2): 152-6.
  • Wickenberg J, Ingemansson SL, Hlebowicz J. Effects of Curcuma longa (turmeric) on postprandial plasma glucose and insulin in healthy subjects. Nutr J 2010; 9: 43.
  • Zhao Y, Chen ZY. Roles of spicy foods and their bioactive compounds in management of hypercholesterolemia. J Agric Food Chem. 2018 Aug 22;66(33):8662-8671. doi: 10.1021/acs.jafc.8b02975.

Curry Madrás

  • No se han encontrado datos.

Diente de León

  • Alkofahi AS, Abdul-Razzak KK, Alzoubi KH, Khabour OF. Report - screening of the anti-hyperglycemic activity of some medicinal plants of Jordan. Pak J Pharm Sci. 2017; 30 (3): 907-912.
  • Clare BA, Conroy RS, Spelman K. The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day. J Altern Complement Med 2009; 15 (8): 929-34. doi: 10.1089/acm.2008.0152.
  • Clare BA, Conroy RS, Spelman K. The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day. J Altern Complement Med 2009; 15 (8): 929-34. doi: 10.1089/acm.2008.0152.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Taraxacum officinale Weber ex Wigg., folium. London: EMA. Doc. Ref.: EMA/HMPC/579636/2008. Adopted: 12/11/2009.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Taraxacum officinale Weber ex Wigg., radix cum herba. London: EMA. Doc. Ref: EMA/HMPC/212895/2008. Adopted: 12/11/2009.
  • Gamboa-Gómez CI, Rocha-Guzmán NE, Gallegos-Infante JA, Moreno-Jiménez MR, Vázquez-Cabral BD, González-Laredo RF. Plants with potential use on obesity and its complications. EXCLI J. 2015;14:809-31.
  • González-Castejón M, Visioli F, Rodriguez-Casado A. Diverse biological activities of dandelion. Nutr Rev. 2012; 70 (9): 534-47. doi: 10.1111/j.1753-4887.2012.00509.x.
  • Martinez M, Poirrier P, Chamy R, Prüfer D, Schulze-Gronover C, Jorquera L, et al. Taraxacum officinale and related species-An ethnopharmacological review and its potential as a commercial medicinal plant. J Ethnopharmacol. 2015;169:244-62.
  • Minciullo PL, Calapai G, Miroddi M, Mannucci C, Chinou I, Gangemi S, et al. Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - part 4: Solidago virgaurea-Vitis vinifera. Contact Dermatitis. 2017; 77 (2): 67-87. doi: 10.1111/cod.12807.
  • Schütz K, Carle R, Schieber A. Taraxacum--a review on its phytochemical and pharmacological profile. J Ethnopharmacol. 2006;107(3):313-23.
  • Wirngo FE, Lambert MN, Jeppesen PB. The physiological effects of dandelion (Taraxacum officinale) in type 2 diabetes. Rev Diabet Stud. 2016; 13 (2-3): 113-131. doi: 10.1900/RDS.2016.13.113.

Enebro Bayas

  • Bais S, Gill NS, Rana N, Shandil S. A phytopharmacological review on a medicinal plant: Juniperus communis. Int Sch Res Notices. 2014 Nov 11;2014:634723. doi: 10.1155/2014/634723.
  • Cavaleiro C, Pinto E, Gonçalves MJ, Salgueiro L. Antifungal activity of Juniperus essential oils against dermatophyte, Aspergillus and Candida strains. J Appl Microbiol 2006; 100 (6): 1333-8.
  • Emami SA, Asili J, Mohagheghi Z, Hassanzadeh MK. Antioxidant activity of leaves and fruits of Iranian conifers. Evid Based Complement Alternat Med 2007; 4 (3): 313-9.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Juniperus communis L., pseudo-fructus. London: EMA. Doc. Ref.: EMA/HMPC/441929/2008. Adopted: 12 November 2009.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Juniperus communis L., aetheroleum. London: EMA. Doc. Ref.: EMA/HMPC/12402/2010. Adopted: 25 November 2010.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Species diureticae. London: EMA. Doc. Ref.: EMA/HMPC/224755/2016. Adopted: 21/7/2016.
  • Klančnik A, Zorko Š, Toplak N, Kovač M, Bucar F, Jeršek B, Smole Možina S. Antiadhesion activity of juniper (Juniperus communis L.) preparations against Campylobacter jejuni evaluated with PCR-based methods. Phytother Res. 2018; 32 (3): 542-550. doi: 10.1002/ptr.6005.
  • Miceli N, Trovato A, Dugo P, Cacciola F, Donato P, Marino A, et al. Comparative analysis of flavonoid profile, antioxidant and antimicrobial activity of the berries of Juniperus communis L. var. communis and Juniperus communis L. var. saxatilis Pall. from Turkey. J Agric Food Chem 2009; 57 (15): 6570-7.
  • Pepeljnjak S, Kosalec I, Kalodera Z, Blazević N. Antimicrobial activity of juniper berry essential oil (Juniperus communis L., Cupressaceae). Acta Pharm 2005; 55 (4): 417-22.
  • Tavares WR, Seca AML. The current status of the pharmaceutical potential of Juniperus L. metabolites. Medicines (Basel). 2018;5(3). pii: E81. doi: 10.3390/medicines5030081.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Yarnell E. Botanical medicines for the urinary tract. World J Urol. 2002;20(5):285-93.

Eneldo

  • Saghafi N, Karjalian M, Ghazanfarpour M, Khorsand I, Rakhshandeh H, Mirteimouri M, et al. The effect of a vaginal suppository formulation of dill (Anethum graveolens) in comparison to clotrimazole vaginal tablet on the treatment of vulvovaginal candidiasis. J Obstet Gynaecol. 2018; 38 (7): 985-988. doi: 10.1080/01443615.2018.1432578.
  • Yung-Shin Shyu, Jau-Tien Lin, Yuan-Tsung Chang, Chia-Jung Chiang, Deng-Jye Yang Evaluation of antioxidant ability of ethanolic extract from dill (Anethum graveolens L.) flower 2009 Food Chemistry 2009; 115: 515-521.

Equinácea

  • Agencia Española de Medicamentos y Productos Sanitarios. Ficha técnica Echinamed Junior comprimidos. Marzo 2015.
  • Ardjomand-Woelkart K, Bauer R. Review and assessment of medicinal safety data of orally used echinacea preparations. Planta Med. 2016;82(1-2):17-31. doi: 10.1055/s-0035-1558096.
  • Barnes J, Anderson LA, Gibbons S, Phillipson JD. Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.) Moench): A review of their chemistry, pharmacology and clinical properties. J Pharm Pharmacol 2005; 57: 929-954.
  • Bauer R. New knowledge regarding the effect and effectiveness of Echinacea purpurea extracts. Wien Med Wochenschr 2002; 152(15-16): 407-411.
  • Chen Y, Fu T, Tao T, Yang J, Chang Y, Wang M, et al. Macrophage activating effects of new alkamides from the roots of Echinacea species. J Nat Prod 2005; 68: 773-776.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Echinacea angustifolia DC., radix. London: EMA. Doc. Ref.: EMA/HMPC/688216/2008. Adopted: 27 March 2012.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final European Union herbal monograph on Echinacea pallida (Nutt.) Nutt., radix - Revision 1. Doc. Ref.:EMA/HMPC/737380/2018. Adopted: 14/8/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final assessment report on Echinacea pallida (Nutt.) Nutt., radix - Revision 1. Doc. Ref.: EMA/HMPC/737379/2017. Adopted: 14/8/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final list of references supporting the assessment of Echinacea pallida (Nutt.) Nutt., radix - Revision 1. Doc. Ref.: EMA/HMPC/737378/2018. Adopted: 14/8/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Echinacea purpurea (L.) Moench, radix. London: EMA. Doc. Ref.: EMA/HMPC/424583/2016. Published: 11/8/2017.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final assessment report on Echinacea purpurea (L.) Moench, radix – Revision 1. London: EMA. Doc. Ref.: EMA/HMPC/424584/2016. Published: 11/8/2017.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Echinacea purpurea (L.) Moench, herba recens. London: EMA. Doc. Ref.: EMA/HMPC/48704/2014 Corr. Adopted: 24 November 2015.
  • ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Echinacea pallidae radix (Pale coneflower root). Exeter: ESCOP; 2018.
  • Gertsch J, Schoop R, Kuenzle U, Suter A. Echinacea alkylamides modulate TNF-alpha gene expression via cannabinoid receptor CB2 and multiple signal transduction pathways. FEBS Lett 2004; 577: 563-569.
  • Goel V, Chang C, Slama J, Barton R, Bauer R, Gahler R, et al. Echinacea stimulates macrophage function in the lung and spleen of normal rats. J Nutr Biochem 2002; 13: 487-492.
  • Goel V, Chang C, Slama JV, Barton R, Bauer R, Gahler R, et al. Alkylamides of Echinacea purpurea stimulate alveolar macrophage function in normal rats. Int Immunopharmacol 2002; 2: 381-387.
  • Griffin AS, Cabot P, Wallwork B, Panizza B. Alternative therapies for chronic rhinosinusitis: A review. Ear Nose Throat J. 2018; 97(3):E25-E33.
  • Jawad M, Schoop R, Suter A, Klein P, Eccles R. Perfil de eficacia y seguridad de Echinacea purpurea en la prevención de episodios de resfriado común: estudio clínico aleatorizado, doble ciego y controlado con placebo. Revista de Fitoterapia 2013; 13 (2): 125-135.
  • Karsch-Völk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, Linde K. Echinacea for preventing and treating the common cold. Cochrane Database Syst Rev 2014 ; (2): CD000530. doi: 10.1002/14651858.CD000530.pub3.
  • Matthias A, Addison RS, Agnew LL, Bone KM, Watson K, Lehmann RP. Comparison of Echinacea alkylamide pharmacokinetics between liquid and tablet preparations. Phytomedicine 2007; 14: 587-590.
  • Matthias A, Banbury L, Bone KM, Leach DN, Lehmann RP. Echinacea alkylamides modulate induced immune responses in T-cells. Fitoterapia 2008; 79: 53-58.
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  • O'Neil J, Hughes S, Lourie A, Zweifler J. Effects of echinacea on the frequency of upper respiratory tract symptoms: a randomized, double-blind, placebo-controlled trial. Ann Allergy Asthma Immunol. 2008; 100 (4): 384-8. doi: 10.1016/S1081-1206(10)60603-5.
  • Oláh A, Szabó-Papp J, Soeberdt M, Knie U, Dähnhardt-Pfeiffer S, Abels C, et al. Echinacea purpurea-derived alkylamides exhibit potent anti-inflammatory effects and alleviate clinical symptoms of atopic eczema. J Dermatol Sci 2017; 88 (1) :67-77. doi: 10.1016/j.jdermsci.2017.05.015.
  • Pleschka S, Stein M, Schoop R, Hudson JB. Actividad de un extracto de equinácea purpúrea frente a los virus de la gripe H1N1, H5N1 y H7N7. Revista de Fitoterapia 2009; 9 (2): 115-124.
  • Rauš K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. Curr Ther Res Clin Exp 2015; 77: 66-72. doi: 10.1016/j.curtheres.2015.04.001.
  • Ross SM. Echinacea purpurea: A proprietary extract of Echinacea purpurea is shown to be safe and effective in the prevention of the common cold. Holist Nurs Pract. 2016; 30(1):54-7. doi: 10.1097/HNP.0000000000000130.
  • Shah SA, Sander S, White CM, Rinaldi M, Coleman CI. Evaluation of Echinacea for the prevention and treatment of the common cold: a meta-analysis. Lancet Infect Dis. 2007;7:473-80.
  • Sharifi-Rad M, Mnayer D, Morais-Braga MFB, Carneiro JNP, Bezerra CF, Coutinho HDM, et al. Echinacea plants as antioxidant and antibacterial agents: From traditional medicine to biotechnological applications. Phytother Res. 2018; 32(9):1653-1663. doi: 10.1002/ptr.6101.
  • Sharma M, Anderson SA, Schoop R, Hudson JB. Induction of multiple pro-inflammatory cytokines by respiratory viruses and reversal by standardized Echinacea, a potent antiviral herbal extract. Antiviral Res 2009; 83: 165-170.
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  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36. Zhai Z, Liu Y, Wu L, Senchina DS, Wurtele ES, Murphy PA, et al. Enhancement of innate and adaptive immune functions by multiple Echinacea species. J Med Food 2007; 10: 423-434.

Espino Blanco

  • Asher GN, Viera AJ, Weaver MA, Dominik R, Caughey M, Hinderliter AL. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial. BMC Complement Altern Med. 2012;12:26. doi: 10.1186/1472-6882-12-26.
  • Brenyo A, Aktas MK. Review of complementary and alternative medical treatment of arrhythmias. Am J Cardiol. 2014;113(5):897-903. doi: 10.1016/j.amjcard.2013.11.044.
  • Cañigueral S. Vanaclocha B. Interés terapéutico de la sumidad de espino blanco. Revista de Fitoterapia 2000; 1 (2): 85-93.
  • Chatterjee SS, Koch E, Jaggy H, Krzeminski T . In vitro and in vivo studies on the cardioprotective action of oligomeric procyanidins in a Crataegus extract of leaves and blooms. Arzneimittelforschung 1997; 47 (7): 821-5.
  • Chen ZY, Zhang ZS, Kwan KY, Zhu M, Ho WK, Huang Y. Endothelium-dependent relaxation induced by hawthorn extract in rat mesenteric artery. Life Sci 1998; 63 (22): 1983-91.
  • Ciplea AG, Richter KD. The protective effect of Allium sativum and crataegus on isoprenaline-induced tissue necroses in rats. Arzneimittelforschung 1988; 38 (11): 1583-92.
  • Dalli E. La sumidad florida de espino albar en la terapéutica cardiovascular. Revista de Fitoterapia 2004; 4 (1): 5-21.
  • Dalli E. Treatment of estable angina pectoris with hawthorn (Crataegus oxyacantha). Heart 2002; 87 (suppl I) A9.
  • Dalli E. Nuevas aportaciones sobre efectos del espino blanco (Crataegus sp.) en patología cardiovascular. Revista de Fitoterapia 2009; 9 (Supl 1): 69-74.
  • Dalli E, Colomer E, Tormos MC, Cosín-Sales J, Milara J, Esteban E, et al. Crataegus laevigata decreases neutrophil elastase and has hypolipidemic effect: a randomized, double-blind, placebo-controlled trial. Phytomedicine. 2011; 18 (8-9): 769-75. doi: 10.1016/j.phymed.2010.11.011.
  • Degenring FH, Suter A, Weber M, Saller R. A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan) in the treatment of patients with congestive heart failure NYHA II. Phytomedicine. 2003; 10 (5): 363-9.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Crataegus spp., folium cum flore. London: EMA. Doc. Ref.: EMA/HMPC/159075/2014. Adopted: 5 April 2016.
  • Forster A, Forster K, Buhring M et al. Crataegus for moderately reduced left ventricular ejection fraction. Ergospirometric monitoring study with 72 patients in a double-blind comparison with placebo. Munch Med Wochenschr 1994; 136: S21-6.
  • Habs M. Prospective, comparative cohort studies and their contribution to the benefit assessments of therapeutic options: heart failure treatment with and without "hawthorn" special extract WS 1442. Forsch Komplementärmed Klass Naturheilkd 2004; 11(Suppl. 1): 36–39.
  • Holubarsch CJF, Colucci WS, Eha J. Benefit-risk assessment of Crataegus axtract WS 1442: an evidence-based review. Am J Cardiovasc Drugs. 2018;18(1):25-36. doi: 10.1007/s40256-017-0249-9.
  • Holubarsch CJ, Colucci WS, Meinertz T, Gaus W, Tendera M; Survival and prognosis: Investigation of Crataegus Extract WS 1442 in CHF (SPICE) trial study group. The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure: the SPICE trial. Eur J Heart Fail. 2008; 10 (12): 1255-63. doi: 10.1016/j.ejheart.2008.10.004.
  • Leuchtgens H. Crataegus Special Extract WS 1442 in NYHA II heart failure. A placebo controlled randomized double-blind study. Fortschr Med 1993; 111:352-4.
  • Loew D. Phytogenic drugs in heart diseases exemplified by Crataegus. Wien Med Wochenschr 1999;149 (8-10): 226-8.
  • Muller A, Linke W, Klaus W. Crataegus extract blocks potassium currents in guinea pig ventricular cardiac myocytes. Planta Med 1999; 65 (4): 335-9.
  • Nabavi SF, Habtemariam S, Ahmed T, Sureda A, Daglia M, Sobarzo-Sánchez E, et al. Polyphenolic composition of Crataegus monogyna Jacq.: from chemistry to medical applications. Nutrients. 2015;7(9):7708-28. doi: 10.3390/nu7095361.
  • Pittler MH, Schmidt K, Ernst E. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am J Med 2003; 114: 665–674.
  • Rastogi S, Pandey MM, Rawat AK. Traditional herbs: a remedy for cardiovascular disorders. Phytomedicine. 2016; 23 (11):1082-9. doi: 10.1016/j.phymed.2015.10.012.
  • Schmidt U, Kuhn U, Ploch M, Hübner WD. Efficacy of the Hawthorn (Crataegus) preparation LI 132 in 78 patients with chronic congestive Herat failure defined as NYHA functional class II. Phytomedicine 1994; 1: 17-24.
  • Tauchert M, Gildor A, Lipinski J. High-dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure. Herz 1999; 24 (6):465-74; discussion 475. Published erratum appears in Herz 1999; 24 (7): 586.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36. Walker AF. Promising hypotensive effect of hawthorn extract: a randomized, double-blind, pilot study of mild essential hypertension. Phytotherapy Res 2002; 16: 48–54.
  • Weikl A, Assmus KD, Neukum-Schmidt A, Schmitz J. Zapfe, G.; et al. Crataegus Special Extract WS 1442. Assessment of objective effectiveness in patients with heart failure (NYHA II). Fortschr Med 1996; 114: 291-6.
  • Zapfe jun G. Clinical efficacy of crataegus extract WS 1442 in congestive heart failure NYHA class II. Phytomedicine. 2001; 8 (4): 262-6.
  • Zick SM, Gillespie B, Aaronson KD. The effect of Crataegus oxycantha special extract WS 1442 on clinical progression in patients with mild to moderate symptoms of heart failure. Eur J Heart Fail. 2008; 10 (6): 587-93. doi: 10.1016/j.ejheart.2008.04.008.
  • Zorniak M, Szydlo B, Krzeminski TF. Crataegus special extract WS 1442: up-to-date review of experimental and clinical experiences. J Physiol Pharmacol. 2017;68(4):521-526.

Eucalipto

  • Abouzid SF, Ahmed OM, Ahmed RR, Mahmoud A, Abdella E, Ashour MB. Antihyperglycemic Effect of Crude Extracts of Some Egyptian Plants and Algae. J Med Food. 2014 Jan 9.
  • Ben-Arye E, Dudai N, Eini A, Torem M, Schiff E, Rakover Y. Treatment of upper respiratory tract infections in primary care: a randomized study using aromatic herbs. Evid Based Complement Alternat Med 2011; 2011: 690346. doi: 10.1155/2011/690346.
  • Dhakad AK, Pandey VV, Beg S, Rawat JM, Singh A. Biological, medicinal and toxicological significance of Eucalyptus leaf essential oil: a review. J Sci Food Agric. 2018;98(3):833-848. doi: 10.1002/jsfa.8600.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Eucalyptus globulus Labill., folium. London: EMA. Doc. Ref.: EMA/HMPC/892618/2011. Adopted: 15 April 2013.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Eucalyptus globulus Labill., Eucalyptus polybractea R.T. Baker and/or Eucalyptus smithii R.T. Baker, aetheroleum. London: EMA. Doc. Ref.: EMA/HMPC/307781/2012. Adopted: 25 March 2014.
  • Gray AM, Flatt PR. Antihyperglycemic actions of Eucalyptus globulus (Eucalyptus) are associated with pancreatic and extra-pancreatic effects in mice. Journal of Nutrition 1998; 128 (12): 2319-23.
  • Higgins C, Palmer A, Nixon R. Eucalyptus oil: contact allergy and safety. Contact Dermatitis. 2015;72(5):344-6. doi: 10.1111/cod.12376.
  • Khan R, Islam B, Akram M, Shakil S, Ahmad A, Ali SM, Siddiqui M, Khan AU. Antimicrobial activity of five herbal extracts against multi drug resistant (MDR) strains of bacteria and fungus of clinical origin. Molecules 2009; 14 (2): 586-97. doi: 10.3390/molecules14020586.
  • Salari MH, Amine G, Shirazi MH, Hafezi R, Mohammadypour M. Antibacterial effects of Eucalyptus globulus leaf extract on pathogenic bacteria isolated from specimens of patients with respiratory tract disorders. Clin Microbiol Infect. 2006 Feb;12(2):194-6.
  • Seol GH, Kim KY. Eucalyptol and its role in chronic diseases. Adv Exp Med Biol. 2016; 929:389-398.
  • Sugimoto K, Hosotani T, Kawasaki T, Nakagawa K, Hayashi S, Nakano Y, Inui H, Yamanouchi T. Eucalyptus leaf extract suppresses the postprandial elevation of portal, cardiac and peripheral fructose concentrations after sucrose ingestion in rats. J Clin Biochem Nutr 2010; 46 (3): 205-11. doi: 10.3164/jcbn.09-93.
  • Tohidpour A, Sattari M, Omidbaigi R, Yadegar A, Nazemi J. Antibacterial effect of essential oils from two medicinal plants against Methicillin-resistant Staphylococcus aureus (MRSA). Phytomedicine. 2010 Feb;17(2):142-5. doi: 10.1016/j.phymed.2009.05.007.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Worth H, Dethlefsen U. Patients with asthma benefit from concomitant therapy with cineole: a placebo-controlled, double-blind trial. J Asthma. 2012;49(8):849-53.
  • Worth H, Schacher C, Dethlefsen U. Concomitant therapy with cineole (Eucalyptole) reduces exacerbations in COPD: a placebo-controlled double-blind trial. Respir Res. 2009;10:69.

Ginkgo

  • Aziz TA, Hussain SA, Mahwi TO, Ahmed ZA, Rahman HS, Rasedee A. The efficacy and safety of Ginkgo biloba extract as an adjuvant in type 2 diabetes mellitus patients ineffectively managed with metformin: a double-blind, randomized, placebo-controlled trial. Drug Des Devel Ther. 2018;12:735-742. doi: 10.2147/DDDT.S157113.
  • Behl T, Kotwani A. Chinese herbal drugs for the treatment of diabetic retinopathy. J Pharm Pharmacol. 2017; 69 (3): 223-235. doi: 10.1111/jphp.12683.
  • Bhidayasiri R, Jitkritsadakul O, Friedman JH, Fahn S. Updating the recommendations for treatment of tardive syndromes: A systematic review of new evidence and practical treatment algorithm. J Neurol Sci. 2018 Jun 15; 389: 67-75. doi: 10.1016/j.jns.2018.02.010.
  • Charemboon T, Jaisin K. Ginkgo biloba for prevention of dementia: a systematic review and meta-analysis. J Med Assoc Thai 2015; 98 (5): 508-13.
  • Chen X, Hong Y, Zheng P. Efficacy and safety of extract of Ginkgo biloba as an adjunct therapy in chronic schizophrenia: A systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis. Psychiatry Res 2015; 228 (1): 121-7. doi: 10.1016/j.psychres.2015.04.026.
  • Cicero AFG, Fogacci F, Banach M. Botanicals and phytochemicals active on cognitive decline: The clinical evidence. Pharmacol Res. 2017 Dec 28. pii: S1043-6618(17)30783-1. doi: 10.1016/j.phrs.2017.12.029.
  • Deng H, Adams CE. Traditional Chinese medicine for schizophrenia: A survey of randomized trials. Asia Pac Psychiatry. 2017; 9 (1). doi: 10.1111/appy.12265.
  • Doozandeh A, Yazdani S. Neuroprotection in Glaucoma. J Ophthalmic Vis Res. 2016; 11 (2): 209-20. doi: 10.4103/2008-322X.183923.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Ginkgo biloba L., folium. Ref. Doc. EMA/HMPC/321097/2012. Adopted: 28 January 2015.
  • Fan Y, Jin X, Man C, Gong D. Does adjuvant treatment with Ginkgo biloba to statins have additional benefits in patients with dyslipidemia? Front Pharmacol. 2018;9:659. doi: 10.3389/fphar.2018.00659.
  • Gauthier S, Schlaefke S. Efficacy and tolerability of Ginkgo biloba extract EGb 761 in dementia: a systematic review and meta-analysis of randomized placebo-controlled trials. Clin Interv Aging. 2014; 9: 2065–2077. doi: 10.2147/CIA.S72728.
  • Gavrilova SI, Preuss UW, Wong JW, Hoerr R, Kaschel R, Bachinskaya N; GIMCIPlus Study Group. Efficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial. Int J Geriatr Psychiatry. 2014;29(10):1087-95. doi: 10.1002/gps.4103.
  • González Rodríguez B, Vanaclocha B. Potencial terapéutico del extracto de Ginkgo biloba (EGb) en pacientes con esquizofrenia. Revista de Fitoterapia 2017; 17 (1): 37-51.
  • Herrschaft H, Nacu A, Likhachev S, Sholomov I, Hoerr R, Schlaefke S. Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg. J Psychiatr Res. 2012; 46 (6): 716-23. doi: 10.1016/j.jpsychires.2012.03.003.
  • Hoenders HJR, Bartels-Velthuis AA, Vollbehr NK, Bruggeman R, Knegtering H, de Jong JTVM. Natural Medicines for Psychotic Disorders: A Systematic Review. J Nerv Ment Dis. 2018; 206 (2): 81-101. doi: 10.1097/NMD.0000000000000782.
  • Hyde AJ, May BH, Dong L, Feng M, Liu S, Guo X, Zhang AL, Lu C, Xue CC. Herbal medicine for management of the behavioural and psychological symptoms of dementia (BPSD): A systematic review and meta-analysis. J Psychopharmacol. 2017; 31 (2): 169-183. doi: 10.1177/0269881116675515.
  • Ihl R, Tribanek M, Bachinskaya N. Baseline neuropsychiatric symptoms are effect modifiers in Ginkgo biloba extract (EGb 761) treatment of dementia with neuropsychiatric features. Retrospective data analyses of a randomized controlled trial. J Neurol Sci. 2010; 299 (1-2): 184-7. doi: 10.1016/j.jns.2010.08.033.
  • Izzo AA, Ernst E. Interactions between herbal medicines and prescribed drugs: a systematic review. Drugs 2001; 61 (15): 2163-75.
  • Kang JM, Lin S. Ginkgo biloba and its potential role in glaucoma. Curr Opin Ophthalmol. 2018; 29 (2): 116-120. doi: 10.1097/ICU.0000000000000459.
  • Kellermann AJ, Kloft C. Is there a risk of bleeding associated with standardized Ginkgo biloba extract therapy? A systematic review and meta-analysis. Pharmacotherapy. 2011; 31 (5): 490-502. doi: 10.1592/phco.31.5.490.
  • Laver K, Dyer S, Whitehead C, Clemson L, Crotty M. Interventions to delay functional decline in people with dementia: a systematic review of systematic reviews. BMJ Open. 2016; 6 (4): e010767. doi: 10.1136/bmjopen-2015-010767. Review. Erratum in: BMJ Open. 2017 Jun 7; 7 (5): e010767corr1.
  • Lewis JE, Melillo AB, Tiozzo E, Chen L, Leonard S, Howell M, Diaz J, et al. A double-blind, randomized clinical trial of dietary supplementation on cognitive and immune functioning in healthy older adults. BMC Complement Altern Med. 2014 Feb 4;14:43. doi: 10.1186/1472-6882-14-43. Erratum in: BMC Complement Altern Med. 2014;14:332.
  • Loskutova E, O'Brien C, Loskutov I, Loughman J. Nutritional supplementation in the treatment of glaucoma: a systematic review. Surv Ophthalmol. 2018 Oct 5. pii: S0039-6257(18)30100-0. doi: 10.1016/j.survophthal.2018.09.005.
  • Mahmoudian-Sani MR, Hashemzadeh-Chaleshtori M, Asadi-Samani M, Yang Q. Ginkgo biloba in the treatment of tinnitus: An updated literature review. Int Tinnitus J. 2017; 21 (1): 58-62. doi: 10.5935/0946-5448.20170011.
  • Mi XS, Zhong JX, Chang RC, So KF. Research advances on the usage of traditional Chinese medicine for neuroprotection in glaucoma. J Integr Med. 2013; 11 (4): 233-40. doi: 10.3736/jintegrmed2013037.
  • Morales MA, Bustamante S, Gallardo R. Aplicaciones clínicas del extracto de la hoja de Ginkgo biloba. Revista de Fitoterapia 2000, 1 (2): 95-105.
  • Nash KM, Shah ZA. Current perspectives on the beneficial role of Ginkgo biloba in neurological and cerebrovascular disorders. Integr Med Insights. 2015; 10: 1-9. doi: 10.4137/IMI.S25054. eCollection 2015.
  • Oskouei DS, Rikhtegar R, Hashemilar M, Sadeghi-Bazargani H, Sharifi-Bonab M, Sadeghi-Hokmabadi E, et al. The effect of Ginkgo biloba on functional outcome of patients with acute ischemic stroke: a double-blind, placebo-controlled, randomized clinical trial. J Stroke Cerebrovasc Dis. 2013; 22 (8): e557-63. doi: 10.1016/j.jstrokecerebrovasdis.2013.06.010.
  • Sarris J. Herbal medicines in the treatment of psychiatric disorders: 10-year updated review. Phytother Res. 2018 Mar 25. doi: 10.1002/ptr.6055.
  • Savaskan E, Mueller H, Hoerr R, von Gunten A, Gauthier S. Treatment effects of Ginkgo biloba extract EGb 761 on the spectrum of behavioral and psychological symptoms of dementia: meta-analysis of randomized controlled trials. Int Psychogeriatr. 2017 Sep 21: 1-9. doi: 10.1017/S1041610217001892.
  • Singh SK, Barreto GE, Aliev G, Echeverria V. Ginkgo biloba as an alternative medicine in the treatment of anxiety in dementia and other psychiatric disorders. Curr Drug Metab. 2017; 18 (2): 112-119. doi: 10.2174/1389200217666161201112206.
  • Soares-Weiser K, Rathbone J, Ogawa Y, Shinohara K, Bergman H. Miscellaneous treatments for antipsychotic-induced tardive dyskinesia. Cochrane Database Syst Rev. 2018 Mar 19; 3: CD000208. doi: 10.1002/14651858.CD000208.pub2.
  • Sokolova L, Hoerr R, Mishchenko T. Treatment of Vertigo: A Randomized, Double-Blind Trial Comparing Efficacy and Safety of Ginkgo biloba Extract EGb 761 and Betahistine. Int J Otolaryngol. 2014;2014:682439. doi: 10.1155/2014/682439.
  • Spiegel R, Kalla R, Mantokoudis G, Maire R, Mueller H, Hoerr R, et al. Ginkgo biloba extract EGb 761 alleviates neurosensory symptoms in patients with dementia: a meta-analysis of treatment effects on tinnitus and dizziness in randomized, placebo-controlled trials. Clin Interv Aging. 2018;13:1121-1127. doi: 10.2147/CIA.S157877.
  • Stoddard GJ, Archer M, Shane-McWhorter L, Bray BE, Redd DF, Proulx J, et al. Ginkgo and warfarin interaction in a large veterans administration population. AMIA Annu Symp Proc. 2015 Nov 5;2015:1174-83.
  • Ströhle A, Schmidt DK, Schultz F, Fricke N, Staden T, Hellweg R, et al. Drug and exercise treatment of alzheimer disease and mild cognitive impairment: a systematic review and meta-analysis of effects on cognition in randomized controlled trials. Am J Geriatr Psychiatry. 2015; 23 (12): 1234-1249. doi: 10.1016/j.jagp.2015.07.007.
  • Vaes LP, Chyka PA. Interactions of warfarin with garlic, ginger, ginkgo, or ginseng: nature of the evidence. Annals of Pharmacotherapy 2000; 34 (12): 1478-82.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Vellas B, Coley N, Ousset PJ, Berrut G, Dartigues JF, Dubois B, et al. Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial. Lancet Neurol 2012; 11 (10): 851-9. doi: 10.1016/S1474-4422(12)70206-5.
  • Weinmann S, Roll S, Schwarzbach C, Vauth C, Willich SN. Effects of Ginkgo biloba in dementia: systematic review and meta-analysis. BMC Geriatrics 2010; 10: 14. doi:10.1186/1471-2318-10-14.
  • Wightman EL. Potential benefits of phytochemicals against Alzheimer's disease. Proc Nutr Soc. 2017; 76 (2): 106-112. doi: 10.1017/S0029665116002962.
  • Yang G, Wang Y, Sun J, Zhang K, Liu J. Ginkgo biloba for mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis of randomized controlled trials. Curr Top Med Chem. 2016; 16 (5): 520-8.
  • Yuan Q, Wang CW, Shi J, Lin ZX. Effects of Ginkgo biloba on dementia: An overview of systematic reviews. J Ethnopharmacol. 2017; 195: 1-9. doi: 10.1016/j.jep.2016.12.005.
  • Zhang HF, Huang LB, Zhong YB, Zhou QH, Wang HL, Zheng GQ, Lin Y. An overview of systematic reviews of ginkgo biloba extracts for mild cognitive impairment and dementia. Front Aging Neurosci. 2016; 8: 276. doi: 10.3389/fnagi.2016.00276.
  • Zheng W, Xiang YQ, Ng CH, Ungvari GS, Chiu HF, Xiang YT. Extract of Ginkgo biloba for tardive dyskinesia: meta-analysis of randomized controlled trials. Pharmacopsychiatry. 2016; 49 (3): 107-11. doi: 10.1055/s-0042-102884.
  • Zuo W, Yan F, Zhang B, Li J, Mei D. Advances in the studies of Ginkgo biloba leaves extract on aging-related diseases. Aging Dis. 2017; 8 (6): 812-826. doi: 10.14336/AD.2017.0615.

Grama Raíz

  • Atmani F, Sadki C, Aziz M, Mimouni M, Hacht B. Cynodon dactylon extract as a preventive and curative agent in experimentally induced nephrolithiasis. Urol Res 2009; 37 (2): 75-82.
  • Biswas TK, Pandit S, Chakrabarti S, Banerjee S, Poyra N, Seal T. Evaluation of Cynodon dactylon for wound healing activity. J Ethnopharmacol. 2017;197:128-37.
  • Garjani A, Afrooziyan A, Nazemiyeh H, Najafi M, Kharazmkia A, Maleki-Dizaji N. Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats. BMC Complement Altern Med 2009; 9: 28.
  • Jarald EE, Joshi SB, Jain DC. Antidiabetic activity of aqueous extract and non polysaccharide fraction of Cynodon dactylon Pers. Indian J Exp Biol 2008; 46 (9): 660-7.
  • Khajavi Rad A, Hadjzadeh MA, Rajaei Z, Mohammadian N, Valiollahi S, Sonei M. The beneficial effect of cynodon dactylon fractions on ethylene glycol-induced kidney calculi in rats. Urol J. 2011;8(3):179-84.
  • Pal D. Evaluation of CNS activities of aerial parts of Cynodon dactylon Pers. in mice. Acta Pol Pharm 2008; 65 (1): 37-43.
  • Sindhu G, Ratheesh M, Shyni GL, Helen A. Inhibitory effects of Cynodon dactylon L. on inflammation and oxidative stress in adjuvant treated rats. Immunopharmacol Immunotoxicol 2009; 31 (4): 647-53.

Hibisco

  • Abat JK, Kumar S, Mohanty A. Ethnomedicinal, Phytochemical and ethnopharmacological aspects of four medicinal plants of malvaceae used in Indian traditional medicines: a review. Medicines (Basel). 2017; 4 (4). pii: E75. doi: 10.3390/medicines4040075.
  • Adegunloye BJ, Omoniyi JO, Owolabi OA, Ajagbonna OP, Sofola OA, Coker HA. Mechanisms of the blood pressure lowering effect of the calyx extract of Hibiscus sabdariffa in rats. Afr J Med Med Sci 1996; 25 (3): 235-8.
  • Ali MB, Mohamed AH, Salih WM et al. Effect of an aqueous extract of hibiscus sabdariffa calyces on the gastrointestinal tract, Fitoterapia, 1991; 42 (2): 457-9.
  • Ali MB, Salih WM, Mohamed AH et al. Investigation of the antispasmodic potential of Hibiscus sabdariffa calyces. J Ethnopharmacol 1991; 31 (2): 249-257.
  • Asgary S, Soltani R, Zolghadr M, Keshvari M, Sarrafzadegan N. Evaluation of the effects of roselle (Hibiscus sabdariffa L.) on oxidative stress and serum levels of lipids, insulin and hs-CRP in adult patients with metabolic syndrome: a double-blind placebo-controlled clinical trial. J Complement Integr Med. 2016; 13 (2): 175-80. doi: 10.1515/jcim-2015-0030.
  • Aziz Z, Wong SY, Chong NJ. Effects of Hibiscus sabdariffa L. on serum lipids: a systematic review and meta-analysis. J Ethnopharmacol. 2013; 150 (2): 442-50. doi: 10.1016/j.jep.2013.09.042. Epub 2013 Oct 10.
  • Blanquer Hernández A, Herrera-Arellano A, Zamilpa Alvarez A, Olivar Rivas T, Martínez García M. Interés de la flor de hibisco en problemas cardiovasculares. Revista de Fitoterapia 2009; 9 (1): 25-33.
  • Carvajal-Zarrabal O, Barradas-Dermitz DM, Orta-Flores Z, Margaret Hayward-Jones P, Nolasco-Hipólito C, Aguilar-Uscanga MG, et al. Hibiscus sabdariffa L., roselle calyx, from ethnobotany to pharmacology. J Exp Pharmacol 2012; 4: 25–39. doi: 10.2147/JEP.S27974
  • Chukwu Nwachukwu D, Ikemefuna Aneke E, Fidelis Obika L, Zuada Nwachukwu N. Effects of aqueous extract of Hibiscus sabdariffa on the renin-angiotensin-aldosterone system of Nigerians with mild to moderate essential hypertension: A comparative study with lisinopril. Indian J Pharmacol 2015; 47 (5): 540–545. doi: 10.4103/0253-7613.165194
  • Dafallah AA, Al-Mustafa Z. Investigation of the anti-inflammatory activity of Acacia nilotica and Hibiscus sabdariffa. Am J Chin Med 1996; 24 (3-4): 263-9.
  • El Saadany SS, Sitohy MZ, Labib SM. Biochemical dynamics and hypocholesterolemic action of Hibiscus sabdariffa (Karkade), Nahrung 1991; 35 (6): 567-576.
  • Gamboa-Gómez CI, Rocha-Guzmán NE, Gallegos-Infante JA, Moreno-Jiménez MR, Vázquez-Cabral BD, González-Laredo RF. Plants with potential use on obesity and its complications. EXCLI J. 2015; 14: 809-31. doi: 10.17179/excli2015-186.
  • Hernández-Pérez F, Herrera-Arellano A. Tratamiento de la hipercolesterolemia con Hibiscus sabadariffa, Ensayo clínico aleatorizado controlado. Rev Med Inst Mex Seguro Soc. 2011; 49 (5): 469-80.
  • Herranz-López M, Olivares-Vicente M, Encinar JA, Barrajón-Catalán E, Segura-Carretero A, Joven J, et al. Multi-targeted molecular effects of Hibiscus sabdariffa polyphenols: an opportunity for a global approach to obesity. Nutrients. 2017; 9 (8). pii: E907. doi: 10.3390/nu9080907.
  • Herrera-Arellano A, Miranda-Sánchez J, Avila-Castro P, Herrera-Alvarez S, Jiménez-Ferrer JE, Zamilpa A, et al. Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial. Planta Med. 2007; 73 (1): 6-12.
  • Hopkins AL, Lamm MG, Funk J, Ritenbaugh C. Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: a comprehensive review of animal and human studies. Fitoterapia 2013; 85: 84–94. doi: 10.1016/j.fitote.2013.01.003.
  • Kafeshani M, Entezari MH, Karimian J, Pourmasoumi M, Maracy MR, Amini MR, et al. A comparative study of the effect of green tea and sour tea on blood pressure and lipid profile in healthy adult men. ARYA Atheroscler. 2017; 13 (3): 109-116.
  • Kuriyan R, Kumar R, Rajendran R, Kurpad AV. An evaluation of the hypolipidemic effect of an extract of Hibiscus Sabdariffa leaves in hyperlipidemic Indians: a double blind, placebo controlled trial. BMC Complement Altern Med. 2010; 10: 27. doi: 10.1186/1472-6882-10-27
  • Lin TL, Lin HH, Chen CC, Lin MC, Chou MC, Wang CJ. Hibiscus sabdariffa extract reduces serum cholesterol in men and women. Nutrition Research 2007; 27 (3): 140–145.
  • McKay DL, Chen CY, Saltzman E, Blumberg JB. Hibiscus sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. J Nutr. 2010; 140 (2): 298-303. doi: 10.3945/jn.109.115097. Epub 2009 Dec 16.
  • Mozaffari-Khosravi H, Jalali-Khanabadi BA, Afkhami-Ardekani M, Fatehi F, Noori-Shadkam M. The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes. J Hum Hypertens. 2009; 23 (1):48-54. doi: 10.1038/jhh.2008.100.Muller BM, Franz G. Chemical structure and biological activity of polysaccharides from Hibiscus sabdariffa. Planta Med 1992; 58 (1): 60-7.
  • Nwachukwu DC, Aneke EI, Obika LF, Nwachukwu NZ. Effects of aqueous extract of Hibiscus sabdariffa on the renin-angiotensin-aldosterone system of Nigerians with mild to moderate essential hypertension: A comparative study with lisinopril. Indian J Pharmacol. 2015; 47 (5): 540-5. doi: 10.4103/0253-7613.165194.
  • Onyenekwe PC, Ajani EO, Ameh DA, Gamaniel KS. Antihypertensive effect of roselle (Hibiscus sabdariffa) calyx infusion in spontaneously hypertensive rats and a comparison of its toxicity with that in Wistar rats. Cell Biochem Funct 1999; 17 (3): 199-206.
  • Riaz G, Chopra R. A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L. Biomed Pharmacother. 2018; 102: 575-586. doi: 10.1016/j.biopha.2018.03.023.
  • Rodríguez-Pérez C, Segura-Carretero A, Del Mar Contreras M. Phenolic compounds as natural and multifunctional anti-obesity agents: A review. Crit Rev Food Sci Nutr. 2017 Nov 20:1-18. doi: 10.1080/10408398.2017.1399859
  • Sabzghabaee AM, Ataei E, Kelishadi R, Ghannadi A, Soltani R, Badri S, et al. Effect of Hibiscus sabdariffa Calices on Dyslipidemia in Obese Adolescents: A Triple-masked Randomized Controlled Trial. Mater Sociomed 2013; 25 (2): 76–79. doi: 10.5455/msm.2013.25.76-79.
  • Sahebkar A, Serban MC, Gluba-Brzózka A, Mikhailidis DP, Cicero AF, Rysz J, et al. Lipid-modifying effects of nutraceuticals: An evidence-based approach. Nutrition. 2016 Nov-Dec;32(11-12):1179-92. doi: 10.1016/j.nut.2016.04.007.
  • Tseng TH, Kao ES, Chu CY, Chou FP, Lin Wu HW, Wang CJ. Protective effects of dried flower extracts of Hibiscus sabdariffa L. against oxidative stress in rat primary hepatocytes. Food Chem Toxicol 1997; 35 (12): 1159-64
  • Wang CJ; Wang JM; Lin WL; Chu CY; Chou FP; Tseng TH. Protective effect of Hibiscus anthocyanins against tert-butyl hydroperoxide-induced hepatic toxicity in rats. Food Chem Toxicol 2000; 38 (5): 411-6.

Hierba Luisa

  • Bahramsoltani R, Nia MM, Najafi F, Rahimi R. Efficacy and tolerability of phytomedicines in multiple sclerosis patients: A Review. CNS Drugs. 2017;31(10):867-889. doi: 10.1007/s40263-017-0466-4.
  • Bahramsoltani R, Rostamiasrabadi P, Shahpiri Z, Marques AM, Rahimi R, Farzaei MH. Aloysia citrodora Paláu (Lemon verbena): A review of phytochemistry and pharmacology. J Ethnopharmacol. 2018; 222:34-51. doi: 10.1016/j.jep.2018.04.021.
  • Buchwald-Werner S, Naka I, Wilhelm M, Schütz E, Schoen C, Reule C. Effects of lemon verbena extract (Recoverben) supplementation on muscle strength and recovery after exhaustive exercise: a randomized, placebo-controlled trial. J Int Soc Sports Nutr. 2018;15:5. doi: 10.1186/s12970-018-0208-0.

Hierbabuena

  • Ayaz M, Sadiq A, Junaid M, Ullah F, Subhan F, Ahmed J. Neuroprotective and anti-aging potentials of essential oils from aromatic and medicinal plants. Front Aging Neurosci. 2017; 9: 168. doi: 10.3389/fnagi.2017.00168.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Mentha x piperita L. aetheroleum. London: EMEA. Doc. Ref. EMEA/HMPC/349466/2006. Adopted: 31/10/2007.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Mentha x piperita L., folium. Draft. London: EMA. Doc Ref: EMA/HMPC/572705/2014. Adopted: 23/2/2017.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Menthae piperitae folium (Peppermint leaf). Exeter: ESCOP; 2019.
  • Grigoleit HG, Grigoleit P. Pharmacology and preclinical pharmacokinetics of peppermint oil. Phytomedicine. 2005; 12 (8): 612-6.
  • Grigoleit HG, Grigoleit P. Gastrointestinal clinical pharmacology of peppermint oil. Phytomedicine. 2005; 12 (8):607-11.
  • Grigoleit HG, Grigoleit P. Peppermint oil in irritable bowel syndrome. Phytomedicine. 2005; 12 (8): 601-6.
  • Keifer D, Ulbricht C, Abrams TR, Basch E, Giese N, Giles M, et al. Peppermint (Mentha piperita): an evidence-based systematic review by the Natural Standard Research Collaboration. J Herb Pharmacother. 2007; 7 (2): 91-143.
  • McKay DL, Blumberg JB, A review of the bioactivity and potential health benefits of Peppermint tea (Mentha piperita L.). Phytother Res 2006; 20(8): 619-633.
  • Pasha H, Behmanesh F, Mohsenzadeh F, Hajahmadi M, Moghadamnia AA. Study of the effect of mint oil on nausea and vomiting during pregnancy. Iran Red Crescent Med J. 2012; 14 (11): 727-30. doi: 10.5812/ircmj.3477.
  • Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am J Gastroenterol. 1998; 93 (7): 1131-5.
  • Riachi LG, De Maria CA. Peppermint antioxidants revisited. Food Chem. 2015; 176: 72-81. doi: 10.1016/j.foodchem.2014.12.028.
  • Tayarani-Najaran Z, Talasaz-Firoozi E, Nasiri R, Jalali N, Hassanzadeh M. Antiemetic activity of volatile oil from Mentha spicata and Mentha × piperita in chemotherapy-induced nausea and vomiting. Ecancermedicalscience. 2013; 7: 290. doi: 10.3332/ecancer.2013.290.
  • Thompson Coon J, Ernst E. Systematic review: herbal medicinal products for non-ulcer dyspepsia. Aliment Pharmacol Ther. 2002; 16 (10): 1689-99.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.

Hinojo

  • Akha O, Rabiei K, Kashi Z, Bahar A, Zaeif-Khorasani E, Kosaryan M, et al. The effect of fennel (Foeniculum vulgare) gel 3% in decreasing hair thickness in idiopathic mild to moderate hirsutism, A randomized placebo controlled clinical trial. Caspian J Intern Med. 2014; 5 (1): 26-9.
  • Alexandrovich I, Rakovitskaya O, Kolmo E, Sidorova T, Shushunov S. The effect of fennel (Foeniculum Vulgare) seed oil emulsion in infantile colic: a randomized, placebo-controlled study. Altern Ther Health Med. 2003; 9 (4): 58-61.
  • European Medicines Agency (EMEA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Foeniculum vulgare Miller subsp. vulgare var. vulgare, aetheroleum. London: EMA. Doc. Ref.: EMEA/HMPC/263292/2006. Adopted: 5 July 2007.
  • European Medicines Agency (EMEA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Foeniculum vulgare Miller subsp. vulgare var. dulce, fructus. London: EMA. Doc. Ref.: EMEA/HMPC/137428/2006. Adopted: 6 August 2007.
  • European Medicines Agency (EMEA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Foeniculum vulgare Miller subsp. vulgare var. vulgare (Miller) Thellung, fructus. . London: EMA. Doc. Ref.: EMEA/HMPC/263293/2006. Adopted: 6 August 2007.
  • European Medicines Agency (EMEA) - Committee on Herbal Medicinal Products (HMPC). Public statement on the use of herbal medicinal products containing estragole. London: EMA. Doc Ref: EMEA/HMPC/137212/2005. Adopted: 23 November 2005.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Foeniculum aetheroleum (Bitter-fennel fruit oil). Exeter: ESCOP; 2019.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Foeniculum fructose (Fennel fruit). Exeter: ESCOP; 2019.
  • Ghazanfarpour M, Amini E, Khadivzadeh T, Babakhanian M, Nouri B, Rakhshandeh H, et al. The effect of short-term treatment with fennel on bone density in postmenopausal women: a randomized controlled trial. J Menopausal Med. 2017; 23 (2): 124-130. doi: 10.6118/jmm.2017.23.2.124.
  • Ghazanfarpour M, Mohammadzadeh F, Shokrollahi P, Khadivzadeh T, Najaf Najafi M, Hajirezaee H, et al. Effect of Foeniculum vulgare (fennel) on symptoms of depression and anxiety in postmenopausal women: a double-blind randomized controlled trial. J Obstet Gynaecol. 2018; 38 (1): 121-126. doi: 10.1080/01443615.2017.1342229.
  • Ghazanfarpour M, Shokrollahi P, Khadivzadeh T, Baharian Sharghi N, Mirzaii Najmabadi K, Babakhanian M, et al. Effect of Foeniculum vulgare (fennel) on vaginal atrophy in postmenopausal women: A double-blind, randomized, placebo-controlled trial. Post Reprod Health. 2017; 23 (4): 171-176. doi: 10.1177/2053369117733629.
  • Harb T, Matsuyama M, David M, Hill R. Infant colic-what works: a systematic review of interventions for breastfed infants. J Pediatr Gastroenterol Nutr. 2016;62:668-86. doi: 10.1097/MPG.0000000000001075.
  • Javidnia K, Dastgheib L, Mohammadi Samani S, Nasiri A. Antihirsutism activity of Fennel (fruits of Foeniculum vulgare) extract. A double-blind placebo controlled study. Phytomedicine. 2003; 10 (6-7): 455-8.
  • Mohebbi-Kian E., Mohammad-Alizadeh-Charandabi S., Bekhradi R. Efficacy of fennel and combined oral contraceptive on depot medroxyprogesterone acetate-induced amenorrhea: A randomized placebo-controlled trial. Contraception. 2014;90(4):440–446. doi: 10.1016/j.contraception.2014.05.001.
  • Perry R, Hunt K, Ernst E. Nutritional supplements and other complementary medicines for infantile colic: a systematic review. Pediatrics. 2011; 127 (4): 720-33. doi: 10.1542/peds.2010-2098.
  • Portincasa P, Bonfrate L, Scribano ML, Kohn A, Caporaso N, Festi D, et al. Curcumin and fennel essential oil improve symptoms and quality of life in patients with irritable bowel syndrome. J Gastrointestin Liver Dis. 2016; 25 (2): 151-7. doi: 10.15403/jgld.2014.
  • Saghafi N, Ghazanfarpour M, Khadivzadeh T, Babakhanian M, Afiat M. The effect of Foeniculum vulgare (fennel) on body composition in postmenopausal women with excess weight: a double-blind randomized placebo-controlled trial. J Menopausal Med. 2017 Dec;23(3):166-171. doi: 10.6118/jmm.2017.23.3.166.
  • Savino F, Cresi F, Castagno E, Silvestro L, Oggero R. A randomized double-blind placebo-controlled trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and Melissa officinalis (ColiMil) in the treatment of breastfed colicky infants. Phytother Res. 2005;19 (4): 335-40.
  • Yaralizadeh M, Abedi P, Najar S, Namjoyan F, Saki A. Effect of Foeniculum vulgare (fennel) vaginal cream on vaginal atrophy in postmenopausal women: A double-blind randomized placebo-controlled trial. Maturitas. 2016; 84: 75-80. doi: 10.1016/j.maturitas.2015.11.005.

Hipérico

  • Albert D, Zündorf I, Dingermann T, Müller WE, Steinhilber D, Werz O. Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxigenase. Biochem Pharmacol 2002; 64: 1767-1775.
  • Apaydin EA, Maher AR, Shanman R, Booth MS, Miles JN, Sorbero ME, Hempel S. A systematic review of St. John's wort for major depressive disorder. Syst Rev. 2016; 5 (1):148. doi: 10.1186/s13643-016-0325-2.
  • Avila C, Whitten D, Evans S. The safety of St John's wort (Hypericum perforatum) in pregnancy and lactation: A systematic review of rodent studies. Phytother Res. 2018;32(8):1488-1500. doi: 10.1002/ptr.6099.
  • Avato P, Raffo F, Guglielmi G, Vitali C, Rosato A. Extracts from St John's wort and their antimicrobial activity. Phytother Res 2004; 18: 230-232.
  • Bilia AR, Gallori S, Vincieri FF. St John's wort and depression: efficacy, safety and tolerability-an update. Life Sci 2002; 70: 3077-3096.
  • Borrelli F, Izzo AA. Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations. AAPS J 2009; 11: 710-727.
  • Di YM, Li CG, Xue CC, Zhou SF. Clinical drugs that interact with St. John's wort and implication in drug development. Curr Pharm Des 2008; 14: 1723-1742.
  • Chrubasik-Hausmann S, Vlachojannis J, McLachlan AJ. Understanding drug interactions with St John's wort (Hypericum perforatum L.): impact of hyperforin content. J Pharm Pharmacol. 2018 Feb 7. doi: 10.1111/jphp.12858.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Hypericum perforatum L., herba (well-established medicinal use). London: EMA. Doc. Ref.: EMA/HMPC/101304/2008. Adopted: 12 November 2009.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Hypericum perforatum L., herba (traditional use) Draft. London: EMA. Doc. Ref.: EMA/188804/2017. Adopted: 30/01/2018.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs, The Scientific Foundation for Herbal Medicinal Products. Online series. Hyperci herba (St. John’s Wort). Exeter: ESCOP; 2018.
  • Gastpar M. Hypericum extract WS 5570 for depression--an overview. Int J Psychiatry Clin Pract. 2013; 17 Suppl 1: 1-7. doi: 10.3109/13651501.2013.813554.
  • Griffith TN, Varela-Nallar L, Dinamarca MC, Inestrosa NC. Neurobiological effects of Hyperforin and its potential in Alzheimer's disease therapy. Curr Med Chem 2010; 17: 391-406.
  • Kasper S, Gastpar M, Möller HJ, Müller WE, Volz HP, Dienel A, Kieser M. Better tolerability of St. John's wort extract WS 5570 compared to treatment with SSRIs: a reanalysis of data from controlled clinical trials in acute major depression. Int Clin Psychopharmacol. 2010; 25 (4): 204-13.
  • Linde K. St. John's wort - an overview. Forsch Komplementmed 2009; 16: 146-155.
  • Linde K, Berner MM, Kriston L. St John's wort for major depression. Cochrane Database Syst Rev 2008; (4): CD000448.
  • Linde K, Knüppel I. Large-scale observational studies of Hypericum extracts in patients with depressive disorders - a systematic review. Phytomedicine 2005; 12: 148-157.
  • Linde K, Kriston L, Rücker G, Jamil S, Schumann I, Meissner K, et al. Efficacy and acceptability of pharmacological treatments for depressive disorders in primary care: systematic review and networkmeta-analysis. Ann Fam Med. 2015; 13 (1): 69-79. doi: 10.1370/afm.1687.
  • Mazandarani M, Yassaghi S, Rezaei MB, Mansourian AR, Ghaemi EO. Ethnobotany and antibacterial activities of two endemic species of Hypericum in north-east of Iran. Asian J Plant Sci 2007; 6: 354-358.
  • Ng QX, Venkatanarayanan N, Ho CY. Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis. J Affect Disord. 2017; 210: 211-221. doi: 10.1016/j.jad.2016.12.048.
  • Oliveira AI, Pinho C, Sarmento B, Dias AC. Neuroprotective activity of Hypericum perforatum and its major components. Front Plant Sci. 2016; 7: 1004. doi: 10.3389/fpls.2016.01004.
  • Russo E, Scicchitano F, Whalley BJ, Mazzitello C, Ciriaco M, Esposito S, et al. Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions. Phytother Res. 2014 May;28(5):643-55. doi: 10.1002/ptr.5050.
  • Schempp CM, Müller KA, Winghofer B, Schöpf E, Simon JC. St. John's wort (Hypericum perforatum L.). A plant with relevance for dermatology. Hautarzt 2002; 53: 316-321.
  • Shelton RC. St Jonn's wort (Hypericum perforatum) in major depression. J Clin Psychiatry 2009; 70: 23-27.
  • Saddiqe Z, Naeem I, Maimoona A. A review of the antibacterial activity of Hypericum perforatum L. J Ethnopharmacol 2010; 131: 511-521.
  • Sarris J. Herbal medicines in the treatment of psychiatric disorders: 10-year updated review. Phytother Res. 2018 Mar 25. doi: 10.1002/ptr.6055
  • Sarris J, Fava M, Schweitzer I, Mischoulon D. St John's wort (Hypericum perforatum) versus sertraline and placebo in major depressive disorder: continuation data from a 26-week RCT. Pharmacopsychiatry. 2012; 45 (7): 275-8. doi: 10.1055/s-0032-1306348.
  • Seifritz E, Hatzinger M, Holsboer-Trachsler E. Efficacy of Hypericum extract WS 5570 compared with paroxetine in patients with a moderate major depressive episode - a subgroup analysis. Int J Psychiatry Clin Pract. 2016; 20 (3): 126-32. doi: 10.1080/13651501.2016.1179765.
  • Swedish Council on Health Technology Assessment. Treatment of depression: a systematic review [Internet]. Stockholm: Swedish Council on Health Technology Assessment (SBU); 2004 Mar.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Verotta L, Appendino G, Bombardelli E, Brun R. In vitro antimalarial activity of hyperforin, a prenylated acylphloroglucinol. A structure-activity study. Bioorg Med Chem Lett 2007; 17: 1544-1548.
  • WHO. ICD-10: International statistical classification of diseases and related health problems. 10ª ed. Geneva: World Heathy Organisation; 2010.

Jengibre

  • Alsherbiny MA, Abd-Elsalam WH, El Badawy SA, Taher E, Fares M, Torres A, et al. Ameliorative and protective effects of ginger and its main constituents against natural, chemical and radiation-induced toxicities: A comprehensive review. Food Chem Toxicol. 2018;123:72-97. doi: 10.1016/j.fct.2018.10.048.
  • Bameshki A, Namaiee MH, Jangjoo A, Dadgarmoghaddam M, Ghalibaf MHE, Ghorbanzadeh A, et al. Effect of oral ginger on prevention of nausea and vomiting after laparoscopic cholecystectomy: a double-blind, randomized, placebo-controlled trial. Electron Physician. 2018; 10 (2): 6354-6362. doi: 10.19082/6354.
  • Banihani SA. Ginger and testosterone. Biomolecules. 2018;8(4). pii: E119. doi: 10.3390/biom8040119.
  • Bossi P, Cortinovis D, Fatigoni S, Cossu Rocca M, Fabi A, Seminara P, et al. A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin. Ann Oncol. 2017; 28 (10): 2547-2551. doi: 10.1093/annonc/mdx315.
  • Bossi P, Cortinovis D, Cossu Rocca M, Roila F, Seminara P, Fabi A, et al. Searching for evidence to support the use of ginger in the prevention of chemotherapy-induced nausea and vomiting. J Altern Complement Med. 2016; 22 (6): 486-8. doi: 10.1089/acm.2015.0315.
  • Dabaghzadeh F, Khalili H, Dashti-Khavidaki S, Abbasian L, Moeinifard A. Ginger for prevention of antiretroviral-induced nausea and vomiting: a randomized clinical trial. Expert Opin Drug Saf. 2014; 13 (7): 859-66. doi: 10.1517/14740338.2014.914170.
  • De Lima RMT, Dos Reis AC, de Menezes APM, Santos JVO, Filho JWGO, Ferreira JRO, et al. Protective and therapeutic potential of ginger (Zingiber officinale) extract and [6]-gingerol in cancer: A comprehensive review. Phytother Res. 2018;32(10):1885-1907. doi: 10.1002/ptr.6134.
  • Ebrahimzadeh Attari V, Malek Mahdavi A, Javadivala Z, Mahluji S, Zununi Vahed S, Ostadrahimi A. A systematic review of the anti-obesity and weight lowering effect of ginger (Zingiber officinale Roscoe) and its mechanisms of action. Phytother Res. 2017 Nov 29. doi: 10.1002/ptr.5986.
  • Edelman MJ, Wang X, Hodgson L, Cheney RT, Baggstrom MQ, Thomas SP, et al. Phase III randomized, placebo-controlled, double-blind trial of celecoxib in addition to standard chemotherapy for advanced non-small-cell lung cancer with cyclooxygenase-2 overexpression: CALGB 30801 (Alliance). J Clin Oncol. 2017; 35 (19): 2184-2192. doi: 10.1200/JCO.2016.71.3743.
  • Effatpanah M, Makhdoomi Arzati R, et al. The effects of ginger on fasting blood sugar, hemoglobin a1c, and lipid profiles in patients with type 2 diabetes. Int J Endocrinol Metab. 2017; 15 (4): e57927. doi: 10.5812/ijem.57927.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Zingiber officinale Roscoe, rhizoma. Ref. Doc. EMA/HMPC/749154/2010. Adopted: 27/9/2012.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Assessment report on Zingiber officinale Roscoe, rhizoma. Ref. Doc. EMA/HMPC/577856/2010. Adopted: 27/3/2012
  • Firouzbakht M, Nikpour M, Jamali B, Omidvar S. Comparison of ginger with vitamin B6 in relieving nausea and vomiting during pregnancy. Ayu. 2014; 35 (3): 289-93. doi: 10.4103/0974-8520.153746.
  • Gaffey A, Slater H, Porritt K, Campbell JM. The effects of curcuminoids on musculoskeletal pain: a systematic review. JBI Database System Rev Implement Rep. 2017;15 (2): b486-516. doi: 10.11124/JBISRIR-2016-003266.
  • Ghasemian M, Owlia S, Owlia MB. Review of anti-inflammatory herbal medicines. Adv Pharmacol Sci. 2016; 2016: 9130979. doi: 10.1155/2016/9130979.
  • Giacosa A, Morazzoni P, Bombardelli E, Riva A, Bianchi Porro G, Rondanelli M. Can nausea and vomiting be treated with ginger extract? Eur Rev Med Pharmacol Sci. 2015; 19 (7): 1291-6.
  • Jafarzadeh A, Nemati M. Therapeutic potentials of ginger for treatment of Multiple sclerosis: A review with emphasis on its immunomodulatory, anti-inflammatory and anti-oxidative properties. J Neuroimmunol. 2018;324:54-75. doi: 10.1016/j.jneuroim.2018.09.003.
  • Khandouzi N, Shidfar F, Rajab A, Rahideh T, Hosseini P, Mir Taheri M. The effects of ginger on fasting blood sugar, hemoglobin a1c, apolipoprotein B, apolipoprotein a-I and malondialdehyde in type 2 diabetic patients. Iran J Pharm Res. 2015; 14 (1): 131-40.
  • Konmun J, Danwilai K, Ngamphaiboon N, Sripanidkulchai B, Sookprasert A, Subongkot S. A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy. Med Oncol. 2017; 34 (4): 69. doi: 10.1007/s12032-017-0931-4.
  • Lantz RC, Chen GJ, Sarihan M, Sólyom AM, Jolad SD, Timmermann BN. The effect of extracts from ginger rhizome on inflammatory mediator production. Phytomedicine 2007; 14:123-128.
  • Li X, Qin Y, Liu W, Zhou XY, Li YN, Wang LY. Efficacy of ginger in ameliorating acute and delayed chemotherapy-induced nausea and vomiting among patients with lung cancer receiving cisplatin-based regimens: a randomized controlled trial. Integr Cancer Ther. 2018 Feb 1:1534735417753541. doi: 10.1177/1534735417753541.
  • Maharlouei N, Tabrizi R, Lankarani KB, Rezaianzadeh A, Akbari M, Kolahdooz F, et al. The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: A systematic review and meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2018: 1-14. doi: 10.1080/10408398.2018.1427044.
  • Mahluji S, Ostadrahimi A, Mobasseri M, Ebrahimzade Attari V, Payahoo L. Anti-inflammatory effects of zingiber officinale in type 2 diabetic patients. Adv Pharm Bull. 2013; 3 (2): 273-6. doi: 10.5681/apb.2013.044.
  • Makhdoomi Arzati M, Mohammadzadeh Honarvar N, Saedisomeolia A, Anvari S,
  • Marx W, McCarthy AL, Ried K, Vitetta L, McKavanagh D, Thomson D, Sali A, Isenring L. Can ginger ameliorate chemotherapy-induced nausea? Protocol of a randomized double blind, placebo-controlled trial. BMC Complement Altern Med. 2014; 14: 134. doi: 10.1186/1472-6882-14-134.
  • Marx W, McCarthy AL, Ried K, McKavanagh D, Vitetta L, Sali A, et al. The effect of a standardized ginger extract on chemotherapy-induced nausea-related quality of life in patients undergoing moderately or highly emetogenic chemotherapy: a double blind, randomized, placebo controlled trial. Nutrients. 2017 Aug; 9 (8). pii: E867. doi: 10.3390/nu9080867.
  • Mozaffari-Khosravi H, Naderi Z, Dehghan A, Nadjarzadeh A, Fallah Huseini H. Effect of ginger supplementation on proinflammatory cytokines in older patients with osteoarthritis: outcomes of a randomized controlled clinical trial. J Nutr Gerontol Geriatr. 2016; 35 (3): 209-18. doi: 10.1080/21551197.2016.1206762.
  • Naderi Z, Mozaffari-Khosravi H, Dehghan A, Nadjarzadeh A, Huseini HF. Effect of ginger powder supplementation on nitric oxide and C-reactive protein in elderly knee osteoarthritis patients: A 12-week double-blind randomized placebo-controlled clinical trial. J Tradit Complement Med. 2015; 6 (3): 199-203. doi: 10.1016/j.jtcme.2014.12.007.
  • Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W. A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial. Nutr J. 2013; 12 (1): 154. doi: 10.1186/1475-2891-12-154.
  • Ozgoli G, Saei Ghare Naz M. Effects of complementary medicine on nausea and vomiting in pregnancy: A systematic review. Int J Prev Med. 2018;9:75. doi: 10.4103/ijpvm.IJPVM_430_16.
  • Pertz HH, Lehmann J, Roth-Ehrang R, Elz S. Effects of ginger constituents on the gastrointestinal tract: role of cholinergic M3 and serotonergic 5-HT3 and 5-HT4 receptors. Planta Med 2011; 77: 973-978.
  • Rayati F, Hajmanouchehri F, Najafi E. Comparison of anti-inflammatory and analgesic effects of Ginger powder and Ibuprofen in postsurgical pain model: A randomized, double-blind, case-control clinical trial. Dent Res J (Isfahan). 2017; 14 (1): 1-7.
  • Shabanian S, Khalili S, Lorigooini Z, Malekpour A, Heidari-Soureshjani S. The effect of vaginal cream containing ginger in users of clotrimazole vaginal cream on vaginal candidiasis. J Adv Pharm Technol Res. 2017; 8 (2): 80-84. doi: 10.4103/japtr.JAPTR_176_16.
  • Sanaati F, Najafi S, Kashaninia Z, Sadeghi M. Effect of Ginger and Chamomile on Nausea and Vomiting Caused by Chemotherapy in Iranian Women with Breast Cancer. Asian Pac J Cancer Prev. 2016; 17 (8): 4125-9.
  • Seidi J, Ebnerasooli S, Shahsawari S, Nzarian S. The influence of oral ginger before operation on nausea and vomiting after cataract surgery under general anesthesia: a double-blind placebo-controlled randomized clinical trial. Electron Physician. 2017; 9 (1): 3508-3514. doi: 10.19082/3508.
  • Shidfar F, Rajab A, Rahideh T, Khandouzi N, Hosseini S, Shidfar S. The effect of ginger (Zingiber officinale) on glycemic markers in patients with type 2 diabetes. J Complement Integr Med. 2015; 12 (2): 165-70. doi: 10.1515/jcim-2014-0021.
  • Stanisiere J, Mousset PY, Lafay S. How safe is ginger rhizome for decreasing nausea and vomiting in women during early pregnancy? Foods. 2018; 7 (4). pii: E50. doi: 10.3390/foods7040050.
  • Thamlikitkul L, Srimuninnimit V, Akewanlop C, Ithimakin S, Techawathanawanna S, Korphaisarn K, et al. Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin-cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study. Support Care Cancer. 2017; 25 (2): 459-464. doi: 10.1007/s00520-016-3423-8.
  • Tsilas CS, de Souza RJ, Mejia SB, Mirrahimi A, Cozma AI, Jayalath VH, et al. Relation of total sugars, fructose and sucrose with incident type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies. CMAJ. 2017; 189 (20): E711-E720. doi: 10.1503/cmaj.160706.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Wang J, Ke W, Bao R, Hu X, Chen F. Beneficial effects of ginger Zingiber officinale Roscoe on obesity and metabolic syndrome: a review. Ann N Y Acad Sci. 2017; 1398 (1): 83-98. doi: 10.1111/nyas.13375.
  • Yekta ZP, Ebrahimi SM, Hosseini M, Nasrabadi AN, Sedighi S, Surmaghi MH, et al. Ginger as a miracle against chemotherapy-induced vomiting. Iran J Nurs Midwifery Res. 2012; 17 (5): 325-9.
  • Yu Y, Zick S, Li X, Zou P, Wright B, Sun D. Examination of the pharmacokinetics of active ingredients of ginger in humans. AAPS J 2011; 13 (3): 417-426.
  • Zhu J, Chen H, Song Z, Wang X, Sun Z. Effects of ginger (Zingiber officinale Roscoe) on type 2 diabetes mellitus and components of the metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials. Evid Based Complement Alternat Med. 2018; 2018: 5692962. doi: 10.1155/2018/5692962.

Laurel

  • Barla A, Topçu G, Öksüz S, Tümen G, Kingston DGI. Identification of cytotoxic sesquiterpenes from Laurus nobilis L. Food Chemistry 2007; 104:1478-1484.
  • Ibtissem Hamrouni Sellami, Wissem Aidi Wannes, Iness Bettaieb, Sarra Berrima, Thouraya Chahed, Brahim Marzouk, et al. Qualitative and quantitative changes in the essential oil of Laurus nobilis L. leaves as affected by different drying methods Food Chemistry 2011; 126: 691-697.

Lavanda

  • Akhondzadeh S, Kashani L, Fotouhi A, Jarvandi S, Mobaseri M, Moin M, et al. Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuropsychopharmacol Biol Psychiatry. 2003; 27 (1): 123-7.
  • Altaei DT. Topical lavender oil for the treatment of recurrent aphthous ulceration. Am J Dent. 2012; 25 (1): 39-43.
  • Ayaz M, Sadiq A, Junaid M, Ullah F, Subhan F, Ahmed J. Neuroprotective and anti-aging potentials of essential oils from aromatic and medicinal plants. Front Aging Neurosci. 2017; 9: 168. doi: 10.3389/fnagi.2017.00168.
  • Ayik C, Özden D. The effects of preoperative aromatherapy massage on anxiety and sleep quality of colorectal surgery patients: A randomized controlled study. Complement Ther Med. 2018;36:93-99. doi: 10.1016/j.ctim.2017.12.002.
  • Barić H, Đorđević V, Cerovečki I, Trkulja V. Complementary and alternative medicine treatments for generalized anxiety disorder: systematic review and meta-analysis of randomized controlled trials. Adv Ther. 2018; 35 (3): 261-288. doi: 10.1007/s12325-018-0680-6.
  • Dwyer AV, Whitten DL, Hawrelak JA. Herbal medicines, other than St. John's Wort, in the treatment of depression: a systematic review. Altern Med Rev. 2011; 16 (1): 40-9.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Lavandula angustifolia Miller, aetheroleum. London: EMA. Doc. Ref.: EMA/HMPC/143181/2010. Adopted: 27 March 2012.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Lavandula angustifolia Miller, flos. London: EMA. Doc. Ref.: EMA/HMPC/734125/2010. Adopted: 27 March 2012.
  • Farshbaf-Khalili A, Kamalifard M, Namadian M. Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women: A triple-blind, randomized, controlled clinical trial. Complement Ther Clin Pract. 2018;31:132-138. doi: 10.1016/j.ctcp.2018.02.004.
  • Han SH, Hur MH, Buckle J, Choi J, Lee MS. Effect of aromatherapy on symptoms of dysmenorrhea in college students: A randomized placebo-controlled clinical trial. J Altern Complement Med. 2006; 12 (6): 535-41.
  • Hassanzadeh M, Kiani F, Bouya S, Zarei M. Comparing the effects of relaxation technique and inhalation aromatherapy on fatigue in patients undergoing hemodialysis. Complement Ther Clin Pract. 2018;31:210-214. doi: 10.1016/j.ctcp.2018.02.019.
  • Howard S, Hughes BM. Expectancies, not aroma, explain impact of lavender aromatherapy on psychophysiological indices of relaxation in young healthy women. Br J Health Psychol. 2008; 13 (Pt 4): 603-17.
  • Kähler C, Derezinski T, Bocian-Sobkowska J, Keckeis A, Zacke G. Spicae aetheroleum in uncomplicated acute bronchitis: a double-blind, randomized clinical trial. Wien Med Wochenschr. 2017 Dec 5. doi: 10.1007/s10354-017-0612-0.
  • Kasper S. An orally administered lavandula oil preparation (Silexan) for anxiety disorder and related conditions: an evidence based review. Int J Psychiatry Clin Pract. 2013;17 (Suppl 1): 15-22. doi: 10.3109/13651501.2013.813555.
  • Kasper S, Anghelescu I, Dienel A. Efficacy of orally administered Silexan in patients with anxiety-related restlessness and disturbed sleep--A randomized, placebo-controlled trial. Eur Neuropsychopharmacol. 2015; 25 (11): 1960-7. doi: 10.1016/j.euroneuro.2015.07.024.
  • Kazemzadeh R, Nikjou R, Rostamnegad M, Norouzi H. Effect of lavender aromatherapy on menopause hot flushing: A crossover randomized clinical trial. J Chin Med Assoc. 2016; 79 (9): 489-92. doi: 10.1016/j.jcma.2016.01.020.
  • Nasiri A, Mahmodi MA. Aromatherapy massage with lavender essential oil and the prevention of disability in ADL in patients with osteoarthritis of the knee: A randomized controlled clinical trial. Complement Ther Clin Pract. 2018;30:116-121. doi: 10.1016/j.ctcp.2017.12.012.
  • Nikfarjam M, Rakhshan R, Ghaderi H. Comparison of Effect of Lavandula officinalis and Venlafaxine in Treating Depression: A Double Blind Clinical Trial. J Clin Diagn Res. 2017; 11 (7): KC01-KC04. doi: 10.7860/JCDR/2017/20657.10233.
  • Ou MC, Hsu TF, Lai AC, Lin YT, Lin CC. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial. J Obstet Gynaecol Res. 2012 May;38(5):817-22. doi: 10.1111/j.1447-0756.2011.01802.x.
  • Tugut N, Demirel G, Baser M, Ata EE, Karakus S. Effects of lavender scent on patients' anxiety and pain levels during gynecological examination. Complement Ther Clin Pract. 2017;28:65-69. doi: 10.1016/j.ctcp.2017.05.006.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Wan-ki Lin P, Chan W, Fung-leung Ng B, Chiu-wa Lam L. Efficacy of aromatheraphy (Lavandula angustifolia) as an intervention for agitated behaviours in Chinese older persons with dementia: a cross-over randomized trial. International Journal of geriatric psychiatry 2007; 22: 405-410.
  • Woelk H, Schläfke S. A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. Phytomedicine. 2010; 17 (2): 94-9. doi: 10.1016/j.phymed.2009.10.006.

Maíz Estigmas

  • Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003; 85: 257-60.
  • Costabile A, Deaville ER, Morales AM, Gibson GR. Prebiotic potential of a maize-based soluble fibre and impact of dose on the human gut microbiota. PLoS One. 2016; 11 (1): e0144457. doi: 10.1371/journal.pone.0144457.
  • De Carvalho FG, Ovídio PP, Padovan GJ, Jordão Junior AA, Marchini JS, et al. Metabolic parameters of postmenopausal women after quinoa or corn flakes intake--a prospective and double-blind study. Int J Food Sci Nutr. 2014; 65 (3): 380-5. doi: 10.3109/09637486.2013.866637.
  • El-Ghorab A, El-Massry KF, Shibamoto T. Chemical composition of the volatile extract and antioxidant activities of the volatile and nonvolatile extracts of Egyptian corn silk (Zea mays L.). J Agric Food Chem 2007; 55: 9124-7.
  • Guo J, Liu T, Han L, Liu Y. The effects of corn silk on glycaemic metabolism. Nutr Metab (Lond) 2009; 6: 47.
  • Holscher HD, Caporaso JG, Hooda S, Brulc JM, Fahey GC Jr, Swanson KS. Fiber supplementation influences phylogenetic structure and functional capacity of the human intestinal microbiome: follow-up of a randomized controlled trial. Am J Clin Nutr. 2015; 101 (1): 55-64. doi: 10.3945/ajcn.114.092064.
  • Kim TI, Choi EJ, Chung CP, Han SB, Ku Y. Antimicorbial effect of Zea Mays L. and Magnoliae cortex extract mixtures on periodontal pathogen and effect on human gingival fibroblast cellular activity. J Korean Acad Periodontol 2002; 32: 249-255.
  • Jakeman SA, Henry CN, Martin BR, McCabe GP, McCabe LD, Jackson GS, et al. Soluble corn fiber increases bone calcium retention in postmenopausal women in a dose-dependent manner: a randomized crossover trial. Am J Clin Nutr. 2016; 104 (3): 837-43. doi: 10.3945/ajcn.116.132761. Erratum in: Am J Clin Nutr. 2017; 105 (3): 772.
  • Maksimović Z, Dobrić S, Kovacević N, Milovanović Z. Diuretic activity of Maydis stigma extract in rats. Pharmazie 2004; 59: 967-71.
  • Maziarz MP, Preisendanz S, Juma S, Imrhan V, Prasad C, Vijayagopal P. Resistant starch lowers postprandial glucose and leptin in overweight adults consuming a moderate-to-high-fat diet: a randomized-controlled trial. Nutr J. 2017; 16 (1): 14. doi: 10.1186/s12937-017-0235-8.
  • O'Connor LE, Campbell WW. A novel fiber composite ingredient incorporated into a beverage and bar blunts postprandial serum glucose and insulin responses: a randomized controlled trial. Nutr Res. 2016 Mar;36(3):253-61. doi: 10.1016/j.nutres.2015.11.015.
  • Timm DA, Thomas W, Boileau TW, Williamson-Hughes PS, Slavin JL. Polydextrose and soluble corn fiber increase five-day fecal wet weight in healthy men and women. J Nutr. 2013; 143 (4): 473-8. doi: 10.3945/jn.112.170118.
  • Velazquez DV, Xavier HS, Batista JE, de Castro-Chaves C. Zea mays L. extracts modify glomerular function and potassium urinary excretion in conscious rats. Phytomedicine 2005; 12: 363-9.
  • Whisner CM, Martin BR, Nakatsu CH, Story JA, MacDonald-Clarke CJ, McCabe LD, et al. Soluble corn fiber increases calcium absorption associated with shifts in the gut microbiome: a randomized dose-response trial in free-living pubertal females. J Nutr. 2016; 146 (7): 1298-306. doi: 10.3945/jn.115.227256.

Malva flor

  • Ameri A, Heydarirad G, Rezaeizadeh H, Choopani R, Ghobadi A, Gachkar L. Evaluation of efficacy of an herbal compound on dry mouth in patients with head and neck cancers: a randomized clinical trial. J Evid Based Complementary Altern Med. 2016; 21 (1): 30-3. doi: 10.1177/2156587215590232.
  • Elsagh M, Fartookzadeh MR, Kamalinejad M, Anushiravani M, Feizi A, Behbahani FA, et al. Efficacy of the Malva sylvestris L. flowers aqueous extract for functional constipation: A placebo-controlled trial. Complement Ther Clin Pract. 2015; 21 (2):105-11. doi: 10.1016/j.ctcp.2015.02.003.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Malva sylvestris L. and/or Malva neglecta Wallr., folium. Amsterdam: EMA. Doc. Ref.: EMA/HMPC/749510/2016. Adopted: 20/11/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Malva sylvestris L. and/or Malva neglecta Wallr., flos. London: EMA. Doc. Ref.: EMA/HMPC/749511/2016. Adopted: 20/11/2018.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Assessment report on Malva sylvestris L. and/or Malva neglecta Wallr., folium and Malva sylvestris L., flos. Amsterdam: EMA. Doc. Ref.: EMA/HMPC/749518//2016. Adopted: 20/11/2018.
  • European Medicines Agency (EMA )- Committee on Herbal Medicinal Products (HMPC). List of references supporting the assessment of Malva sylvestris L. and/or Malva neglecta Wallr.,folium and Malva sylvestris L., flos. Amsterdam: EMA. Doc. Ref.: EMA/HMPC/749540/2016. Adopted: 20/11/2018.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Mallow Flower (Malvae flos). Exeter: ESCOP, 2016.
  • Gasparetto JC, Martins CA, Hayashi SS, Otuky MF, Pontarolo R. Ethnobotanical and scientific aspects of Malva sylvestris L.: a millennial herbal medicine. J Pharm Pharmacol. 2012; 64 (2): 172-89. doi: 10.1111/j.2042-7158.2011.01383.x.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.

Manzanilla Amarga

  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Chamaemelum nobile (L.) All., flos. London: EMA. Doc. Ref.: EMA/HMPC/560734/2010. Adopted: 22 November 2011.
  • Johnson W Jr, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, et al. Safety assessment of Anthemis nobilis-derived ingredients as used in cosmetics. Int J Toxicol. 2017; 36 (suppl 1): 57S-66S. doi: 10.1177/1091581817705620.
  • Kazemian H, Ghafourian S, Sadeghifard N, Houshmandfar R, Badakhsh B, Taji A, et al. In vivo antibacterial and wound healing activities of roman chamomile (Chamaemelum nobile). Infect Disord Drug Targets. 2018;18(1):41-45. doi: 10.2174/1871526516666161230123133.
  • Lopez Jornet P, Aznar-Cayuela C. Efficacy of topical chamomile management vs. placebo in patients with oral lichen planus: a randomized double-blind study. J Eur Acad Dermatol Venereol. 2016; 30 (10): 1783-1786. doi: 10.1111/jdv.13770.
  • Sõukand R, Quave CL, Pieroni A, Pardo-de-Santayana M, Tardío J, Kalle R, et al. Plants used for making recreational tea in Europe: a review based on specific research sites. J Ethnobiol Ethnomed. 2013; 9 (1): 58. doi: 10.1186/1746-4269-9-58.
  • Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the past with bright future. Mol Med Rep. 2010; 3 (6): 895-901.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.

Manzanilla dulce

  • Amsterdam JD, Shults J, Soeller I, Mao JJ, Rockwell K, Newberg AB. Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study. Altern Ther Health Med 2012; 18 (5): 44-9.
  • Amsterdam JD, Li Y, Soeller I, Rockwell K, Mao JJ, Shults J. A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder. J Clin Psychopharmacol 2009; 29 (4): 378-82. doi: 10.1097/JCP.0b013e3181ac935c.
  • Anheyer D, Frawley J, Koch AK, Lauche R, Langhorst J, Dobos G, et al. Herbal Medicines for gastrointestinal disorders in children and adolescents: a systematic review. Pediatrics. 2017; 139 (6). pii: e20170062. doi: 10.1542/peds.2017-0062.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Matricaria recutita L., aetheroleum. London: EMA. Doc. Ref.: EMA/HMPC/278814/2010. Adopted: 7 July 2015.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Matricaria recutita L., flos. London: EMA. Doc. Ref.: EMA/HMPC/55843/2011. Adopted: 7 July 2015.
  • Gomes VTS, Nonato Silva Gomes R, Gomes MS, Joaquim WM, Lago EC, Nicolau RA. Effects of Matricaria Recutita (L.) in the treatment of oral mucositis. ScientificWorldJournal. 2018;2018:4392184. doi: 10.1155/2018/4392184.
  • Goes P, Dutra CS, Lisboa MR, Gondim DV, Leitão R, Brito GA, Rego RO. Clinical efficacy of a 1% Matricaria chamomile L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances. J Oral Sci. 2016; 58 (4): 569-574. doi: 10.2334/josnusd.16-0280.
  • Hashempur MH, Ghasemi MS, Daneshfard B, Ghoreishi PS, Lari ZN, Homayouni K, et al. Efficacy of topical chamomile oil for mild and moderate carpal tunnel syndrome: A randomized double-blind placebo-controlled clinical trial. Complement Ther Clin Pract. 2017; 26: 61-67. doi: 10.1016/j.ctcp.2016.11.010.
  • Madisch A, Holtmann G, Mayr G, Vinson B, Hotz J. Treatment of functional dyspepsia with a herbal preparation. A double-blind, randomized, placebo-controlled, multicenter trial. Digestion 2004; 69 (1): 45-52.
  • Miraj S, Alesaeidi S. A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile). Electron Physician. 2016; 8 (9): 3024-3031.
  • Mao JJ, Li QS, Soeller I, Rockwell K, Xie SX, Amsterdam JD. Long-term chamomile therapy of generalized anxiety disorder: a study protocol for a randomized, double-blind, placebo- controlled trial. J Clin Trials. 2014; 4 (5). pii: 188. doi: 10.4172/2167-0870.1000188.
  • Ross SM. Generalized anxiety disorder (GAD): efficacy of standardized Matricaria recutita (German chamomile) extract in the treatment of generalized anxiety disorder. Holist Nurs Pract 2013; 27 (6): 366-8. doi: 10.1097/HNP.0b013e3182a8eb62.
  • Saghafi N, Rhkhshandeh H, Pourmoghadam N, Pourali L, Ghazanfarpour M, Behrooznia A, et al. Effectiveness of Matricaria chamomilla (chamomile) extract on pain control of cyclic mastalgia: a double-blind randomised controlled trial. J Obstet Gynaecol. 2018; 38 (1): 81-84. doi: 10.1080/01443615.2017.1322045.
  • Sharifi F, Simbar M, Mojab F, Majd HA. Comparison of the effects of Matricaria chamomila (Chamomile) extract and mefenamic acid on the intensity of premenstrual syndrome. Complement Ther Clin Pract 2014; 20 (1): 81-8. doi: 10.1016/j.ctcp.2013.09.002.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia 2014; 14 (1): 5-36.
  • Zargaran A, Borhani-Haghighi A, Salehi-Marzijarani M, Faridi P, Daneshamouz S, Azadi A, et al. Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura: a randomized, double-blind, placebo-controlled, crossover study. Neurol Sci. 2018;39(8):1345-1353. doi: 10.1007/s10072-018-3415-1.
  • Zick SM, Wright BD, Sen A, Arnedt JT. Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: a randomized placebo-controlled pilot study. BMC Complement Altern Med 2011; 11: 78. doi: 10.1186/1472-6882-11-78.

Mejorana

  • Bina F, Rahimi R. Sweet Marjoram: A Review of ethnopharmacology, phytochemistry, and biological activities. J Evid Based Complementary Altern Med. 2017; 22 (1): 175-185.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final European Union herbal monograph on Origanum majorana L., herba. London: EMA. Doc. Ref.: EMA/HMPC/166517/2015. Adopted: 20 September 2016.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final assessment report on Origanum majorana L., herba . London: EMA. Doc. Ref.: EMA/HMPC/63479/2015. Adopted: 20 September 2016.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final list of references supporting the assessment of Origanum majorana L., herba. London: EMA. Doc. Ref.: EMA/HMPC/63480/2015. Adopted: 20 September 2016.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Herbal medicine: summary for the public. Marjoram (Origanum majorana L., herba). London: EMA. Doc. Ref.: EMA/653011/2016. Adopted: 22 November 2016.
  • Leyva-López N, Gutiérrez-Grijalva EP, Vazquez-Olivo G, Heredia JB. Essential oils of oregano: biological activity beyond their antimicrobial properties. Molecules. 2017; 22 (6). pii: E989. doi: 10.3390/molecules22060989.
  • Pérez-Recalde M, Ruiz Arias IE, Hermida ÉB. Could essential oils enhance biopolymers performance for wound healing? A systematic review. Phytomedicine. 2018; 38: 57-65. doi: 10.1016/j.phymed.2017.09.024.
  • Sõukand R, Quave CL, Pieroni A, Pardo-de-Santayana M, Tardío J, Kalle R, et al. Plants used for making recreational tea in Europe: a review based on specific research sites. J Ethnobiol Ethnomed. 2013; 9 (1): 58. doi: 10.1186/1746-4269-9-58.

Melisa

  • 378-84. doi: 10.1016/j.jep.2015.02.007.
  • Ballard CG, O'Brien JT, Reichelt K, Perry EK. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry 2002; 63: 553-558.
  • Buchbauer G, Jirovetz L, Jäger W, Plank C, Dietrich H. Fragrance compounds and essential oils with sedative effects upon inhalation. J Pharm Sci 1993; 82: 660-664.
  • Burns A, Perry E, Holmes C, Francis P, Morris J, Howes MJ, et al. A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitation in Alzheimer's disease. Dement Geriatr Cogn Disord. 2011; 31(2):158-64. doi: 10.1159/000324438.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Melissa officinalis L., folium. London: EMA. Doc. Ref.: EMEA/HMPC/196745/2012. Adopted: 14/5/2013.
  • Jandaghi P, Noroozi M, Ardalani H, Alipour M. Lemon balm: A promising herbal therapy for patients with borderline hyperlipidemia-A randomized double-blind placebo-controlled clinical trial. Complement Ther Med. 2016; 26: 136-40. doi: 10.1016/j.ctim.2016.03.012.
  • Kargozar R, Azizi H, Salari R. A review of effective herbal medicines in controlling menopausal symptoms. Electron Physician. 2017; 9 (11):5826-5833. doi: 10.19082/5826.
  • Kennedy DO, Little W, Haskell CF, Scholey AB. Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress. Phytother Res. 2006;20 (2): 96-102.
  • Kennedy DO, Wake G, Savelev S, Tildesley NT, Perry EK, Wesnes KA, Scholey AB. Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties. Neuropsychopharmacology. 2003; 28 (10): 1871-81.
  • Koytchev R, Alken RG, Dundarov S. Balm mint extract (Lo-701) for topical treatment of recurring herpes labialis. Phytomedicine. 1999; 6 (4): 225-30.
  • Maleki-Saghooni N, Karimi FZ, Behboodi Moghadam Z, Mirzaii Najmabadi K. The effectiveness and safety of Iranian herbal medicines for treatment of premenstrual syndrome: A systematic review. Avicenna J Phytomed. 2018; 8 (2): 96-113.
  • Mazzanti G, Battinelli L, Pompeo C, Serrilli AM, Rossi R, Sauzullo I, et al. Inhibitory activity of Melissa officinalis L. extract on Herpes simplex virus type 2 replication. Nat Prod Res 2008; 22 (16): 1433-40. doi: 10.1080/14786410802075939.
  • Moradi MT, Rafieian-Kopaei M, Karimi A. A review study on the effect of Iranian herbal medicines against in vitro replication of herpes simplex virus. Avicenna J Phytomed. 2016; 6 (5): 506-515.
  • Muller SF, Klement S. A combination of valerian and lemonbalm is effective in the treatment of restlessness and dyssomnia in children. Phytomedicine 2006; 13: 383-391.
  • Noguchi-Shinohara M, Ono K, Hamaguchi T, Iwasa K, Nagai T, Kobayashi S, Nakamura H, Yamada M. Pharmacokinetics, safety and tolerability of Melissa officinalis extract which contained rosmarinic acid in healthy individuals: a randomized controlled trial. PLoS One. 2015 May 15;10(5):e0126422. doi: 10.1371/journal.pone.0126422.
  • Scholey A, Gibbs A, Neale C, Perry N, Ossoukhova A, Bilog V, Kras M, Scholz C, Sass M, Buchwald-Werner S. Anti-stress effects of lemon balm-containing foods. Nutrients. 2014; 6 (11): 4805-21. doi: 10.3390/nu6114805.
  • Shakeri A, Sahebkar A, Javadi B. Melissa officinalis L. - A review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2016; 188: 204-28. doi: 10.1016/j.jep.2016.05.010.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Wightman EL. Potential benefits of phytochemicals against Alzheimer's disease. Proc Nutr Soc. 2017; 76 (2): 106-112. doi: 10.1017/S0029665116002962.

Menta Piperita

  • Ayaz M, Sadiq A, Junaid M, Ullah F, Subhan F, Ahmed J. Neuroprotective and anti-aging potentials of essential oils from aromatic and medicinal plants. Front Aging Neurosci. 2017; 9: 168. doi: 10.3389/fnagi.2017.00168.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Mentha x piperita L. aetheroleum. London: EMEA. Doc. Ref. EMEA/HMPC/349466/2006. Adopted: 31/10/2007.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Mentha x piperita L., folium. Draft. London: EMA. Doc Ref: EMA/HMPC/572705/2014. Adopted: 23/2/2017.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Menthae piperitae folium (Peppermint leaf). Exeter: ESCOP; 2019.
  • Grigoleit HG, Grigoleit P. Pharmacology and preclinical pharmacokinetics of peppermint oil. Phytomedicine. 2005; 12 (8): 612-6.
  • Grigoleit HG, Grigoleit P. Gastrointestinal clinical pharmacology of peppermint oil. Phytomedicine. 2005; 12 (8):607-11.
  • Grigoleit HG, Grigoleit P. Peppermint oil in irritable bowel syndrome. Phytomedicine. 2005; 12 (8): 601-6.
  • Keifer D, Ulbricht C, Abrams TR, Basch E, Giese N, Giles M, et al. Peppermint (Mentha piperita): an evidence-based systematic review by the Natural Standard Research Collaboration. J Herb Pharmacother. 2007; 7 (2): 91-143.
  • McKay DL, Blumberg JB, A review of the bioactivity and potential health benefits of Peppermint tea (Mentha piperita L.). Phytother Res 2006; 20(8): 619-633.
  • Pasha H, Behmanesh F, Mohsenzadeh F, Hajahmadi M, Moghadamnia AA. Study of the effect of mint oil on nausea and vomiting during pregnancy. Iran Red Crescent Med J. 2012; 14 (11): 727-30. doi: 10.5812/ircmj.3477.
  • Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am J Gastroenterol. 1998; 93 (7): 1131-5.
  • Riachi LG, De Maria CA. Peppermint antioxidants revisited. Food Chem. 2015; 176: 72-81. doi: 10.1016/j.foodchem.2014.12.028.
  • Tayarani-Najaran Z, Talasaz-Firoozi E, Nasiri R, Jalali N, Hassanzadeh M. Antiemetic activity of volatile oil from Mentha spicata and Mentha × piperita in chemotherapy-induced nausea and vomiting. Ecancermedicalscience. 2013; 7: 290. doi: 10.3332/ecancer.2013.290.
  • Thompson Coon J, Ernst E. Systematic review: herbal medicinal products for non-ulcer dyspepsia. Aliment Pharmacol Ther. 2002; 16 (10): 1689-99.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.

Mezcla Andalusí

  • La propia de sus componentes.

Olivo hojas

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  • Ali-Shtayeh MS, Jamous RM, Jamous RM. Complementary and alternative medicine use amongst Palestinian diabetic patients. Complement Ther Clin Pract 2012;18 (1): 16-21. doi: 10.1016/j.ctcp.2011.09.001.
  • Barbaro B, Toietta G, Maggio R, Arciello M, Tarocchi M, Galli A, Balsano C. Effects of the olive-derived polyphenol oleuropein on human health. Int J Mol Sci. 2014; 15 (10): 18508-24. doi: 10.3390/ijms151018508.
  • Briante R, La Cara F, Febbraio F, Patumi M, Nucci R. Bioactive derivatives from oleuropein by a biotransformation on Olea europaea leaf extracts. J Biotechnol 2002 14; 93 (2): 109-19.
  • Briante R, Patumi M, Terenziani S, Bismuto E, Febbraio F, Nucci R. Olea europaea L. leaf extract and derivatives: antioxidant properties. J Agric Food Chem 2002; 50 (17): 4934-40.
  • Casamenti F, Stefani M. Olive polyphenols: new promising agents to combat aging-associated neurodegeneration. Expert Rev Neurother. 2017; 17 (4): 345-358. doi: 0.1080/14737175.2017.1245617.
  • Cherif S, Rahal N, Haouala M, Hizaoui B, Dargouth F, Gueddiche M, et al. Flavonoids from leaves of Olea europaea L. cultivars. Ann Pharm Fr 1998; 56 (6):268-73.
  • Chin KY, Ima-Nirwana S. Olives and bone: a green osteoporosis prevention option. Int J Environ Res Public Health. 2016 Jul 26;13(8). pii: E755. doi: 10.3390/ijerph13080755.
  • De Bock M, Derraik JG, Brennan CM, Biggs JB, Morgan PE, Hodgkinson SC, et al. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial. PLoS One. 2013;8(3):e57622. doi: 10.1371/journal.pone.0057622.
  • De la Fuente P, Chamorro P, Moreno M, Poza MA. Propiedades antioxidantes del hidroxitirosol procedente de la hoja de olivo. Revista de Fitoterapia 2004; 4 (2): 139-147.
  • Efentakis P, Iliodromitis EK, Mikros E, Papachristodoulou A, Dagres N, Skaltsounis AL, et al. Effects of the olive tree leaf constituents on myocardial oxidative damage and atherosclerosis. Planta Med. 2015; 81 (8): 648-54. doi: 10.1055/s-0035-1546017.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Olea europaea L., folium. London: EMA. Doc. Ref.: EMA/HMPC/430507/2009. Adopted: 22 November 2011.
  • Fukumitsu S, Villareal MO, Aida K, Hino A, Hori N, Isoda H, Naito Y. Maslinic acid in olive fruit alleviates mild knee joint pain and improves quality of life by promoting weight loss in the elderly. J Clin Biochem Nutr. 2016; 59 (3): 220-225.
  • Ghasemian M, Owlia S, Owlia MB. Review of anti-inflammatory herbal medicines. Adv Pharmacol Sci. 2016; 2016: 9130979. doi: 10.1155/2016/9130979.
  • Gorzynik-Debicka M, Przychodzen P, Cappello F, Kuban-Jankowska A, Marino Gammazza A, et al. Potential health benefits of olive oil and plant polyphenols. Int J Mol Sci. 2018; 19 (3). pii: E686. doi: 10.3390/ijms19030686.
  • Gouvinhas I, Machado N, Sobreira C, Domínguez-Perles R, Gomes S, Rosa E, Barros AIRNA. Critical review on the significance of olive phytochemicals in plant physiology and human health. Molecules. 2017; 22 (11). pii: E1986. doi: 10.3390/molecules22111986.
  • Hansen K, Adsersen A, Christensen SB, Jensen SR, Nyman U, Smitt UW. Isolation of an angiotensin converting enzime (ACE) inhibitor from Olea europaea and Olea lancea. Phytomedicine 1996; 2: 319-325.
  • Hashmi MA, Khan A, Hanif M, Farooq U, Perveen S. Traditional uses, phytochemistry, and pharmacology of Olea europaea (olive). Evid Based Complement Alternat Med. 2015; 2015: 541591. doi: 10.1155/2015/541591.
  • Imran M, Nadeem M, Gilani SA, Khan S, Sajid MW, Amir RM. Antitumor perspectives of oleuropein and its metabolite hydroxytyrosol: recent updates. J Food Sci. 2018;83(7):1781-1791. doi: 10.1111/1750-3841.14198.
  • Khayyal MT et al. Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats. Arzneimittelforschung 2002; 52 (11): 797-802.
  • Larussa T, Oliverio M, Suraci E, Greco M, Placida R, Gervasi S, et al. Oleuropein decreases cyclooxygenase-2 and interleukin-17 expression and attenuates inflammatory damage in colonic samples from ulcerative colitis patients. Nutrients. 2017; 9 (4). pii: E391. doi: 10.3390/nu9040391.
  • Lockyer S, Corona G, Yaqoob P, Spencer JP, Rowland I. Secoiridoids delivered as olive leaf extract induce acute improvements in human vascular function and reduction of an inflammatory cytokine: a randomised, double-blind, placebo-controlled, cross-over trial. Br J Nutr. 2015; 114 (1): 75-83. doi: 10.1017/S0007114515001269.
  • Lockyer S, Rowland I, Spencer JPE, Yaqoob P, Stonehouse W. Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial. Eur J Nutr. 2017; 56 (4): 1421-1432. doi: 10.1007/s00394-016-1188-y.
  • Luo HQ, Shen J, Chen CP, Ma X, Lin C, Ouyang Q, et al. Lipid-lowering effects of oleanolic acid in hyperlipidemic patients. Chin J Nat Med. 2018;16(5):339-346. doi: 10.1016/S1875-5364(18)30065-7.
  • Pantano D, Luccarini I, Nardiello P, Servili M, Stefani M, Casamenti F. Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology. Br J Clin Pharmacol. 2017; 83 (1): 54-62. doi: 10.1111/bcp.12993.
  • Perona JS, Cañizares J, Montero E, Sánchez-Domínguez JM, Ruiz-Gutierrez V. Plasma lipid modifications in elderly people after administration of two virgin olive oils of the same variety (Olea europaea var. hojiblanca) with different triacylglycerol composition. Br J Nutr 2003;89 (6): 819-26.
  • Saibandith B, Spencer JPE, Rowland IR, Commane DM. Olive polyphenols and the metabolic syndrome. Molecules. 2017; 22 (7). pii: E1082. doi: 10.3390/molecules22071082.
  • Schwingshackl L, Lampousi AM, Portillo MP, Romaguera D, Hoffmann G, Boeing H. Olive oil in the prevention and management of type 2 diabetes mellitus: a systematic review and meta-analysis of cohort studies and intervention trials. Nutr Diabetes. 2017; 7 (4): e262. doi: 10.1038/nutd.2017.12.
  • Susalit E, Agus N, Effendi I, Tjandrawinata RR, Nofiarny D, Perrinjaquet-Moccetti T, et al. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with Captopril. Phytomedicine 2011; 18 (4): 251-8. doi: 10.1016/j.phymed.2010.08.016.
  • Takeda R, Koike T, Taniguchi I, Tanaka K. Double-blind placebo-controlled trial of hydroxytyrosol of Olea europaea on pain in gonarthrosis. Phytomedicine. 2013; 20 (10): 861-4. doi: 10.1016/j.phymed.2013.03.021.
  • Tshongo Muhindo C, Ahn SA, Rousseau MF, Dierckxsens Y, Hermans MP. Efficacy and safety of a combination of red yeast rice and olive extract in hypercholesterolemic patients with and without statin-associated myalgia. Complement Ther Med. 2017; 35: 140-144. doi: 10.1016/j.ctim.2017.
  • Verhoeven V, Van der Auwera A, Van Gaal L, Remmen R, Apers S, Stalpaert M, Wens J, Hermans N. Can red yeast rice and olive extract improve lipid profile and cardiovascular risk in metabolic syndrome?: A double blind, placebo controlled randomized trial. BMC Complement Altern Med. 2015; 15: 52. doi: 10.1186/s12906-015-0576-9.
  • Vilaplana-Pérez C, Auñón D, García-Flores LA, Gil-Izquierdo A. Hydroxytyrosol and potential uses in cardiovascular diseases, cancer, and AIDS. Front Nutr. 2014; 1: 18. doi: 10.3389/fnut.2014.00018.
  • Wainstein J, Ganz T, Boaz M, Bar Dayan Y, Dolev E, Kerem Z, et al. Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats. J Med Food 2012; 15 (7): 605-10. doi: 10.1089/jmf.2011.0243.
  • Wong RH, Garg ML, Wood LG, Howe PR. Antihypertensive potential of combined extracts of olive leaf, green coffee bean and beetroot: a randomized, double-blind, placebo-controlled crossover trial. Nutrients. 2014; 6 (11): 4881-94. doi: 10.3390/nu6114881.

Orégano

  • Nirumand MC, Hajialyani M, Rahimi R, Farzaei MH, Zingue S, Nabavi SM, et al. Dietary plants for the prevention and management of kidney stones: preclinical and clinical evidence and molecular mechanisms. Int J Mol Sci. 2018; 19 (3). pii: E765. doi: 10.3390/ijms19030765.
  • Ozdemir B, Ekbul A, Topal NB, Sarandöl E, Sağ S, Başer KH, et al. Effects of Origanum onites on endothelial function and serum biochemical markers in hyperlipidaemic patients. J Int Med Res. 2008; 36 (6): 1326-34.
  • Sõukand R, Quave CL, Pieroni A, Pardo-de-Santayana M, Tardío J, Kalle R, et al. Plants used for making recreational tea in Europe: a review based on specific research sites. J Ethnobiol Ethnomed. 2013; 9 (1): 58. doi: 10.1186/1746-4269-9-58.
  • Sharifi-Rad M, Varoni EM, Iriti M, Martorell M, Setzer WN, Del Mar Contreras M, et al. Carvacrol and human health: a comprehensive review. Phytother Res. 2018;32(9):1675-1687. doi: 10.1002/ptr.6103.
  • Tepe B, Cakir A, Sihoglu Tepe A. Medicinal Uses, Phytochemistry, and pharmacology of Origanum onites (L.): a review. Chem Biodivers. 2016; 13 (5): 504-20. doi: 10.1002/cbdv.201500069. Review. PubMed PMID: 27062715.

Ortiga Verde

  • Allkanjari O, Vitalone A. What do we know about phytotherapy of benign prostatic hyperplasia? Life Sci. 2015; 126: 42-56. doi: 10.1016/j.lfs.2015.01.023.
  • Cai T, Mazzoli S, Bechi A, Addonisio P, Mondaini N, Pagliai RC, Bartoletti R. Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study. Int J Antimicrob Agents 2009; 33 (6): 549-53. doi: 10.1016/j.ijantimicag.2008.11.012.
  • Chrubasik JE, Roufogalis BD, Wagner H, Chrubasik S. A comprehensive review on the stinging nettle effect and efficacy profiles. Part II: urticae radix. Phytomedicine 2007; 14 (7-8): 568-79.
  • Engelmann U, Walther C, Bondarenko B, Funk P, Schläfke S. Efficacy and safety of a combination of sabal and urtica extract in lower urinary tract symptoms. A randomized, double-blind study versus tamsulosin. Arzneimittelforschung 2006; 56 (3): 222-9.
  • EMA-HMPC. Community herbal monograph on Urtica dioica L.; Urtica urens L., folium. London: EMA. Doc. Ref.: EMA/HMPC/508015/2007. Adopted: 14-1-2010.
  • European Medicines Agency (EMA)-Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Urtica dioica L. and Urtica urens L., herba. London: EMA. Doc. Ref.: EMEA/HMPC/170261/2006. Adopted: 4-9-2008.
  • European Medicines Agency (EMA)-Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Urtica dioica L., Urtica urens L., their hybrids or their mixtures, radix. London: EMA. Doc. Ref.: EMA/HMPC/461160/2008. Adopted: 24-9-2012.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Species diureticae. London: EMA. Doc. Ref.: EMA/HMPC/224755/2016. Adopted: 21/7/2016.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Urticae folium/herba (Nettle leaf/herb). Exeter: ESCOP; 2018.
  • European Scientific Cooperative On Phytotherapy. ESCOP monographs The Scientific Foundation for Herbal Medicinal Products. Online series. Urticae radix (Nettle root). Exeter: ESCOP; 2015.
  • Ghasemian M, Owlia S, Owlia MB. Review of anti-inflammatory herbal medicines. Adv Pharmacol Sci. 2016; 2016: 9130979. doi: 10.1155/2016/9130979.
  • Ghorbanibirgani A, Khalili A, Zamani L. The efficacy of stinging nettle (urtica dioica) in patients with benign prostatic hyperplasia: a randomized double-blind study in 100 patients. Iran Red Crescent Med J. 2013; 15 (1): 9-10. doi: 10.5812/ircmj.2386.
  • Kianbakht S, Khalighi-Sigaroodi F, Dabaghian FH. Improved glycemic control in patients with advanced type 2 diabetes mellitus taking Urtica dioica leaf extract: a randomized double-blind placebo-controlled clinical trial. Clin Lab. 2013; 59 (9-10): 1071-6.
  • Koch E. Extracts from fruits of saw palmetto (Sabal serrulata) and roots of stinging nettle (Urtica dioica): viable alternatives in the medical treatment of benign prostatic hyperplasia and associated lower urinary tracts symptoms. Planta Med 2001; 67 (6): 489-500.
  • Kregiel D, Pawlikowska E, Antolak H. Urtica spp.: ordinary plants with extraordinary properties. Molecules. 2018;23(7). pii: E1664. doi: 10.3390/molecules23071664.
  • Lopatkin N, Sivkov A, Schläfke S, Funk P, Medvedev A, Engelmann U. Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms--long-term follow-up of a placebo-controlled, double-blind, multicenter trial. Int Urol Nephrol 2007; 39 (4): 1137-46.
  • Lopatkin N, Sivkov A, Walther C, Schläfke S, Medvedev A, Avdeichuk J, et al. Long-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms--a placebo-controlled, double-blind, multicenter trial. World J Urol 2005; 23 (2): 139-46.
  • Melo EA, Bertero EB, Rios LA, Mattos D Jr. Evaluating the efficiency of a combination of Pygeum africanum and stinging nettle (Urtica dioica) extracts in treating benign prostatic hyperplasia (BPH): double-blind, randomized, placebo controlled trial. Int Braz J Urol 2002; 28 (5): 418-25.
  • Namazi N, Esfanjani AT, Heshmati J, Bahrami A. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial. Pak J Biol Sci 2011; 14 (15): 775-9.
  • Namazi N, Tarighat A, Bahrami A. The effect of hydro alcoholic nettle (Urtica dioica) extract on oxidative stress in patients with type 2 diabetes: a randomized double-blind clinical trial. Pak J Biol Sci. 2012; 15 (2): 98-102.
  • Nirumand MC, Hajialyani M, Rahimi R, Farzaei MH, Zingue S, Nabavi SM, et al. dietary plants for the prevention and management of kidney stones: preclinical and clinical evidence and molecular mechanisms. Int J Mol Sci. 2018; 19 (3). pii: E765. doi: 10.3390/ijms19030765.
  • Oelke M, Berges R, Schläfke S, Burkart M. Fixed-dose combination PRO 160/120 of sabal and urtica extracts improves nocturia in men with LUTS suggestive of BPH: re-evaluation of four controlled clinical studies. World J Urol. 2014; 32 (5): 1149-54. doi: 10.1007/s00345-014-1338-x.
  • Pagano E, Laudato M, Griffo M, Capasso R. Phytotherapy of benign prostatic hyperplasia. A minireview. Phytother Res. 2014; 28 (7): 949-55.
  • Randall C, Dickens A, White A, Sanders H, Fox M, Campbell J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther Med 2008; 16 (2): 66-72. doi: 10.1016/j.ctim.2007.01.012.
  • Randall C, Randall H, Dobbs F, Hutton C, Sanders H. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000; 93 (6): 305-9.
  • Safarinejad MR. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. J Herb Pharmacother 2005; 5 (4): 1-11.
  • Sökeland J. Combined sabal and urtica extract compared with finasteride in men with benign prostatic hyperplasia: analysis of prostate volume and therapeutic outcome. BJU Int 2000; 86 (4): 439-42.
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  • Wegener T. Utilidad del jugo de sumidad de ortiga en el tratamiento de afecciones urológicas y reumatológicas. Revista de Fitoterapia 2011; 11 (1): 23-31.
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Pasiflora Encarnata

  • Akhondzadeh S, Kashani L, Mobaseri M, Hosseini SH, Nikzad S, Khani M. Passionflower in the treatment of opiates withdrawal: a double-blind randomized controlled trial. Journal of Clinical Pharmacy and Therapeutics 2001; 26 (5): 369-73.
  • Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. Journal of Clinical Pharmacy and Therapeutics 2001; 26: 363-367.
  • Aoyagi N, Kimura R, Murata T. Studies on passiflora incarnata dry extract. I. Isolation of maltol and pharmacological action of maltol and ethyl maltol. Chemical & Pharmaceutical Bulletin 1974; 22 (5): 1008-1013.
  • Appel K, Rose T, Fiebich B, Kammler T, Hoffmann C, Weiss G. Modulation of the γ-aminobutyric acid (GABA) system by Passiflora incarnata L. Phytother Res 2011; 25 (6): 838-843.
  • Aslanargun P, Cuvas O, Dikmen B, Aslan E, Yuksel MU. Passiflora incarnata Linneaus as an anxiolytic before spinal anesthesia. J Anesth. 2012; 26 (1): 39-44. doi: 10.1007/s00540-011-1265-6.
  • Dantas LP, de Oliveira-Ribeiro A, de Almeida-Souza LM, Groppo FC. Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction. Med Oral Patol Oral Cir Bucal. 2017; 22 (1): e95-e101. Dhawan K, Dhawan S, Sharma A. Passiflora: a review update. Journal of Ethnopharmacology 2004; 94: 1-23.
  • Ebrahimie M, Bahmani M, Shirzad H, Rafieian-Kopaei M, Saki K. A Review study on the effect of Iranian herbal medicines on opioid withdrawal syndrome. J Evid Based Complementary Altern Med. 2015; 20 (4): 302-9. doi: 10.1177/2156587215577896.
  • EMA-HMPC. Community herbal monograph on Passiflora incarnata L., herba. London: EMA. Doc. Ref: EMA/HMPC/669740/2013. Adopted 25 March 2014.
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  • Kargozar R, Azizi H, Salari R. A review of effective herbal medicines in controlling menopausal symptoms. Electron Physician. 2017; 9 (11): 5826-5833. doi: 10.19082/5826.
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  • Li QM, van den Heuvel H, Delorenzo O, Corthout J, Pieters LA, Vlietinck AJ, et al. Mass spectral characterization of C-glycosidic flavonoids isolated from a medicinal plant (Passiflora incarnata). Journal of Chromatography 1991; 562 (1-2): 435-446.
  • Passiflora for anxiety disorder. Cochrane Database Syst Rev. 2007; (1): CD004518.
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  • Miyasaka LS, Atallah AN, Soares BGO. Passiflora for anxiety disorder. Cochrane Database of Systematic Reviews 2007, Issue 1. Art. No.: CD004518. DOI: 10.1002/14651858.CD004518.pub2.
  • Movafegh A, Alizadeh R, Hajimohamadi F, Esfehani F, Nejatfar M. Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study. Anesthesia and Analgesia 2008; 106 (6): 1728-32.
  • Ngan A, Conduit R. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011; 25 (8): 1153-9. doi: 10.1002/ptr.3400.
  • Sarris J. Herbal medicines in the treatment of psychiatric disorders: 10-year updated review. Phytother Res. 2018 Mar 25. doi: 10.1002/ptr.6055.
  • Sarris J, Panossian A, Schweitzer I, Stough C, Scholey A. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence. Eur Neuropsychopharmacol 2011;21 (12): 841-60. doi: 10.1016/j.euroneuro.2011.04.002.
  • Soulimani R, Younos C, Jarmouni S, Bousta D, Misslin R, MortierF. Behavioural effects of Passiflora incarnata L. and its indole alkaloid and flavonoid derivatives and maltol in the mouse. Journal of Ethnopharmacology 1997; 57: 11-20.
  • Speroni E, Minghetti A. Neuropharmacological activity of extracts from Passiflora incarnata. Planta Medica 1988; 54 (6): 488-491.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.

Perejil

  • Hasta la fecha no se han encontrado referencias bibliográficas. Se compartirán si se publican.

Pimentón

  • Anónimo. Final report on the safety assessment of Capsicum annuum extract, Capsicum annuum fruit extract, Capsicum annuum resin, Capsicum annuum fruit powder, Capsicum frutescens fruit, Capsicum frutescens fruit extract, Capsicum frutescens resin, and capsaicin. Int J Toxicol 2007: 26 (Suppl 1): 3-106.
  • Bernstein JA, Davis BP, Picard JK, Cooper JP, Zheng S, Levin LS. A randomized, double-blind, parallel trial comparing capsaicin nasal spray with placebo in subjects with a significant component of nonallergic rhinitis. Ann Allergy Asthma Immunol. 2011; 107 (2): 171-8. doi: 10.1016/j.anai.2011.05.016.
  • Bortolotti M, Porta S. Effect of red pepper on symptoms of irritable bowel syndrome: preliminary study. Dig Dis Sci. 2011; 56 (11): 3288-95. doi: 10.1007/s10620-011-1740-9.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Capsicum annuum L. var. minimum (Miller) Heiser and small fruited varieties of Capsicum frutescens L., fructus. London: EMA. Doc. Ref.: EMA/HMPC/674139/2013. Adopted: 5 May 2015.
  • Gagnier JJ, van Tulder MW, Berman B, Bombardier C. Herbal medicine for low back pain: a Cochrane review. Spine (Phila Pa 1976. 2007; 32(1): 82-92.
  • Robbins W. Clinical applications of capsaicinoides. Clin J Pain 2000; 16 (2 suppl): S86-89.

Pimienta

  • Agbor G, Vinson J, Sortino J, Johnson R. Antioxidant and anti-atherogenic activities of three Piper species on atherogenic diet fed hamsters. Exp Toxicol Pathol (en prensa), doi:10.1016/j.etp.2010.10.003.
  • Butt MS, Pasha I, Sultan MT, Randhawa MA, Saeed F, Ahmed W. Black pepper and health claims: a comprehensive treatise. Crit Rev Food Sci Nutr. 2013; 53 (9) :875-86. doi: 10.1080/10408398.2011.571799.
  • Chavarria D, Silva T, Magalhães e Silva D, Remião F, Borges F. Lessons from black pepper: piperine and derivatives thereof. Expert Opin Ther Pat. 2016; 26 (2): 245-64. doi: 10.1517/13543776.2016.1118057.
  • Derosa G, Maffioli P, Sahebkar A. Piperine and its role in chronic diseases. Adv Exp Med Biol. 2016; 928: 173-184.
  • Hlavackova L, Urbanova A, Ulicna O, Janega P, Cerna A, Babal P. Piperine, active substance of black pepper, alleviates hypertension induced by NO synthase inhibition. Bratisl Lek Listy. 2010; 111 (8): 426-31.
  • Kapil A. Piperine. A potent inhibitor of Leishmania donovani promastigotes in vitro. Planta Medica 1993; 59 (5): 474.
  • Koul I, Kapil A. Evaluation of the liver protective potential of piperine, an active principle of black and long peppers. Planta medica 1993; 59 (5): 413.
  • Liu Y, Yadev V, Aggarwal B, Nair M. Inhibitory effects of black pepper (Piper nigrum) extracts and compounds on human tumor cell proliferation, cyclooxygenase enzymes, lipid peroxidation and nuclear transcription factor-kappa-B. Nat Prod Commun 2010; 5 (8): 1253-7.
  • Mahmoudpour Z, Shirafkan H, Mojahedi M, Gorji N, Mozaffarpur SA. Digesters in traditional Persian medicine. Caspian J Intern Med. 2018; 9 (1): 1-6. doi: 10.22088/cjim.9.1.1.
  • Meghwal M, Goswami TK. Piper nigrum and piperine: an update. Phytother Res. 2013; 27 (8): 1121-30. doi: 10.1002/ptr.4972.
  • Mehmood M, Gilani A. Pharmacological basis for the medicinal use of black pepper and piperine in gastrointestinal disorders. J Med Food 2010; 13 (5): 1086-96.
  • Mishra R, Singh S. Antispermatogenic and antifertility effects of fruits of Piper nigrum L. in mice. Indian J Exp Biol 2009; 47 (9): 706-14.
  • Rahman S, Parvez A, Islam R, Khan M. Antibacterial activity of natural spices on multiple drug resistant Escherichia coli isolated from drinking water, Bangladesh. Ann Clin Microbiol Antimicrob 2011; 10:10.
  • Sadati SN, Ardekani MR, Ebadi N, Yakhchali M, Dana AR, Masoomi F, et al. Review of scientific evidence of medicinal convoy plants in Traditional Persian Medicine. Pharmacogn Rev. 2016; 10 (19): 33-8. doi: 10.4103/0973-7847.176546.
  • Siddiqui B, Gulzar T, Begum S, Afshan F, Sultana R. A new natural product and insecticidal amides from seeds of Piper nigrum Linn. Nat Prod Res 2008; 22 (13): 1107-11.
  • Zheng J, Zhou Y, Li Y, Xu DP, Li S, Li HB. Spices for prevention and treatment of cancers. Nutrients. 2016; 8 (8). pii: E495. doi: 10.3390/nu8080495.
  • Zanzer YC, Plaza M, Dougkas A, Turner C, Östman E. Black pepper-based beverage induced appetite-suppressing effects without altering postprandial glycaemia, gut and thyroid hormones or gastrointestinal well-being: a randomized crossover study in healthy subjects. Food Funct. 2018;9(5):2774-2786. doi: 10.1039/c7fo01715d.

Poleo

  • Cheraghi Niroumand M, Farzaei MH, Karimpour Razkenari E, Amin G, Khanavi M, Akbarzadeh T, et al. An evidence-based review on medicinal plants used as insecticide and insect repellent in traditional Iranian medicine. Iran Red Crescent Med J. 2016;18(2):e22361. doi: 10.5812/ircmj.22361.
  • Nelson SD, McClanahan RH, Thomassen D, Gordon WP, Knebel N. Investigations of mechanisms of reactive metabolite formation from R-(+)-pulegone. Xenobiotica 1992; 22: 1157-1164.
  • Khonche A, Fallah Huseini H, Abdi H, Mohtashami R, Nabati F, Kianbakht S. Efficacy of Mentha pulegium extract in the treatment of functional dyspepsia: a randomized double-blind placebo-controlled clinical trial. J Ethnopharmacol. 2017; 206:267-73. doi: 10.1016/j.jep.2017.05.026.
  • Zhou S, Koh HL, Gao Y, Gong ZY, Lee EJ. Herbal bioactivation: the good, the bad and the ugly. Life Sci. 2004; 74: 935-968.

Regaliz

  • Bensch K, Tiralongo J, Schmidt K, Matthias A, Bone KM, Lehmann R, et al. Investigations into the antiadhesive activity of herbal extracts against Campylobacter jejuni. Phytother Res. 2011;25:1125-32.
  • Cao Y, Xu W, Huang Y, Zeng X. Licochalcone B, a chalcone derivative from Glycyrrhiza inflata, as a multifunctional agent for the treatment of Alzheimer's disease.
  • Nat Prod Res. 2018:1-4. doi: 10.1080/14786419.2018.1496429.
  • Chandrasekaran CV, Deepak HB, Thiyagarajan P, Kathiresan S, Sangli GK, Deepak M, et al. Dual inhibitory effect of Glycyrrhiza glabra (GutGard on COX and LOX products. Phytomedicine 2011; 18: 278-284.
  • Chigurupati H, Auddy B, Biyani M, Stohs SJ. Hepatoprotective effects of a proprietary glycyrrhizin product during alcohol consumption: a randomized, double-blind, placebo-controlled, crossover study. Phytother Res. 2016; 30 (12): 1943-1953. doi: 10.1002/ptr.5699.
  • Dastagir G, Rizvi MA. Review - Glycyrrhiza glabra L. (Liquorice). Pak J Pharm Sci. 2016; 29 (5): 1727-1733.
  • Dey S, Deepak M, Setty M, D'Souza P, Agarwal A, Sangli GK. Bioactive caffeic acids esters from Glycyrrhiza glabra. Nat Prod Res 2009; 23: 1657-1663.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Glycyrrhiza glabra L. and/or Glycyrrhiza inflata Bat. and/or Glycyrrhiza uralensis Fisch., radix. London: EMA. Doc. Ref.: EMA/HMPC/571119/2010. Adopted: 22/5/2012.
  • Hajiaghamohammadi AA, Zargar A, Oveisi S, Samimi R, Reisian S. To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori. Braz J Infect Dis. 2016; 20 (6): 534-538. doi: 10.1016/j.bjid.2016.07.015.
  • Hosseinzadeh H, Nassiri-Asl M. Pharmacological Effects of Glycyrrhiza spp. and its bioactive constituents: update and review. Phytother Res. 2015; 29 (12): 1868-86. doi: 10.1002/ptr.5487.
  • Jain E, Pandey RK, Khanna R. Liquorice root extracts as potent cariostatic agents in pediatric practice. J Indian Soc Pedod Prev Dent. 2013; 31 (3): 146-52. doi: 10.4103/0970-4388.117964.
  • Kao TC, Shyu MH, Yen GC. Glycyrrhizic acid and 18ß-glycyrrhetinic acid inhibit inflammation via PI3K/Akt/GSK3ß signaling and glucocorticoid receptor activation. J Agric Food Chem 2010; 58: 8623-8629.
  • Li JY, Cao HY, Liu P, Cheng GH, Sun MY. Glycyrrhizic acid in the treatment of liver diseases: literature review. Biomed Res Int. 2014; 2014: 872139. doi: 10.1155/2014/872139.
  • Martin MD, Sherman J, van der Ven P, Burgess J. A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. Gen Dent 2008; 56: 206-210.
  • Moghadamnia AA, Motallebnejad M, Khanian M. The efficacy of the bioadhesive patches containing licorice extract in the management of recurrent aphthous stomatitis. Phytother Res 2009; 23: 246-250.
  • Mukherjee M, Bhaskaran N, Srinath R, Shivaprasad HN, Allan JJ, Secar D, Agarwal AJ. Anti-ulcer and antioxidant activity of GutGard. Indian J Exp Biol 2010; 48: 269-274.
  • Najafi S, Koujan SE, Manifar S, Kharazifard MJ, Kidi S, Hajheidary S. Preventive effect of Glycyrrhiza Glabra extract on oral mucositis in patients under head and neck radiotherapy: a randomized clinical trial. J Dent (Tehran). 2017;14 (5): 267-274.
  • Nazari S, Rameshrad M, Hosseinzadeh H. Toxicological effects of Glycyrrhiza glabra (licorice): a review. Phytother Res. 2017;31(11):1635-1650. doi: 10.1002/ptr.5893.
  • Pastorino G, Cornara L, Soares S, Rodrigues F, Oliveira MBPP. Liquorice (Glycyrrhiza glabra): A phytochemical and pharmacological review. Phytother Res. 2018 Aug 17. doi: 10.1002/ptr.6178.
  • Peng F, Du Q, Peng C, Wang N, Tang H, Xie X, Shen J, Chen J. A Review: the pharmacology of isoliquiritigenin. Phytother Res. 2015; 29 (7): 969-77. doi: 10.1002/ptr.5348.
  • Puram S, Suh HC, Kim SU, Bethapudi B, Joseph JA, Agarwal A, Kudiganti V. Effect of GutGard in the Management of Helicobacter pylori: A randomized double blind placebo controlled study. Evid Based Complement Alternat Med. 2013;2013:263805. doi: 10.1155/2013/263805.
  • Ramalingam M, Kim H, Lee Y, Lee YI. Phytochemical and pharmacological role of liquiritigenin and isoliquiritigenin from radix glycyrrhizae in human health and disease models. Front Aging Neurosci. 2018;10:348. doi: 10.3389/fnagi.2018.00348.
  • Raveendra KR, Jayachandra, Srinivasa V, Sushma KR, Allan JJ, Goudar KS, et al. An extract of Glycyrrhiza glabra (GutGard) alleviates symptoms of functional dyspepsia: a randomized, double-blind, placebo-controlled study. Evid Based Complement Alternat Med. 2012; 2012:216970. doi: 10.1155/2012/216970.
  • Sadra A, Kweon HS, Huh SO, Cho J. Gastroprotective and gastric motility benefits of AD-lico/Healthy Gut™ Glycyrrhiza inflata extract. Animal Cells Syst (Seoul). 2017;21(4):255-262. doi: 10.1080/19768354.2017.1357660.
  • Sui X, Yin J, Ren X. Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by Pseudorabies herpesvirus. Antiviral Res 2010; 85: 346-353.
  • van Beers EJ, Stam J, van den Bergh WM. Licorice consumption as a cause of posterior reversible encephalopathy syndrome: a case report. Crit Care 2011; 15: R64.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.
  • Wittschier N, Faller G, Hensel A. Aqueous extracts and polysaccharides from Liquorice roots (Glycyrrhiza glabra L.) inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Ethnopharmacol 2009; 125: 218-223.
  • Wynn GJ, Davis GK, Maher B. Trick or treat? Pseudohyperaldosteronism due to episodic Licorice consumption. J Clin Hypertens 2011; 13: E3-4. doi: 10.1111/j.1751-7176.2010.00413.x
  • Yang R, Yuan BC, Ma YS, Zhou S, Liu Y. The anti-inflammatory activity of licorice, a widely used Chinese herb. Pharm Biol. 2017; 55 (1): 5-18

Romero

  • Andrade JM, Faustino C, Garcia C, Ladeiras D, Reis CP, Rijo P. Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity. Future Sci OA. 2018;4(4):FSO283. doi: 10.4155/fsoa-2017-0124.
  • Borges RS, Ortiz BLS, Pereira ACM, Keita H, Carvalho JCT. Rosmarinus officinalis essential oil: a review of its phytochemistry, anti-inflammatory activity, and mechanisms of action involved. J Ethnopharmacol. 2019;229:29-45. doi: 10.1016/j.jep.2018.09.038.
  • Catalán Ú, Barrubés L, Valls RM, Solà R, Rubió L. In vitro metabolomic approaches to investigating the potential biological effects of phenolic compounds: an update. Genomics Proteomics Bioinformatics. 2017; 15 (4): 236-245. doi: 10.1016/j.gpb.2016.12.007.
  • Chun KS, Kundu J, Chae IG, Kundu JK. Carnosol: a phenolic diterpene with cancer chemopreventive potential. J Cancer Prev. 2014 Jun;19(2):103-10. doi: 10.15430/JCP.2014.19.2.103.
  • de Oliveira MR. The dietary components carnosic acid and carnosol as neuroprotective agents: a mechanistic view. Mol Neurobiol. 2016; 53 (9): 6155-6168. doi: 10.1007/s12035-015-9519-1.
  • EMA-HMPC. Community herbal monograph on Rosmarinus officinalis L. folium. Doc. Ref. EMA/HMPC/13633/2009. Adopted: 17-7-2010.
  • EMA-HMPC. Community herbal monograph on Rosmarinus officinalis L. aetheroleum. London: EMA. Doc. Ref. EMA/HMPC/235453/2009. Adopted: 15-7-2010.
  • Ferreira LG, Celotto AC, Capellini VK, Albuquerque AA, Nadai TR, Carvalho MT, et al. Is rosmarinic acid underestimated as an experimental cardiovascular drug? Acta Cir Bras. 2013; 28 (Suppl 1): 83-7.
  • Ghasemian M, Owlia S, Owlia MB. Review of anti-inflammatory herbal medicines. Adv Pharmacol Sci. 2016; 2016: 9130979. doi: 10.1155/2016/9130979.
  • González-Vallinas M, Reglero G, Ramírez de Molina A. Rosemary (Rosmarinus officinalis L.) extract as a potential complementary agent in anticancer therapy. Nutr Cancer. 2015; 67 (8): 1221-9. doi: 10.1080/01635581.2015.1082110.
  • Habtemariam S. The Therapeutic Potential of Rosemary (Rosmarinus officinalis) Diterpenes for Alzheimer's disease. Evid Based Complement Alternat Med. 2016; 2016: 2680409. doi: 10.1155/2016/2680409.
  • Hassani FV, Shirani K, Hosseinzadeh H. Rosemary (Rosmarinus officinalis) as a potential therapeutic plant in metabolic syndrome: a review. Naunyn Schmiedebergs Arch Pharmacol. 2016; 389 (9): 931-49. doi: 10.1007/s00210-016-1256-0.
  • Miroddi M, Calapai G, Isola S, Minciullo PL, Gangemi S. Rosmarinus officinalis L. as cause of contact dermatitis. Allergol Immunopathol (Madr). 2014; 42 (6): 616-9. doi: 10.1016/j.aller.2013.04.006.
  • Naber KG. Efficacy and safety of the phytotherapeutic drug Canephron N in prevention and treatment of urogenital and gestational disease: review of clinical experience in Eastern Europe and Central Asia. Res Rep Urol. 2013 Feb 4;5:39-46. doi: 10.2147/RRU.S39288. Erratum in: Res Rep Urol. 2013; 5: 81.
  • Naimi M, Vlavcheski F, Shamshoum H, Tsiani E. Rosemary extract as a potential anti-hyperglycemic agent: current evidence and future perspectives. Nutrients. 2017;9(9). pii: E968. doi: 10.3390/nu9090968.
  • Nematolahi P, Mehrabani M, Karami-Mohajeri S, Dabaghzadeh F. Effects of Rosmarinus officinalis L. on memory performance, anxiety, depression, and sleep quality in university students: A randomized clinical trial. Complement Ther Clin Pract. 2018;30:24-28. doi: 10.1016/j.ctcp.2017.11.004.
  • Neves JA, Neves JA, Oliveira RCM. Pharmacological and biotechnological advances with Rosmarinus officinalis L. Expert Opin Ther Pat. 2018;28(5):399-413. doi: 10.1080/13543776.2018.1459570.
  • Ngo SN, Williams DB, Head RJ. Rosemary and cancer prevention: preclinical perspectives. Crit Rev Food Sci Nutr. 2011 Dec;51(10):946-54. doi: 10.1080/10408398.2010.490883.
  • Nieto G, Ros G, Castillo J. Antioxidant and antimicrobial properties of rosemary (Rosmarinus officinalis, l.): a review. Medicines (Basel). 2018;5(3). pii: E98. doi: 10.3390/medicines5030098.
  • Pengelly A, Snow J, Mills SY, Scholey A, Wesnes K, Butler LR. Short-term study on the effects of rosemary on cognitive function in an elderly population. J Med Food. 2012; 15 (1): 10-7. doi: 10.1089/jmf.2011.0005.
  • Petiwala SM, Johnson JJ. Diterpenes from rosemary (Rosmarinus officinalis): Defining their potential for anti-cancer activity. Cancer Lett. 2015; 367 (2): 93-102. doi: 10.1016/j.canlet.2015.07.005.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.

Salvia

  • Akhondzadeh S, Noroozian M, Mohammadi M, Ohadinia S, Jamshidi AH, Khani M. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial. J Clin Pharmacy Ther 2003; 28: 53-59.
  • Beheshti-Rouy M, Azarsina M, Rezaie-Soufi L, Alikhani MY, Roshanaie G, Komaki S. The antibacterial effect of sage extract (Salvia officinalis) mouthwash against Streptococcus mutans in dental plaque: a randomized clinical trial. Iran J Microbiol. 2015; 7 (3): 173-7.
  • Behradmanesh S, Derees F, Rafieian-Kopaei M. Effect of Salvia officinalis on diabetic patients. J Renal Inj Prev. 2013; 2 (2): 51-4. doi: 10.12861/jrip.2013.18.
  • Bommer S, Klein P, Suter A. First time proof of sage's tolerability and efficacy in menopausal women with hot flushes. Adv Ther 2011; 28 (6): 490-500. doi: 10.1007/s12325-011-0027-z.
  • Dos Santos-Neto LL, de Vilhena Toledo MA, Medeiros-Souza P, de Souza GA. The use of herbal medicine in Alzheimer's disease-a systematic review. Evid Based Complement Alternat Med 2006; 3 (4): 441-5
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Salvia officinalis L. folium London: EMA. Doc. Ref.: EMA/HMPC/277152/2015. Adopted: 20/09/2016.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Final Assessment report on Salvia officinalis L., folium and Salvia officinalis L., aetheroleum. London: EMA. Doc. Ref.: EMA/HMPC/150801/2015. Adopted: 15 February 2016.
  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). Public statement on the use of herbal medicinal products containing thujone. London: EMA. Doc. Ref.: EMA/HMPC/732886/2010 Rev.1. Adopted: 22 May 2012.
  • George J, Hegde S, Rajesh KS, Kumar A. The efficacy of a herbal-based toothpaste in the control of plaque and gingivitis: a clinico-biochemical study. Indian J Dent Res. 2009; 20 (4):480-2. doi: 10.4103/0970-9290.59460.
  • Ghasemian M, Owlia S, Owlia MB. Review of anti-inflammatory herbal medicines. Adv Pharmacol Sci. 2016; 2016: 9130979. doi: 10.1155/2016/9130979.
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Sanguinaria Flor

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Sen Hojas

  • Cañigueral S. El sen y los senósidos. Rubí: Lainco S.A., 1987.
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Stevia Hoja

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Té verde

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  • Kakuda T. Neuroprotective effects of theanine and its preventive effects on cognitive dysfunction. Pharmacol Res 2011; 64 (2): 162-8. doi: 10.1016/j.phrs.2011.03.010.
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  • Maslova E, Bhattacharya S, Lin SW, Michels KB. Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis. Am J Clin Nutr 2010; 92: 1120-32.
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  • Ogunleye AA, Xue F, Michels KB. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat 2010; 119: 477-84.
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Tila

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Tomillo

  • Cañigueral S, Vanaclocha B. Usos terapéuticos del Tomillo (Thymus vulgaris L. y Thymus zygis L.). Revista de Fitoterapia 2000; 1 (1): 5-13.
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  • Liu Q, Meng X, Li Y, Zhao CN, Tang GY, Li HB. Antibacterial and antifungal activities of spices. Int J Mol Sci. 2017; 18 (6). pii: E1283. doi: 10.3390/ijms18061283.
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  • Sharifi-Rad M, Varoni EM, Iriti M, Martorell M, Setzer WN, Del Mar Contreras M, et al. Carvacrol and human health: a comprehensive review. Phytother Res. 2018;32(9):1675-1687. doi: 10.1002/ptr.6103.
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  • Sõukand R, Quave CL, Pieroni A, Pardo-de-Santayana M, Tardío J, Kalle R, et al. Plants used for making recreational tea in Europe: a review based on specific research sites. J Ethnobiol Ethnomed. 2013; 9 (1): 58. doi: 10.1186/1746-4269-9-58.
  • Tohidpour A, Sattari M, Omidbaigi R, Yadegar A, Nazemi J. Antibacterial effect of essential oils from two medicinal plants against Methicillin-resistant Staphylococcus aureus (MRSA). Phytomedicine 2010; 17 (2): 142-5. doi: 10.1016/j.phymed.2009.05.007.
  • Vanaclocha B, Risco E, Cañigueral S. Interacciones entre preparados vegetales y fármacos de síntesis: revisión de las monografías de la EMA y ESCOP. Revista de Fitoterapia. 2014;14(1):5-36.

Valeriana

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  • Barton DL, Atherton PJ, Bauer BA, Moore DF Jr, Mattar BI, Lavasseur BI, et al. The use of Valeriana officinalis (Valerian) in improving sleep in patients who are undergoing treatment for cancer: a phase III randomized, placebo-controlled, double-blind study (NCCTG Trial, N01C5). J Support Oncol 2011; 9 (1): 24-31. doi: 10.1016/j.suponc.2010.12.008.
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  • Cuzzolin L, Francini-Pesenti F, Verlato G, Joppi M, Baldelli P, Benoni G.. Use of herbal products among 392 Italian pregnant women: focus on pregnancy outcome. Pharmacoepidemiol Drug Saf 2010; 19 (11): 1151-8. doi: 10.1002/pds.2040.
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  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Valeriana officinalis L., aetheroleum. London: EMA. EMA/HMPC/278053/2015. Adopted: 29/6/2016.
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Zajareña

  • European Medicines Agency (EMA) - Committee on Herbal Medicinal Products (HMPC). European Union herbal monograph on Sideritis scardica Griseb.; Sideritis clandestina (Bory & Chaub.) Hayek; Sideritis raeseri Boiss. & Heldr.; Sideritis syriaca L., herba Final. London: EMA. Doc. Ref.: EMA/HMPC/39453/2015. Adopted: 2 February 2016.
  • González Burgos E, Gómez-Serranillos Cuadrado MP, Palomino Ruiz-Poveda OM, Carretero Accame ME. Aspectos botánicos y farmacológicos del género Sideritis. Revista de Fitoterapia 2009; 9 (2): 133-145.